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Adefovir dipivoxil (Hepsera)
This phosphonate nucleoside analog, administered as the oral prodrug, inhibits replication of HBV, including variants resistant to lamivudine. Adefovir treatment of HBeAg-positive or -negative chronic hepatitis B is associated with marked reductions in HBV DNA levels, aminotransferase normalization in 48% to 72% of patients, and histologic improvements in 53% to 64% at 48 weeks. More prolonged therapy results in higher rates of response; anti-HBeAg seroconversion occurs in 23% by 72 weeks. The antiviral effects of adefovir are similar in lamivudine-susceptible and -resistant HBV infections (MG Peters et al, Gastroenterology 2004; 126:91). Some experts recommend adefovir over lamivudine for long-term treatment of HBeAg-negative or cirrhotic patients because of the high risk of emergence of lamivudine resistance.
Where does hematopoiesis occur? Hematopoiesis happens in the bone marrow (mainly within flat bones), where erythrocytes, leukocytes and platelets are made, and in the lymphoid
Q. Conditions required for Mimicking Pericardial Effusion? In 2DE few conditions can mimic PE. a) Pericardial fat-Mostly localized anteriorly. Absence of fat in the posterio
State about osteogenesis Embryologically, osteogenesis may be classified as either intramembranous or endochondral. When the ossification occurs directly, it is defined as intr
Q. What are anteromedial aspects of temporal lobes? Olfactory Cortex - found in anteromedial aspects of temporal lobes receive sensory information directly from the olfactory n
Drug Intolerance For patients who cannot tolerate rifampin, alternative regimens include 9-12 months of isoniazid, ethambutol and pyrazinamide, with or without a fluoroquinolo
It is elimination of an antigen or antibody from a sample by the process of adsorption, to which the complimentary antigen or antibody is bound.
Define the Principle behind Cyanmethemoglobin Method? The principle behind the cyanmethemoglobin method is as follow: Principle The haemoglobin is treated with a reagent con
What are the grasslands of North America and of South America respectively called? The steppe grasslands of North America are known as prairies. The grasslands of South America
BLOOD COAGULATION - DEFINITIO N - The property of blood to change from fluid to gel state within a few minutes of its coming in contact with air is called blood coag
Ask question #M1. Discuss why Obelia is considered to be of special interest in Zoology as an animal showing an intermediate grade of organization. inimum 100 words accepted#
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