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Resistance
Acyclovir-resistant HSV occurs mainly in immunocom- promised patients treated with the drug; isolates are usually also resistant to valacyclovir and famciclovir. Resistant HSV infection in HIV-positive patients has been associated with progressive mucosal disease and, rarely, visceral involvement. Acyclovir-resistant VZV strains in HIV-positive patients have been associated with chronic cutaneous lesions and, rarely, invasive disease.
Q. In the phase when the cell is not dividing interphase is there activity within the cell nucleus? In the interphase there is intense metabolic activity in the cell nucleus th
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