Explain about the zinc toxicity, Biology

Assignment Help:

Explain about the Zinc Toxicity?

Only a few occurrences of acute zinc poisoning have been reported. The toxicity signs are nausea, vomiting, diarrhoea, fever and lethargy and have been observed after ingestion of 4-8 g (60-120 mmol) of zinc. Gross acute zinc toxicity has been reported after consuming water stored in galvanized containers. Symptoms include nausea, vomiting and fever. These symptoms are observed after ingestion of 2g or more of zinc. Long-term zinc intakes higher than requirements could, however, interact with the metabolism of other trace elements. Copper seems to be especially sensitive to high zinc doses.

A zinc intake of 50 mg/day (760 μmol) affects copper status. Because copper also has a central role in immune defence, these observations should be studied further before large-scale zinc supplementation programmes are undertaken. Any positive effects of zinc supplementation on growth or infectious diseases could be offset by associated negative effects on copper-related functions. Intakes between 25 -50 mg zinc per day have been reported to interfere with metabolism of both iron and copper. FAONHO 2004 therefore recommended the upper level of zinc intake for an adult man at 45 mg/day (690 μmol/day) and extrapolated to other groups in relation to basal metabolic rate. For children, this extrapolation means an upper limit of intake of 23-28 mg/day (350-430 μmol/day), which is close to what has been used in some of the zinc supplementation studies. Except for excessive intakes of some types of seafood, such intakes are unlikely to be attained with most diets. Adventitious zinc in water from contaminated wells and from galvanized cooking utensils could also lead to high zinc intakes.

 


Related Discussions:- Explain about the zinc toxicity

Define role of fitness in field of human endeavour, Define Role of Fitness ...

Define Role of Fitness in Field of Human Endeavour? Fitness plays a vital role in any field of human endeavour and influences the efficiency of a person. For this reason, fitne

Define reagents-nelson somogyi method for glucose estimation, Define Reagen...

Define Reagents - Nelson Somogyi Method for Glucose Estimation? 1. Alkaline copper reagent Alkaline A- Buy commercial from SDS chemicals etc Alkaline B- Weigh 6.25 g anhy

How can the blood coagulation process be described, How can the blood coagu...

How can the blood coagulation (clotting) process be described? Blood clotting encompasses a sequence of chemical reactions whose respective products are enzymes that catalyze t

What does vacuoles do, What does vacuoles do? It is an organelle, locat...

What does vacuoles do? It is an organelle, located in the cell's cytoplasm, which is the site of protein synthesis. It is really a protein having of 2 parts. These 2 "parts"

Explain positive staining technique, Explain Positive Staining Technique? ...

Explain Positive Staining Technique? Here, a stain has a positively charged chromophore that gets attached to the negatively charged outer surface of the microbial cell and thu

Hazards of oxygen therapy - respiratory failure, Hazards of O 2 Therapy ...

Hazards of O 2 Therapy Exposure to greater than 60 per cent O 2 , for a period of more than 36 hours, or exposure to 100 per cent 0, for a period of more than 6 hours, res

Why are vaccines used in the prevention, Q. Why are vaccines used in the pr...

Q. Why are vaccines used in the prevention but not in the treatment of infections? Why can antivenom serums be used in prevention and treatment? Vaccines are not used in the tr

Adaptive mechanisms, The adaptive mechanisms may be short term ones which c...

The adaptive mechanisms may be short term ones which come into play within minutes or hours of the onset of myocardial dysfunction. These are: Frank-Starling Mechanism In

Define the enzyme function of vitamin c, Define the Enzyme Function of Vita...

Define the Enzyme Function of Vitamin C? Vitamin C acts as an electron donor for 11 enzymes. Three of those enzymes are found in fungi but not in humans. Of the eight remainin

Respiration, difference between anaerobic respiration and fermentation

difference between anaerobic respiration and fermentation

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd