Explain about the zinc toxicity, Biology

Assignment Help:

Explain about the Zinc Toxicity?

Only a few occurrences of acute zinc poisoning have been reported. The toxicity signs are nausea, vomiting, diarrhoea, fever and lethargy and have been observed after ingestion of 4-8 g (60-120 mmol) of zinc. Gross acute zinc toxicity has been reported after consuming water stored in galvanized containers. Symptoms include nausea, vomiting and fever. These symptoms are observed after ingestion of 2g or more of zinc. Long-term zinc intakes higher than requirements could, however, interact with the metabolism of other trace elements. Copper seems to be especially sensitive to high zinc doses.

A zinc intake of 50 mg/day (760 μmol) affects copper status. Because copper also has a central role in immune defence, these observations should be studied further before large-scale zinc supplementation programmes are undertaken. Any positive effects of zinc supplementation on growth or infectious diseases could be offset by associated negative effects on copper-related functions. Intakes between 25 -50 mg zinc per day have been reported to interfere with metabolism of both iron and copper. FAONHO 2004 therefore recommended the upper level of zinc intake for an adult man at 45 mg/day (690 μmol/day) and extrapolated to other groups in relation to basal metabolic rate. For children, this extrapolation means an upper limit of intake of 23-28 mg/day (350-430 μmol/day), which is close to what has been used in some of the zinc supplementation studies. Except for excessive intakes of some types of seafood, such intakes are unlikely to be attained with most diets. Adventitious zinc in water from contaminated wells and from galvanized cooking utensils could also lead to high zinc intakes.

 


Related Discussions:- Explain about the zinc toxicity

Cooking of vitamin c-containing foods, Q. Why isn't the cooking of vitamin ...

Q. Why isn't the cooking of vitamin C-containing foods appropriate for vitamin C supply? To obtain vitamin C, for instance, from an orange dessert, the vitamin- containing food

Coarctation of aorta, Careful palpation of the upper and lower limb pulses ...

Careful palpation of the upper and lower limb pulses would make one suspect coarctation as the cause of hypertension. The lower limb pulses are weak and delayed. Confirmation ca

How is the concentration of drugs in human plasma defined, Some drugs bind ...

Some drugs bind extensively to plasma proteins (Warfarin binds 99%) while others have virtually no binding. Extraction depends on the type of drug - there are dissimilar standar

What is the meaning of oedema, What is the meaning of Oedema? In some p...

What is the meaning of Oedema? In some pathological conditions the body is in a positive water balance; that is the intake of fluids is greater than the excretion, and the pati

Unconventional feed resources and anti-nutritional factors, Unconventional ...

Unconventional Feed Resources and Anti-Nutritional Factors With increasing ruminant population, there is a need to identify and introduce new and lesser-known food and feed cro

Explain about atrial septal defect, Explain about Atrial Septal Defect (ASD...

Explain about Atrial Septal Defect (ASD) ? ASD occurs as an isolated anomaly in 5- 10 per cent of all CHDs. These communications occur in four sites i.e. in the central portion

Ciliated protozoan, Ciliated Protozoan Ciliates form the largest and t...

Ciliated Protozoan Ciliates form the largest and the most homogenous group of protozoans. They are placed under one phylum Ciliophora and evidence indicates that its members s

rumen protection of nutrient (bypass nutrients) technology, Rumen protecti...

Rumen protection of nutrient (bypass nutrients) technology The amino acid and energy requirements of medium and high yielding cows and buffaloes are not fully met from the micr

Which kind of polarity do fat-soluble substance has, Q. Which kind of polar...

Q. Which kind of polarity do fat-soluble and water-soluble substances respectively have? Ans. Water-soluble substances are behave as polar molecules, i.e., they have e

Define the food sources of thiamin, Define the Food Sources of Thiamin? ...

Define the Food Sources of Thiamin? Thiamin is present in many food products and depending on the amount of vitamin present, we have categorized the foods as rich, good or fair

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd