Explain about the zinc toxicity, Biology

Assignment Help:

Explain about the Zinc Toxicity?

Only a few occurrences of acute zinc poisoning have been reported. The toxicity signs are nausea, vomiting, diarrhoea, fever and lethargy and have been observed after ingestion of 4-8 g (60-120 mmol) of zinc. Gross acute zinc toxicity has been reported after consuming water stored in galvanized containers. Symptoms include nausea, vomiting and fever. These symptoms are observed after ingestion of 2g or more of zinc. Long-term zinc intakes higher than requirements could, however, interact with the metabolism of other trace elements. Copper seems to be especially sensitive to high zinc doses.

A zinc intake of 50 mg/day (760 μmol) affects copper status. Because copper also has a central role in immune defence, these observations should be studied further before large-scale zinc supplementation programmes are undertaken. Any positive effects of zinc supplementation on growth or infectious diseases could be offset by associated negative effects on copper-related functions. Intakes between 25 -50 mg zinc per day have been reported to interfere with metabolism of both iron and copper. FAONHO 2004 therefore recommended the upper level of zinc intake for an adult man at 45 mg/day (690 μmol/day) and extrapolated to other groups in relation to basal metabolic rate. For children, this extrapolation means an upper limit of intake of 23-28 mg/day (350-430 μmol/day), which is close to what has been used in some of the zinc supplementation studies. Except for excessive intakes of some types of seafood, such intakes are unlikely to be attained with most diets. Adventitious zinc in water from contaminated wells and from galvanized cooking utensils could also lead to high zinc intakes.

 


Related Discussions:- Explain about the zinc toxicity

Determine the number of cell clusters, A cellular system has a total of 500...

A cellular system has a total of 500 duplex voice channels. The service area is divided into 150 cells. Suggest a three different cluster size (N) values. In each case, determine

Explain about the component of metalloenzymes, Explain about the Component ...

Explain about the Component of Metalloenzymes? Zinc is unique among the trace elements in that it is a part of enzymes for all six Enzyme Commission classes. As a component of

Explain capillaries of the vascular system, Q. What are the capillaries of ...

Q. What are the capillaries of the vascular system? Capillaries are small blood vessels that perform exchange of substances between the tissues and blood the body Capillaries a

Explain properties of amylopectin and amylose, Properties of Amylopectin an...

Properties of Amylopectin and Amylose In plants, starch is packaged in granules, which vary in their  shape and size, when isolated from different sources. The size of these gr

How lysosomal enzymes involved in the scavenging of aged, How Lysosomal enz...

How Lysosomal enzymes involved in the scavenging of aged Lysosomal enzymes are also involved in the scavenging of aged and damaged cells. In several diseased states and also by

Define excretion of toxin and act as precursor- carbohydrate, Define Excret...

Define Excretion of toxins and Act as precursors? Excretion of toxins: Glucuronic acid, a metabolite of glucose, combines with chemical and bacterial toxins and some normal met

How are the epithelial tissues classified, Q. How are the epithelial tissue...

Q. How are the epithelial tissues classified? The epithelial tissues are classified according to the shape of the cells that form it epithelial cells may be columnar, cuboidal,

What are deciduous trees, What are deciduous trees? The Deciduous trees...

What are deciduous trees? The Deciduous trees are plants that lose their leaves in a period of the year and in the case of the deciduous trees of the temperate forest the fall

Major types of inheritances exceptions to mendel''s rules/, According to th...

According to the Mendel's law the phenotypical characteristics would be determined by pair of factors (alleles) that separate independently in gametes. What are the major types of

Slow walking or crawling, Slow walking or Crawling This type of locom...

Slow walking or Crawling This type of locomotion is seen while the animal moves on the substratum. It involves a metachronal rhythm of action in the parapodia. Each fifth or

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd