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Explain about the Vitamin D?
Vitamin D is a generic term and indicates a molecule of the general structure with rings (A, B, C, D), as you may have noticed in Figure B. The ring structure is derived from the cyclopentanoper hyclrophenenthrene ring structure for steroids. Ergocalsiferol (D2), cholecaliferol (D3) are the forms of vitamin D.
Vitamin D, can either be made in the skin from a cholesterol-like precursor (7-dehydrocholesterol) by exposure to sunlight or can be provided pre-formed in the diet. The version made in the skin is referred to as vitamin D3 whereas the dietary form can be either vitamin D3 or a closely-related molecule of plant origin known as vitamin D2. Figure m shows the formation of Vitamin D3 from its precursor 7-dehydrocholesterol. The synthesis of vitamin D3 from its provitamin, 7-dehydrocholesterol, occurs by UV irradiation and proceeds from the provitamin to the previtamin and finally to the vitamin. The first main step of the reaction is the photochemical conversion of 7-dehydrocolesterol to previtamin D3. This reaction yields upto 85% of previtamin D3. The next and final step is accomplished by the thermal conversion of previtamin D, to vitamin D3.
Researchers (Helle et al., 2004) analyzed rates of twin births in the Sami population of Northern Scandinavia during the eighteenth and nineteenth centuries. They found that (1) a
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