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Explain about the Sucralose - artificial sweeteners?
Sucralose (1, 6-dichloro-1, 6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D- galactopyranoside) is the only non-nutritive sweetener based on sucrose.
Its structure is displayed in the diagram for your better understanding. It is selectively chlorinated and the glycosidic link between the two rings is resistant to hydrolysis by acid or enzymes thus, it is not metabolised. It is 400-800 times sweeter as compared to sucrose. It is extremely soluble in water and is stable to heat.
Assuming that the equilibrium potential for sodium ion across a skeletal muscle is +66 mv at a temperature of 37 degree celcius when the external concentration is 145 mM and the in
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