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Explain about the Neuro Trauma?
Neuro or head trauma includes brain injury, skull fractures, extraparenchymal or internal brain haemorrhage, Brain injury can be divided into three types. These include:
- Concussion means brief loss of consciousness (< 6 hours),
- Contrusion is similar to a bruise on the skin, 2nd
- Comminution means splintering of bone in many fractures.
Like other cases of major injury and trauma, as you now know Cram Unit 5, brain injury or trauma also results in a systemic hypermetabolic, hypercatabolic response. This affects the entire body as body reserves get mobilized. If this resultant hypermetabolic state remains unchecked, a sequence of' organ failure can results. Neuro trauma results in production of cytokines, these effect the metabolism. Some of the effects of this are fever, neutrophilia (type of while blood cells which provide important defence mechanism are increased in number), muscle breakdown, altered amino acid metabolism, increased organ demise.
Match each of the methods or vectors below to an appropriate form of gene therapy, assigning two methods or vectors to each form. Use each method or vector only once. Methods/vec
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