Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
M protein of rheumatogenic GAS has distinct structural characteristics that are akin to human heart tissue, particularly sarcolemmal membrane proteins and cardiac myosin. The major factors that lead to risk of ARF are the severity of the immune response to GAS pharyngitis and persistence of GAS organisms during convalescence. A very small proportion (0.3-3 per cent) of patients suffering from GAS throat infection ultimately develop ARF and this along with a familial predisposition of ARF points to a genetic susceptibility. However, in our Indian patients a genetic linkage to HLA DR3 in patients, with ARF has been demonstrated. For confirmation of the initial diagnosis of acute rheumatic fever, evidence of prior GAS infection is required. Several rapid GAS antigen tests are available. Majority of these tests has a high degree of specificity but low level of sensitivity in clinical practice.
However, it must be stressed that a negative test does not rule out the GAS infection in the throat. At the same time in presence of a positive antigen test and positive throat culture, it is difficult to distinguish between a recent infection which can be associated with ARF and chronic carrier of GAS infection with ARF. Elevated or rising ASO titres (> 250Todd units in adults and >333 Todd units in children) are more reliable evidence of recent GAS infection than a positive culture or positive rapid antigen test and such titres are also significant for diagnosis.
How does chemical adsorption of a gas on a solid vary with temperature? a) Mention the main reason for the anomalous behaviour of lithium in Group of the periodic table.
What is the classification scheme for echinoderms?
Q. What happens to the TSH (thyroid-stimulating hormone) blood level in hypothyroidism? Why is there enlargement of the thyroid in the endemic goiter disease? When there is low
For homework, I had to prove that a certain catalyst was a protein, then tell how I would purify the protein, then tell how I would clone a human chromosomal region that contains t
Define Transport and uptake of Zinc by Cells? After absorption, zinc is bound to albumin and transported to the liver. In liver, it is concentrated and then transported to diff
Define Counter Stain - Staining Technique? Finally, the smear is counter stained with a simple basic dye different in colour from crystal violet. Safranin is the most commonly
Why Pulses are important for human - nutritional factor? Pulses are rich sources of proteins (20-25 g/100 g), the limiting amino acid being methioniize. However, protein quality
In genetic recombination by crossing over what is the difference between parental gametes and recombinant gametes? The Parental gametes are those gametes that maintain the orig
organisms and their excretory organelles
What is Ceramics A kind of material that is "bone like" based on the specific ratios of calcium and phosphorous in particular crystalline structures. Ceramics are inorganic, no
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd