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M protein of rheumatogenic GAS has distinct structural characteristics that are akin to human heart tissue, particularly sarcolemmal membrane proteins and cardiac myosin. The major factors that lead to risk of ARF are the severity of the immune response to GAS pharyngitis and persistence of GAS organisms during convalescence. A very small proportion (0.3-3 per cent) of patients suffering from GAS throat infection ultimately develop ARF and this along with a familial predisposition of ARF points to a genetic susceptibility. However, in our Indian patients a genetic linkage to HLA DR3 in patients, with ARF has been demonstrated. For confirmation of the initial diagnosis of acute rheumatic fever, evidence of prior GAS infection is required. Several rapid GAS antigen tests are available. Majority of these tests has a high degree of specificity but low level of sensitivity in clinical practice.
However, it must be stressed that a negative test does not rule out the GAS infection in the throat. At the same time in presence of a positive antigen test and positive throat culture, it is difficult to distinguish between a recent infection which can be associated with ARF and chronic carrier of GAS infection with ARF. Elevated or rising ASO titres (> 250Todd units in adults and >333 Todd units in children) are more reliable evidence of recent GAS infection than a positive culture or positive rapid antigen test and such titres are also significant for diagnosis.
Types of Axons Axons are of two types Myelinated and Non-myelinated In the case of myelinated axons the neurilemma is ensheathed by another cover
Treatment options for ailing and failing implants are varied. The clinician should start conservatively and progress to more aggressive therapy. The overall goal of therapy is
biostatistical application in biotechnology
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State the Classification of nervous system Neurological disorders can be categorised according to the primary location affected, the primary type of dysfunction involved, or th
Carbon paper leaf prints Cover the vein side of a leaf with a very thin layer of lard or vaseline. Place the greased leaf vein side up on various layers of newspaper and cover
HOW ARE THE ORIGIN AND EVOLUTION OF ALGAE..
Q. What are the main opportunistic diseases that can affect AIDS patients? Among the opportunistic diseases that affect HIV contaminated people during the AIDS stage some are:
what is radula?
1) The oxidative phase generates NADPH The oxidative branch of the pathway generates NADPH and pentose-5-phosphate, through the following reactions: a) Glucose-6-pho
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