Elaborates the pathophysiology of ventricular septal defect, Biology

Assignment Help:

Elaborates the Pathophysiology of ventricular septal defect?

The shunt in the VSD is left to right. The magnitude of the shunt is determined by the size of the VSD and the, level of pulmonary vascular resistance. The lower the PVR, the greater the magnitude of L>R shunt. This type of shunt is called dependent shunt. In VSD the LV starts contracting before RV, and high-pressure gradient is maintained between two ventricles throughout systole. Hence the murmur is pansystolic. Towards the end of the systole, the declining LV pressure becomes lower than the aortic valve with occurrence of A2. However the LVSP > RVSP, and left to right shunt continues.

The pansystolic murmur therefore ends beyond A2 completely masking it. The increased volume of blood finally reaches the LA I LV resulting in volume overload if LA/ LV. Passing through a normal mitral valve, the large volume of blood results in MDM at the apex. This is a very useful clue indicating a large flow and operability of the lesion. Since the left ventricle has two outlets it empties relatively early, this results in early A2.Since ejection into RV and PA is increased, P2 is delayed. Therefore the S2 is widely split but varies with respiration. In a large VSD with increasing PVR, 52 splitting become less and less obvious. It is single once PVR is significantly elevated.

 


Related Discussions:- Elaborates the pathophysiology of ventricular septal defect

Classification, what is the mode of nutrition in fungi?

what is the mode of nutrition in fungi?

What is the rule for the pairing of nitrogen-containing base, Q. What is th...

Q. What is the rule for the pairing of nitrogen-containing bases in the DNA molecule? And in the RNA? Is this the last question appropriate? The rule for the pairing of nitroge

Which glands secrete their product into circulatory system, Name of the duc...

Name of the ductless glands that secrete their product into the circulatory system are: a) Exocrine (pron: ek-seh-kren) b) Apocrine (pron: ap-eh-kren) c) Holocrine (pron:

Non living vs. living matter, Non living vs. Living matter As is cl...

Non living vs. Living matter As is clear from above   account the energy of matter resides in its chemical organization. The total potential chemical energy, entrapped as b

Describe the concept of soil testing, Describe the concept of soil testing ...

Describe the concept of soil testing Different grades of complex and mixed fertilizers are being marketed to suit the soil and crops of a region. The recommendations are made o

Integral membrane protein movement and distribution, Various proteins are f...

Various proteins are free to take a move laterally in the plane of the bilayer. One experiment used to represent this included fusing cultured mouse cells with human cells under ap

Features of estuaries, Features of Estuaries The physicochemical prop...

Features of Estuaries The physicochemical properties of the estuaries have large variation in several parameters and this often creates stressful environment for organisms. T

Animal around us, #question.what are the reason that arthropodans are abund...

#question.what are the reason that arthropodans are abundant in nature.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd