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This is extension of the EM algorithm which typically converges more slowly than EM in terms of the iterations but can be much faster in the whole computer time. The general idea of the algorithm is to replace M-step of each EM iteration with the sequence of S >1conditional or constrained maximization or the CM-steps, each of which maximizes the expected complete-data log-likelihood found in the previous E-step subject to constraints on parameter of interest, θ, where the collection of all the constraints is such that the maximization is over the full parameter space of θ. Because the CM maximizations are over the smaller dimensional spaces, many times they are simpler, faster and more reliable than corresponding full maximization known in the M-step of the EM algorithm.
The distribution free or technique which is the analogue of the analysis of variance for the design with two factors. It can be applied to data sets which do not meet the assumptio
calculate absorbance value from concentration
A term commonly encountered in the application of the agglomerative hierarchical clustering techniques, where it refers to the 'tree-like' diagram illustrating the series of steps
Multiple imputation : The Monte Carlo technique in which missing values in the data set are replaced by m> 1 simulated versions, where m is usually small (say 3-10). Each of simula
Randomized consent design is the design at first introduced to overcome some of the perceived ethical problems facing clinicians entering patients in the clinical trials including
Helmert contrast is the contrast often used in analysis of the variance, in which each level of a factor is tested against average of the remaining levels. So, for instance, if th
Causality: The relating of the reasons to the effects they produce. Several investigations in medicine seek to establish the causal relations between the events, for instance, whi
The approach to data analysis which emphasizes the use of informal graphical procedures not based on former assumptions about structure of the data or on the formal models for the
Treatment allocation ratio is the ratio of the number of subjects allocated to the two treatments in a clinical trial. The equal allocation is most usual in practice, but it might
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