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This is extension of the EM algorithm which typically converges more slowly than EM in terms of the iterations but can be much faster in the whole computer time. The general idea of the algorithm is to replace M-step of each EM iteration with the sequence of S >1conditional or constrained maximization or the CM-steps, each of which maximizes the expected complete-data log-likelihood found in the previous E-step subject to constraints on parameter of interest, θ, where the collection of all the constraints is such that the maximization is over the full parameter space of θ. Because the CM maximizations are over the smaller dimensional spaces, many times they are simpler, faster and more reliable than corresponding full maximization known in the M-step of the EM algorithm.
how to constuct design matrix
Probit analysis is the technique most commonly employed in the bioassay, specifically toxicological experiments where the group of animals is subjected to known levels of a toxin
meaning,uses,shortcomings and drawbacks of vital statistics
Records on the computer manufacturing process at Pratt-Zungia Limited show that the percentage of defective computers sent to customers has been 5% over the last few years. Shipme
Informed consent: The consent needed from each potential participant former to random assignment in the clinical trial as speci?ed in the year 1996 version of Helsinki declaration
The total amount of protein produced by a dairy cow can be estimated from periodic testing of her milk. The following are the total annual protein production values (lb) for 28 tw
It is the technique used in the clinical trials when it is possible to make an acceptable place before an active treatment but not to make the two active treatments identical. In t
Blinding : A procedure used in clinical trials to get rid of the possible bias which might be introduced if the patient and/or the doctor knew which treatment the patient is receiv
Consider a decision faced by a cattle breeder. The breeder must decide how many cattle he should sell in the market each year and how many he should retain for breeding purposes. S
Consolidated Standards for Reporting Trials (CONSORT) statement : The protocol for reporting the results of the clinical trials. The core contribution of the statement comprises of
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