LIVER (HEPAR) -

1. Largest gland of body. Weighing 1.6 kg. Form 1/40 of the body weight. Bio-chemical laboratory.
2. Bussiest part in whole river of life. Dark reddish brown in colour.
3. Situated on right side attaches to posterior concavity of diaphragm by a fold of peritonium i.e. Falciparum ligament.
4. Bile juice is synthesized and secreted by cholerosis.
5. It is made up of 4 lobes- right lobe, left lobe, quadrate & caudata lobe. (In rabbit 5 lobes).
6. On right central lobe gall bladder is situated. Gall bladder stores bile juice.
7. Its basal part is fundus. Its duct is cystic duct.
8. Gall bladder is absent in rodent, cetacean & parissodactyla.
9. Stone in gall bladder is cholycystosis due to more concentration of cholesterol which causes crystalization.
10. Each lobe is made up of numerous lobules. Structure of each lobule is similar.
11. It is surrounded by Glisson's capsule.
12. Lobule is made up hepatic cells which form radially arranged hepatic cords.
13. Between two hepatic cords blood sinuoids present.
14. On periphery Kupffer's cells present, phagocytic in nature.
15. On each corner of lobule portal traid present in which hepatic artery interlobular vein (part of hepatic portal sy.) & bile duct present. In hepatic cell conaliculli present.
16. All canaliculi open into Hering's canal which form bile duct.
17. Hepatic artery and inter labular vein supply blood to liver.
18. Blood is collected from lobule by large central singel intralobular vein.