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Describe the term Epinephrine?
Epinephrine is administered IV in increments of 1 mg diluted in 10 mls of normal saline (1:10,000). It can be given through the endotracheal tube as well in a 2 - 3mg dose. This should be diluted in 10 mls of normal saline. Following tracheal instillation, five ventilations should be given to disperse the drug peripherally to optimize absorption. Epinephrine optimizes the efficacy of CPR, mainly through its alpha adrenergic effect, by raising the coronary and cerebral perfusion pressures.
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How do leucine zipper binding motifs regulate gene expression?
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