Describe the regulation of pyruvate dehydrogenase, Biology

Assignment Help:

Describe the regulation of pyruvate dehydrogenase through covalent modification.

PDH exists in 2 forms :  Inactive, phosphorylated and Active, dephosphorylated. The active form of PDH is phosphorylated by a protein kinase with the help of ATP and Mg++ to  the inactive  form of PDH. Acetyl CoA  and NADH are activators for this action and CoA, NAD+,  and pyruvate are inhibitors. The inactive  form of PDH is dephosphorylated by phosphoprotein phosphatase to the active form in the presence of increased Ca++  ion concentration.

 


Related Discussions:- Describe the regulation of pyruvate dehydrogenase

What are anteromedial aspects of temporal lobes, Q. What are anteromedial a...

Q. What are anteromedial aspects of temporal lobes? Olfactory Cortex - found in anteromedial aspects of temporal lobes receive sensory information directly from the olfactory n

Parts, How many parts of human body?

How many parts of human body?

What is the mechanism described by darwin, What is the mechanism described ...

What is the mechanism described by Darwin that eliminates species less adapted to environmental conditions? The mentioned mechanism is the natural selection.

Pulmonary valvotomy cardio bypass and use cardioplegia, Pulmonary Valvo...

Pulmonary Valvotomy on Cardio Pulmonary Bypass and use of Cardioplegia :  Single aortic cannulation and separate SVC and IVC cannulation arc done. The cavae are snared to

Blotting, Blotting  is the technique for detecting one RNA within the mixtu...

Blotting  is the technique for detecting one RNA within the mixture of RNAs (a Northern blot) or one type of the DNA within of a mixture of DNAs (a Southern blot). A blot can prove

Acute mitral regurgitation-mitral regurgitation, Acute Mitral Regurgitation...

Acute Mitral Regurgitation :  This may be caused by chordal rupture, infective endocarditis or acute myocardial infarction. In acute myocardial infarction, one of the papilla

Tissue culture, Note on production of haploid by tissue culture.

Note on production of haploid by tissue culture.

Determine the symptoms of cholera, Determine the Symptoms of Cholera  A...

Determine the Symptoms of Cholera  An infective dose of around one million organisms should be ingested to cause illness. The bacteria adhere to the small intestine wall, where

Concepts of migration - emigration and immigration, Q. How different are th...

Q. How different are the concepts of migration, emigration and immigration? The Migration is the moving of individuals of a species from one place to another. The Emigration is

Define citric acid cycle, The citric acid cycle also called as the TCA cycl...

The citric acid cycle also called as the TCA cycle (tricarboxylic acid cycle) and the Krebs cycle or the Szent-Györgyi-Krebs cycle is a series of chemical reactions used by all aer

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd