Describe the regulation of pyruvate dehydrogenase, Biology

Assignment Help:

Describe the regulation of pyruvate dehydrogenase through covalent modification.

PDH exists in 2 forms :  Inactive, phosphorylated and Active, dephosphorylated. The active form of PDH is phosphorylated by a protein kinase with the help of ATP and Mg++ to  the inactive  form of PDH. Acetyl CoA  and NADH are activators for this action and CoA, NAD+,  and pyruvate are inhibitors. The inactive  form of PDH is dephosphorylated by phosphoprotein phosphatase to the active form in the presence of increased Ca++  ion concentration.

 


Related Discussions:- Describe the regulation of pyruvate dehydrogenase

Rule of distal transformation of blastema, Rule of Distal Transformation of...

Rule of Distal Transformation of Blastema An intriguing phenomenon characteristic of limb regeneration is, that just only the part of the limb removed distal to the level of a

Medical management of chronic renal failure, Medical Management   In ch...

Medical Management   In chronic  renal failure  there  is irreversible renal failure. The goals of medical management are:   To promote maximal  renal  function  To ma

What is chylomicrons , Chylomicrons, the widest of the lipoproteins, are...

Chylomicrons, the widest of the lipoproteins, are synthesized in the intestine. They including ingested triacylglycerols to other tissues, mainly skeletal muscle and adipose tissue

Do octopus and squids have exoskeleton, Do octopus and squids have exoskele...

Do octopus and squids have exoskeleton? Octopus and squids normally do not produce external shell (some squid species can have an internal shell). One cephalopod group, the nau

What is the neurotransmitter of the neuromuscular junction, What is the neu...

What is the neurotransmitter of the neuromuscular junction? How does the nervous system trigger muscle contraction? The nervous cells that trigger the muscle contraction are th

Cryo preserved allografts -surgical techniques, Cry o Preserved Allograf...

Cry o Preserved Allografts (Homograft) :  As these are not mounted, a free hand suturing in two layers has to be done. The valve is thawed by protocol. The septal muscle i

Social determinants of health - social exclusion, Social Determinants of He...

Social Determinants of Health - Social Exclusion Given that absolute poverty is a major determinant of ill-health, the resultant social exclusion is ‘psychologically damaging,

Reproduction, write about asexual reproduction in mucor

write about asexual reproduction in mucor

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd