Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Q. Describe the Basic Mechanisms in Plaque Formation?
In experimental models and human disease, the first morphologic phenomenon observed in plaque formation is adhesion of monocytes to an intact endothelial surface. This adhesion is followed by monocyte migration into the intima. In the intima, monocytes are activated, converted to macrophages, and may divide. Lipid uptake by macrophages then leads to the formation of the foam cell. Many factors act in concert to cause monocyte migration to allow the incoming monocytes to establish themselves in the intima. The endothelial surface is intact in the initial phase of coronary atherosclerosis. There is no exposure of the subendothelial connective tissue matrix and therefore no adhesion of platelets to the vessel wall. Much of the cholesterol and esters in a lipid core is released from the cytoplasm of dying foam cells. Active plaques contain numerous macrophages clustered at the edge of the core with the expression of a range of metalloproteinases that likely are engaged in the active destruction of the collagen matrix.
Smooth muscle cell migration and proliferation as well as collagen deposition are driven by growth factors produced by virtually every cell type, including smooth muscle cells themselves. The normal media is a vascular, but once intimal thickening occurs, new vessels grow in from the adventitia and reach the base of the plaque.
how do birds respire while flying??
Q. Explain Percutaneous Interventions Over the last two decades, significant strides have been made in the field of Balloon Valvuloplasties both in terms of technique as well a
Define Tips that should be followed before an event Start? Before the event, following tips should be followed: As the glycogen stores may be used up during night, a h
what are chordates
Micro Debrider: long , it's tip as hand spreader, not smooth and resemble H file. - These instruments have a hedstrom cutting configuration with a standard 0.02 taper and
The citric acid cycle also called as the TCA cycle (tricarboxylic acid cycle) and the Krebs cycle or the Szent-Györgyi-Krebs cycle is a series of chemical reactions used by all aer
Phylum Ciliophora - Protozoan Simple cilia or compound ciliary organelles typical in at least one stage of life cycle; subpellicular cilia present even if surface cilia are ab
Zinc (Zn) - Micronutrients In its function in some enzyme systems, zn 2+ resembles Mn 2+ in that it brings about substrate binding and conformational changes in enzymes. A n
Why are the plants having single-seeded fruits and plants having fruits with surplus one seed? The Plants that produce single-seeded fruits, for instance, avocado and mango oft
write a note on clonning
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd