Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Q. Describe the Basic Mechanisms in Plaque Formation?
In experimental models and human disease, the first morphologic phenomenon observed in plaque formation is adhesion of monocytes to an intact endothelial surface. This adhesion is followed by monocyte migration into the intima. In the intima, monocytes are activated, converted to macrophages, and may divide. Lipid uptake by macrophages then leads to the formation of the foam cell. Many factors act in concert to cause monocyte migration to allow the incoming monocytes to establish themselves in the intima. The endothelial surface is intact in the initial phase of coronary atherosclerosis. There is no exposure of the subendothelial connective tissue matrix and therefore no adhesion of platelets to the vessel wall. Much of the cholesterol and esters in a lipid core is released from the cytoplasm of dying foam cells. Active plaques contain numerous macrophages clustered at the edge of the core with the expression of a range of metalloproteinases that likely are engaged in the active destruction of the collagen matrix.
Smooth muscle cell migration and proliferation as well as collagen deposition are driven by growth factors produced by virtually every cell type, including smooth muscle cells themselves. The normal media is a vascular, but once intimal thickening occurs, new vessels grow in from the adventitia and reach the base of the plaque.
Economic Development and Health The contribution of good health to improved growth and development prospects (or its opposite i.e. the contribution of poor health to reduced e
Cleavage - Metazoa The unicellular zygote begins cell division (cleavage). First, the single cell divides forming two cells, these redivide further to form four, then eight ce
Explain what is Cyanosis and polycythemia? Cyanosis and Polycythemia: Central cyanosis involving the mucous membranes and trunk along with the lips and extremities in absence
Define Nutritional Management of Anorexia Nervosa? The overall goal of nutritional rehabilitation of anorexia nervosa patients is to restore weight, normalize eating pattern, a
Enumerate about the Traumatic brain injuries Brain injury is a common result of automobile and industrial accidents and of war injuries. Brain injury can affect brain function
Glycerol can act as a substrate for glucose synthesis by conversion to dihydroxyacetone phosphate and an intermediate in gluconeogenesis. In order for citric acid cycle pyruva
Bohr Effect Another important influence is the pH. Increase in carbon dioxide or other acids lowers the pH of plasma and shifts the dissociation curve to the right. At high ca
Ethylene - Plant Hormones Amongst hormones in both plant and animal kingdoms, ethylene, a gaseous hydrocarbon, is unique. Despite its chemical simplicity, it is a potent growt
Structures that l pyramidenaform the r
what is the difination of osmosis
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd