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Q. How does the universality of the genetic code make the recombinant DNA technology possible?
The universality of the genetic code refers to the fact that all living beings have their protein synthesis machinery functioning according to the similar principles of storage, transmission and recognition of information, including translation of mRNA codons. This fact makes possible the exchanging of gene or genes fragments between different organisms and secures that these genes continue to command protein synthesis. This universality for instance, makes feasible the insertion of a fragment of human DNA containing a gene for the production of a given protein interested in the genetic material of bacteria. Since the bacterial translation and transcription systems work in the similar manner as the correspondent human systems do, the bacteria will begin to synthesize the human protein related to the inserted DNA fragment. There are industries that produce human insulin for use by diabetic patients in this way, synthesized by bacteria with modified DNA. If the genetic code was not universal this kind of genetic manipulating would be very difficult or impossible to accomplish without new technological progresses.
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) - These drugs are direct, non-nucleoside inhibitors of HIV-1 reverse transcriptase. Combinations of an NNRTI with NRTIs
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