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A protein that is normally a single-pass transmembrane protein is absent from the cell surface of the mutant cell line YTM-15. When labeled so that the protein can be localized, you find that this protein is now secreted by the cell. Analysis of the amino acid sequence of the transmembrane protein in question reveals sequence changes that could lead to the observed phenotype. The amino acid substitutions lead to alterations in the ER signal sequence and the stop-transfer sequence. In addition, YTM-15 cells exhibit a point mutation in the gene encoding signal peptidase. Only one mutation is consistent with the observed phenotype. What is the underlying cause of the mutant trait? Explain your reasoning.
Surgical preparation of the bone - drill technique It is essential not to allow the bone to be heated above 47°C during preparation of the site as this will cause bone cell dea
Demonstration of specific antigen(s): The presence of the viral antigen in the infected tissues and cells can be demonstrated by fluorescent antibody technique (FAT) and
how many chromosomes in human
Q. Explain the Use of nitrates and nitrites in microorganisms? The use of nitrates and nitrites has been widely used in the curing of meat. The reduction of nitrates by bacteri
Define Consistency and Texture - Dysphilgia? Aspiration of liquids, including water, into the lungs can result in complications. To avoid this problem and yet fulfilling the fl
Why is sex-linked inheritance an example of nonmendelian inheritance? The Sex-linked inheritance is a kind of nonmendelian inheritance because it opposes Mendel's first law, wh
Peptide bond formation is catalyzed by peptidyl transferase. The carboxyl end of the amino acid bound to the tRNA in this reaction and in the P site is uncoupled from the tRNA a
Availability of nutrients in soils The productivity of a crop depends largely on the nutrients discussed in the previous section. It is important to find out methods which wil
Q. Illustrate Pulmonary Artery Enlargement? On the PA view, the pulmonary trunk is border forming for a short distance between the aortic knuckle and the left atrial appendage.
Define Commodity Topics of Food Science? All issues of food science and technology of certain commodity groups, including milk and milk products (fluid milk and derivatives, ic
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