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A protein that is normally a single-pass transmembrane protein is absent from the cell surface of the mutant cell line YTM-15. When labeled so that the protein can be localized, you find that this protein is now secreted by the cell. Analysis of the amino acid sequence of the transmembrane protein in question reveals sequence changes that could lead to the observed phenotype. The amino acid substitutions lead to alterations in the ER signal sequence and the stop-transfer sequence. In addition, YTM-15 cells exhibit a point mutation in the gene encoding signal peptidase. Only one mutation is consistent with the observed phenotype. What is the underlying cause of the mutant trait? Explain your reasoning.
Q. Discovery of insulin? The discovery of insulin has dramatically changed the lives of people having type 1 diabetes. With this wonder drug diabetics can lead a normal, enjoya
how to classify the plants ?
Explain the Enriched and Living Culture Media? Enriched Media - It is used for isolation of fastidious organisms, i.e., organisms having specific and elaborate nutritional requ
State in detail about Dark Adaptation Dark adaptation is a phenomenon by which retina and pupil react to decreased illumination. Test is performed using Goldmann-Weeke's adapto
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Movement is even controlled by organelles, cilia and flagella. These and the pseudopodia in the amoebas give these small creatures movement, something we associate with animals. Es
We now understand that mutations that cause the inhibition of apoptosis are found in tumors. Because proliferation itself is not induced by the inhibition of apoptosis, explain how
Q. What is the respective importance of water, carbon and nitrogen for living beings? Water is the major solvent of living beings and it is necessary practically for all bioche
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