Demonstrate the cause of the mutant trait, Biology

Assignment Help:

A protein that is normally a single-pass transmembrane protein is absent from the cell surface of the mutant cell line YTM-15. When labeled so that the protein can be localized, you find that this protein is now secreted by the cell. Analysis of the amino acid sequence of the transmembrane protein in question reveals sequence changes that could lead to the observed phenotype. The amino acid substitutions lead to alterations in the ER signal sequence and the stop-transfer sequence. In addition, YTM-15 cells exhibit a point mutation in the gene encoding signal peptidase. Only one mutation is consistent with the observed phenotype. What is the underlying cause of the mutant trait? Explain your reasoning.


Related Discussions:- Demonstrate the cause of the mutant trait

Agro industrial-enrichment of soil, Enrichment of soil Indirect provis...

Enrichment of soil Indirect provision of minerals to grazing livestock includes mineral fertilization of  pasture and altering soil pH, however this may not be always feasible

Explain haccp system, Explain HACCP System HACCP System :  The resul...

Explain HACCP System HACCP System :  The result  of  the  implementation  of  the HACCP Plan.

What is the menstrual cycle, Q. What is the menstrual cycle? The menstr...

Q. What is the menstrual cycle? The menstrual cycle is the periodic succession of interactions between the organs and hormones of the female reproductive system after the begin

What is an immunotoxin, Immunotoxin is formed by conjugating or combining a...

Immunotoxin is formed by conjugating or combining an antibody with highly toxic agent.

Prevention of accidents - accidents and losses, Prevention of Accidents - A...

Prevention of Accidents - Accidents and Losses The theories of accident causation explained earlier serve as good guide to prevent accident. The factors that may cause acciden

What is..., What is antistaphylococcal prophylaxis and pseudomonas aerugino...

What is antistaphylococcal prophylaxis and pseudomonas aeruginosa? I''m doing a project on cystic fibrosis, and I''m curious what these terms have to do with the disease. Thanks!

Explain the general small size of arthropods, How does the presence of exos...

How does the presence of exoskeleton explain the general small size of arthropods? As they have exoskeleton and periodic ecdysis, the growth of arthropods is limited to avoid t

What do you know about tricuspid stenosis, Q. What do you know about Tricus...

Q. What do you know about Tricuspid stenosis? It is rare disease, with rheumatic etiology seen in 90 per cent of cases. In patients with rheumatic mitral stenosis only 3-5 per

Angiotensin - vertebrates, Normal 0 false false false E...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Explain the working of skeletal muscle, Explain the working of Skeletal Mus...

Explain the working of Skeletal Muscle? Skeletal muscle is under voluntary control and is responsible for voluntary movements of body parts. Skeletal muscle is also called stri

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd