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A protein that is normally a single-pass transmembrane protein is absent from the cell surface of the mutant cell line YTM-15. When labeled so that the protein can be localized, you find that this protein is now secreted by the cell. Analysis of the amino acid sequence of the transmembrane protein in question reveals sequence changes that could lead to the observed phenotype. The amino acid substitutions lead to alterations in the ER signal sequence and the stop-transfer sequence. In addition, YTM-15 cells exhibit a point mutation in the gene encoding signal peptidase. Only one mutation is consistent with the observed phenotype. What is the underlying cause of the mutant trait? Explain your reasoning.
What are the Grain boundaries Grain boundaries disrupt the motion of dislocations by a material, so reducing crystallite size is a common way to improve strength. Since grain b
Q. Can you explain Secondary Metabolites? Secondary metabolites or secondary plant products are those macromolecules that lack nitrogen and arc of restricted occurrence and the
How to grow root hairs Hairs can simply be seen on the roots of mustard seed grown on a damp flannel. Seeds placed on an earthenware dish standing in a soup plate having water
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Explain the Depletion and Repletion Studies for studying nutrient requirement? This is an experimental procedure in which volunteer subjects are kept on a diet devoid of a part
EMBO L Y - The embolic morphogenetic movements are concerned with the inward migration of prospective endodermal and mesodermal blastomeres from the external surface of blast
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