Define triglycerides and atherogenesis, Biology

Assignment Help:

Triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is likely that some of these are directly atherogenic.

Hypertriglyceridaemia is associated with alterations in the metabolism of other lipoproteins, which may explain its relationship to CHD risk. It is often inversely related to HDL such that as triglycerides increase, HDL cholesterol concentrations decrease.

In hypertriglyceridaemic individuals there is a preponderance of small, dense LDL particles. A further explanation for the link between plasma triglyceride and CHD risk relates to the association between hypertriglyceridaemia and coagulation factors. Factor VII is an important component of the extrinsic coagulation system and in prospective studies has been shown to be an independent predictor of CHD. Increasing plasma triglycerides are positively correlated with the activity of factor VII and some of the day-to-day variation in factor VII coagulation activity is related to dietary fat intake.

Plasma triglyceride concentration is also positively correlated with activity of plasminogen activator inhibitor 1 (PAI-1). PAI-1 is an inhibitor of plasminogen activation and has been shown to be increased in young myocardial infarction patients.


Related Discussions:- Define triglycerides and atherogenesis

Measures to be taken to avoid fire and in event of a fire, (a)    Bedroom ...

(a)    Bedroom :                    ·           Do not place room heaters near any inflammable materials.                  ·           Do not use heaters

Osmoregulation in protozoans, Osmoregulation in Protozoans Osmoregulat...

Osmoregulation in Protozoans Osmoregulation or water balance in protozoa is accomplished by contractile vacuoles. One to several contractile vacuoles may be present within the

Kingdom animalia, in what order did the shellfish belong? in what genus did...

in what order did the shellfish belong? in what genus did the shellfish belong? in what species did the shellfish belong?

What is the difference between facilitated and diffusion, Q. What is the di...

Q. What is the difference between facilitated and simple diffusion? Facilitated by which kind of molecule does the term "facilitated" mean? Simple diffusion is the direct passa

Sex, how to do sex ?

how to do sex ?

Male reproductive system of frog, Male reproductive system of frog: i) ...

Male reproductive system of frog: i) Testis : a) There are a pair of testis which are attached to the kidneys. b) They are oval and yellow in colour. c) Inside the testis th

Oxygen cycle, Oxygen is a major component of all living organisms. All the ...

Oxygen is a major component of all living organisms. All the organisms and plants required oxygen for aerobic respiration which they absorb from environment. Only plants release ox

Nursing process in infective endocarditis, Nursing Process Nursing Ass...

Nursing Process Nursing Assessment Health history-Past-valvular, congenital or syphilitic cardiac disease/cardiac surgery. Habits-IV drug abuse. Assess the signs an

Vitamin - a, VITAMIN - A Discovered by Macollum. Also known as ...

VITAMIN - A Discovered by Macollum. Also known as Retinol / Antixeropthalmic vitamin / Auxerophthol. It is vitamin for normal vision. It forms retinal pigments rho

Which is the brain region responsible for the coordination, Which is the br...

Which is the brain region responsible for the coordination and equilibrium of the body? In the central nervous system the cerebellum is the main controller of the motor coordin

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd