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Triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is likely that some of these are directly atherogenic.
Hypertriglyceridaemia is associated with alterations in the metabolism of other lipoproteins, which may explain its relationship to CHD risk. It is often inversely related to HDL such that as triglycerides increase, HDL cholesterol concentrations decrease.
In hypertriglyceridaemic individuals there is a preponderance of small, dense LDL particles. A further explanation for the link between plasma triglyceride and CHD risk relates to the association between hypertriglyceridaemia and coagulation factors. Factor VII is an important component of the extrinsic coagulation system and in prospective studies has been shown to be an independent predictor of CHD. Increasing plasma triglycerides are positively correlated with the activity of factor VII and some of the day-to-day variation in factor VII coagulation activity is related to dietary fat intake.
Plasma triglyceride concentration is also positively correlated with activity of plasminogen activator inhibitor 1 (PAI-1). PAI-1 is an inhibitor of plasminogen activation and has been shown to be increased in young myocardial infarction patients.
Define Protection of poly unsaturated fatty acids (PUFA) from oxidative damage? The major biological role of vitamin E is to protect PUFAs and other components of cell membrane
Subphylum Chelicerata. Six pairs of appendages, four pairs being legs, with paired chelicerae (fangs). There are three classes in this phylum.
Classification of the Phylum Protozoa up to orders
What does radial symmetry mean? What is the type of symmetry found in chordates? Which are other phyla of the animal kingdom that present species with radial symmetry? Radial
HUMA N RESPIRATORY SYSTEM -
Q. Which is the typical feature of the hookworms related to the way they obtain food and explore the host? Both The Necator americanus and Ancylostoma duodenale have mouthparts
Q. Why is AIDS difficult to prevent by vaccination? It is not easy to produce a vaccine against AIDS because the HIV is a highly mutant virus. In approximately every replicatio
This problem refers to the MN and ABO loci mentioned in class. It also refers to the Rh locus, which is responsible for the positive/negative part of the blood type. The Rh+ allele
You have 200 cells and find 120 in interphase, 57 in prophase, 8 in prometaphase, and 5 in metaphase, 8 in anaphase and 2 in telophase. (None in G0 phase). it takes 18 hours to com
in oogenesis only on functional egg cell is normally formed from primary oocyte. Briefly explain
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