Define triglycerides and atherogenesis, Biology

Assignment Help:

Triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is likely that some of these are directly atherogenic.

Hypertriglyceridaemia is associated with alterations in the metabolism of other lipoproteins, which may explain its relationship to CHD risk. It is often inversely related to HDL such that as triglycerides increase, HDL cholesterol concentrations decrease.

In hypertriglyceridaemic individuals there is a preponderance of small, dense LDL particles. A further explanation for the link between plasma triglyceride and CHD risk relates to the association between hypertriglyceridaemia and coagulation factors. Factor VII is an important component of the extrinsic coagulation system and in prospective studies has been shown to be an independent predictor of CHD. Increasing plasma triglycerides are positively correlated with the activity of factor VII and some of the day-to-day variation in factor VII coagulation activity is related to dietary fat intake.

Plasma triglyceride concentration is also positively correlated with activity of plasminogen activator inhibitor 1 (PAI-1). PAI-1 is an inhibitor of plasminogen activation and has been shown to be increased in young myocardial infarction patients.


Related Discussions:- Define triglycerides and atherogenesis

Physical environment and genetics, Physical Environment and Genetic Phy...

Physical Environment and Genetic Physical Environment : Safe water and clean air, healthy workplace, safe houses, communication and roads all contribute to good health. The

Pericardiocentesis, Pericardiocentesis It is removal of fluid form the...

Pericardiocentesis It is removal of fluid form the pericardial sac. It is a specialized procedure done n ICU or cardiac cath lab or OT. A 16 or 18 gauge needle is inserted

Define symptoms in nervous system of pernicious anaemia, Define symptoms in...

Define symptoms in Nervous system of pernicious anaemia? Parasthesia (numbness and tingling) occurs in fingers and toes.  Occasionally, there are objective signs of involvement

Explain seed gums, Seed gums Polysaccharides derived from plants and se...

Seed gums Polysaccharides derived from plants and seeds have been in use for thousand of years. Seed gums are a group of polysaccharides with the following properties: S

Blood coagulation factor - circulation, Normal 0 false false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Define discovery of other essential nutrients, Define Discovery of other Es...

Define Discovery of other Essential Nutrients? Following the identification of the food factors involved in beriberi, pellagra and scurvy, the search was on for other water-sol

Why concentration of atp is maintained in the cells, A 70-kg adult person c...

A 70-kg adult person could meet all of his/her entire energy needs for one day by consuming 3 moles of glucose (540 g)- not a highly recommended diet!. Each molecule of glucose gen

Pericarditis - nursing management, Pericarditis Nursing Management ...

Pericarditis Nursing Management Monitor-blood pressure, Pulse temperature, respiration, chills disphoresis, jugular pressure. Assess for signs of cardiac tarnponad

PROTOZOA, WHAT IS THE CLASSIFICATION OF PROTOZOA ..

WHAT IS THE CLASSIFICATION OF PROTOZOA ..

What do we mean by the term isomer, What do we mean by  the term isomer? ...

What do we mean by  the term isomer? Existence of different compounds having  same molecular form  but dtfferent structural  forms  are isomers. Monosaccharides exhibit a varie

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd