Define triglycerides and atherogenesis, Biology

Assignment Help:

Triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is likely that some of these are directly atherogenic.

Hypertriglyceridaemia is associated with alterations in the metabolism of other lipoproteins, which may explain its relationship to CHD risk. It is often inversely related to HDL such that as triglycerides increase, HDL cholesterol concentrations decrease.

In hypertriglyceridaemic individuals there is a preponderance of small, dense LDL particles. A further explanation for the link between plasma triglyceride and CHD risk relates to the association between hypertriglyceridaemia and coagulation factors. Factor VII is an important component of the extrinsic coagulation system and in prospective studies has been shown to be an independent predictor of CHD. Increasing plasma triglycerides are positively correlated with the activity of factor VII and some of the day-to-day variation in factor VII coagulation activity is related to dietary fat intake.

Plasma triglyceride concentration is also positively correlated with activity of plasminogen activator inhibitor 1 (PAI-1). PAI-1 is an inhibitor of plasminogen activation and has been shown to be increased in young myocardial infarction patients.


Related Discussions:- Define triglycerides and atherogenesis

Enumerate the number of converging developments, Enumerate the Number of co...

Enumerate the Number of converging developments These include: 1) A better definition of the unique developmental concepts that are applicable to infants and young children,

Artificial insemination, ARTIFICIAL INSEMINATION - Artificial insemi...

ARTIFICIAL INSEMINATION - Artificial insemination is a technique to make a female pregnant by artificially introducing semen into the vagina. Artificial insemination has

What is phosphorylation, Q. What is phosphorylation? What are various biolo...

Q. What is phosphorylation? What are various biological processes in which phosphorylation plays a critical role? Phosphorylation is the name given to procedure of the addition

Agro industrial-complication during gestation, Complication during gestatio...

Complication during gestation Many complications like uterine torsion, vaginal prolapse, mummification, foetal maceration, hydra allantois, hydro amnios and teratological abno

Characteristics of genetically modified foods, Normal 0 false ...

Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4

Describe the part of the female reproductive system, Q. What is the part of...

Q. What is the part of the female reproductive system where fecundation occurs? Fecundation in general occurs in the Fallopian tubes but it can also take place within the uteru

What are the types of antigenic agents, Q. What are the types of antigenic ...

Q. What are the types of antigenic agents that may constitute vaccines? Vaccines can be constituted of dead agents of disease, of inactivated toxins, of inactivated agents of d

Explain the gomez classification, Explain the Gomez classification? It ...

Explain the Gomez classification? It will be of interest to you to learn that in Mexico, a child specialist named Gomez and his co-workers proposed a classification expressing

Typological species concept, The typological species concept was suggested ...

The typological species concept was suggested by Plato more than 2000 years ago. According to this concept, the immense variety in nature can be reduced to a few "types". Individua

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd