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Triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is likely that some of these are directly atherogenic.
Hypertriglyceridaemia is associated with alterations in the metabolism of other lipoproteins, which may explain its relationship to CHD risk. It is often inversely related to HDL such that as triglycerides increase, HDL cholesterol concentrations decrease.
In hypertriglyceridaemic individuals there is a preponderance of small, dense LDL particles. A further explanation for the link between plasma triglyceride and CHD risk relates to the association between hypertriglyceridaemia and coagulation factors. Factor VII is an important component of the extrinsic coagulation system and in prospective studies has been shown to be an independent predictor of CHD. Increasing plasma triglycerides are positively correlated with the activity of factor VII and some of the day-to-day variation in factor VII coagulation activity is related to dietary fat intake.
Plasma triglyceride concentration is also positively correlated with activity of plasminogen activator inhibitor 1 (PAI-1). PAI-1 is an inhibitor of plasminogen activation and has been shown to be increased in young myocardial infarction patients.
Q. How to investigate mitral regurgitation by Chest Radiogram? Enlarged left atrium is obvious on chest X-ray and it may occupy most of the cardiac silhouette in patients with
After the virus capsid containing vimentin gets into the nucleus it is broken down and the DNA is released. Whether capsid proteins are broken down into amino acids or remain intac
Define Requirements of Carbohydrates during Surgery? Carbohydrates: Carbohydrates are needed to build up glycogen stores and spare the proteins for tissue synthesis, Around GO%
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Why Vegetable and Fruit are important for human body? The vegetables and fruits add colour and variety to our diets in addition to providing a host of essential nutrients and p
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Determine some assessment measures of Zinc? Measurement of zinc in plasma: This is the most common method. Fasting concentrations of less than 70 μg/litre suggests deficie
This means the non-market value of natural products such as firewood, game and fodder that do not pass through a market or product preparation. Indigenous people in developing cou
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