Define triglycerides and atherogenesis, Biology

Assignment Help:

Triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is likely that some of these are directly atherogenic.

Hypertriglyceridaemia is associated with alterations in the metabolism of other lipoproteins, which may explain its relationship to CHD risk. It is often inversely related to HDL such that as triglycerides increase, HDL cholesterol concentrations decrease.

In hypertriglyceridaemic individuals there is a preponderance of small, dense LDL particles. A further explanation for the link between plasma triglyceride and CHD risk relates to the association between hypertriglyceridaemia and coagulation factors. Factor VII is an important component of the extrinsic coagulation system and in prospective studies has been shown to be an independent predictor of CHD. Increasing plasma triglycerides are positively correlated with the activity of factor VII and some of the day-to-day variation in factor VII coagulation activity is related to dietary fat intake.

Plasma triglyceride concentration is also positively correlated with activity of plasminogen activator inhibitor 1 (PAI-1). PAI-1 is an inhibitor of plasminogen activation and has been shown to be increased in young myocardial infarction patients.


Related Discussions:- Define triglycerides and atherogenesis

Determine the importance of calcium in soils, Determine the importance of C...

Determine the importance of Calcium in soils Calcium in soils is usually abundant except in acid soils, which occur in humid areas due to excessive leaching. Deficiency of calc

Zoonotic diseases-classification in terms of reservoir host, Classification...

Classification in terms of reservoir host 1.  Anthropozoonoses: Infections transmitted from lower vertebrate to man, e.g., rabies, plague, leptospirosis, etc. 2.   Zooanthro

Explain the term microfilaments, Explain the term Microfilaments ? Mi...

Explain the term Microfilaments ? Microfilaments are fine fibrils, only 7 nm in diameter, composed of a protein called actin. Actin is one of the two major proteins involved

What is photosynthesis , What is Photosynthesis ? Photosynthesis is t...

What is Photosynthesis ? Photosynthesis is the method by which plants trap radiant energy from the sun and convert the energy into a biochemical form. This biochemical energy

Why d scientists pick hydrogen as the basis for mri scanning, Why d scienti...

Why d scientists pick hydrogen as the basis for MRI scanning? Name of the human body that do not appear in an MRI scan. Explain thermal stratification? How does thermal stratifi

Explain about skeletal muscle, Explain about Skeletal muscle These are ...

Explain about Skeletal muscle These are attached to the bones by tendons, which help in the movement of the part of the skeleton. These muscles are controlled by our conscious

What is the typical localization of the tropical forests, What is the typic...

What is the typical localization of the tropical forests regarding latitude? The Tropical rain forests, like the Congo forest and the Amazon forest, are typically located in lo

Mutual supplementation of protein with legume and milk, Define Mutual suppl...

Define Mutual supplementation of Protein with legume and milk? Improvement of cereal diets with legume and milk proteins: The proteins of poor diets based on different cereals

Describe valsalva manocuvre in dynamic auscultation, Describe Valsalva Mano...

Describe Valsalva Manocuvre in dynamic auscultation ? This consists of deep inspiration followed by forced inhalation against a closed glottis for 10-20 seconds. It can be perf

Can you explain puffeelfish poisoning, Q. Can you explain Puffeelfish poiso...

Q. Can you explain Puffeelfish poisoning? Tetrodotoxin (TTX) causes pufferfish (tetrodon) poisoning, also known as blowfish poisoning or fugu. How does a pufferfish look l

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd