Define triglycerides and atherogenesis, Biology

Assignment Help:

Triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is likely that some of these are directly atherogenic.

Hypertriglyceridaemia is associated with alterations in the metabolism of other lipoproteins, which may explain its relationship to CHD risk. It is often inversely related to HDL such that as triglycerides increase, HDL cholesterol concentrations decrease.

In hypertriglyceridaemic individuals there is a preponderance of small, dense LDL particles. A further explanation for the link between plasma triglyceride and CHD risk relates to the association between hypertriglyceridaemia and coagulation factors. Factor VII is an important component of the extrinsic coagulation system and in prospective studies has been shown to be an independent predictor of CHD. Increasing plasma triglycerides are positively correlated with the activity of factor VII and some of the day-to-day variation in factor VII coagulation activity is related to dietary fat intake.

Plasma triglyceride concentration is also positively correlated with activity of plasminogen activator inhibitor 1 (PAI-1). PAI-1 is an inhibitor of plasminogen activation and has been shown to be increased in young myocardial infarction patients.


Related Discussions:- Define triglycerides and atherogenesis

Acid rain, What direct or indirect effect is acid rain thought to have on m...

What direct or indirect effect is acid rain thought to have on mama''s and forest and buildings

Endocrine glands - placenta, PLACEN T A - Placenta is the intimate...

PLACEN T A - Placenta is the intimate connection between the foehls and the uterine wall of the mother to exchange the materials. Placenta is a tempormy endocrine gland

Carbon dioxide for photosynthesis, Aim: To prove that Carbon dioxide is ess...

Aim: To prove that Carbon dioxide is essential for photosynthesis. Apparatus: A potted healthy plant with long and narrow leaves, a wide mouthed glass bottle, split cork. Chemicals

Cultural and religious values, Wildlife has influenced language, art, relig...

Wildlife has influenced language, art, religion and social customs of many societies worldwide, and wild animals figure prominently in many cultures even today. In all cultures of

Bovine ephemeral fever, B o v i ne ephemeral fever Ephemeral fever ...

B o v i ne ephemeral fever Ephemeral fever is commonly known as 'three-day sickness'. It affects mainly cattle and occasionally sheep in India. Causative agent is a mosquit

Explain some effect of inadequate nutrition, Explain some Effect of Inadequ...

Explain some Effect of Inadequate nutrition? Inadequate nutrition ranks as one of the major problems of old age. Various factors which may be responsible for the change in one

Nerve fibres, NERV E FIBRES - Axon or dendrite of a nerve cell cove...

NERV E FIBRES - Axon or dendrite of a nerve cell covered with one, two or three sheaths is called nerve fibre. Dendrites are surrounded only by one sheath. An axon may b

Hazards in biology laboratory, The major hazards encountered in the biologi...

The major hazards encountered in the biological lab work are diseases like infections and allergies which are caused by handling live animals. dissections, plant and animal tissues

Explain food applications of xanthan, Explain Food Applications of xanthan ...

Explain Food Applications of xanthan Xanthan gum is mainly considered to be non-gelling and used for the control of viscosity due to the tenuous associations, endowing it w

The fragility of erythrocytes, The fragility of erythrocytes The fragil...

The fragility of erythrocytes The fragility of erythrocytes is impaired in the absence of NADPH generation due to the deficiency of glucose-6-phosphate dehydrogenase thereby ca

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd