Define triglycerides and atherogenesis, Biology

Assignment Help:

Triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is likely that some of these are directly atherogenic.

Hypertriglyceridaemia is associated with alterations in the metabolism of other lipoproteins, which may explain its relationship to CHD risk. It is often inversely related to HDL such that as triglycerides increase, HDL cholesterol concentrations decrease.

In hypertriglyceridaemic individuals there is a preponderance of small, dense LDL particles. A further explanation for the link between plasma triglyceride and CHD risk relates to the association between hypertriglyceridaemia and coagulation factors. Factor VII is an important component of the extrinsic coagulation system and in prospective studies has been shown to be an independent predictor of CHD. Increasing plasma triglycerides are positively correlated with the activity of factor VII and some of the day-to-day variation in factor VII coagulation activity is related to dietary fat intake.

Plasma triglyceride concentration is also positively correlated with activity of plasminogen activator inhibitor 1 (PAI-1). PAI-1 is an inhibitor of plasminogen activation and has been shown to be increased in young myocardial infarction patients.


Related Discussions:- Define triglycerides and atherogenesis

What is mitral valve and coronary arteries, Q. What is Mitral Valve and Cor...

Q. What is Mitral Valve and Coronary Arteries? On the PA view, mitral valve calcification is seen just to the left of the spine, below the position of the aortic valve. The lar

Main opportunistic diseases that can affect aids patients, Q. What are the ...

Q. What are the main opportunistic diseases that can affect AIDS patients? Among the opportunistic diseases that affect HIV contaminated people during the AIDS stage some are:

Amphibia, what should i write in conclusion

what should i write in conclusion

What is the importance of uterine glycogen-producing glands, What is the im...

What is the importance of the uterine glycogen-producing glands? The uterine glands produce glycogen that can be degraded into glucose to nourish the embryo before the complete

ALGAE., HOW ARE THE ORIGIN AND EVOLUTION OF ALGAE..

HOW ARE THE ORIGIN AND EVOLUTION OF ALGAE..

When the plant transpiration increases, When air humidity is high does the ...

When air humidity is high does the plant transpiration increase or lower? When air humidity is high transpiration diminishes. As transpiration is a simple diffusion process it

Explain about non ionising radiation, Q. Explain about Non ionising radiati...

Q. Explain about Non ionising radiation? Non ionising radiation include infrared and UV rays. Lethal effect is through generation of heat and DNA damage. Penetration is low but

What is sustainability, What is sustainability? Sustainability is the a...

What is sustainability? Sustainability is the ability to meet human needsin a way that will allow a human population to survive indefinitely.

Anaplasia - characteristics define cancer, Anaplasia - Characteristics Defi...

Anaplasia - Characteristics Define Cancer Anaplasia is a structural abnormality where cells resemble primitive or embryonic tissue in which adult functions are diminished or t

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd