Define triglycerides and atherogenesis, Biology

Assignment Help:

Triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is likely that some of these are directly atherogenic.

Hypertriglyceridaemia is associated with alterations in the metabolism of other lipoproteins, which may explain its relationship to CHD risk. It is often inversely related to HDL such that as triglycerides increase, HDL cholesterol concentrations decrease.

In hypertriglyceridaemic individuals there is a preponderance of small, dense LDL particles. A further explanation for the link between plasma triglyceride and CHD risk relates to the association between hypertriglyceridaemia and coagulation factors. Factor VII is an important component of the extrinsic coagulation system and in prospective studies has been shown to be an independent predictor of CHD. Increasing plasma triglycerides are positively correlated with the activity of factor VII and some of the day-to-day variation in factor VII coagulation activity is related to dietary fat intake.

Plasma triglyceride concentration is also positively correlated with activity of plasminogen activator inhibitor 1 (PAI-1). PAI-1 is an inhibitor of plasminogen activation and has been shown to be increased in young myocardial infarction patients.


Related Discussions:- Define triglycerides and atherogenesis

Respiratory organ in animals, RESPIR A T ORY ORGANS IN ANIMALS - ...

RESPIR A T ORY ORGANS IN ANIMALS - In Protozoa plasmalemma functions as respiratory surface. In Porifera, respiration occur through body wall. In Coelentrata resp

Are plant growth is depend on the plant harmones, Are the growth and develo...

Are the growth and development of plants only influenced by plant hormones? Chemical and Physical environmental factors, like position and intensity of light in relation to the

What is digestion, What is digestion? Digestion is the breaking down of...

What is digestion? Digestion is the breaking down of larger organic molecules obtained from the diet, e.g. carbohydrates, fats, proteins, into smaller ones, as glucose, fatty a

How are sponges characterized, Q Sponge identity card. How are sponges char...

Q Sponge identity card. How are sponges characterized according to example of representing beings, basic morphology, type of symmetry, embryonic (germ) layers and coelom, digestive

What are the catalysts, Q. What are the catalysts? Catalysts are substa...

Q. What are the catalysts? Catalysts are substances that decrease the activation energy of a chemical reaction, facilitating it or making it energetically viable. The catalyst

Management goals for diverticular disease, Q. Management goals for divertic...

Q. Management goals for diverticular disease? The management goals discussed above are basic to prevention of diverticulitis. However, diet therapy during diverticulitis may b

What are plant cell vacuoles, What are plant cell vacuoles? What are their ...

What are plant cell vacuoles? What are their functions? How is the covering membrane of the vacuoles called? Ans) Plant cell vacuoles are cell structures delimited by membranes

Components of treatment of nkhdc, The components of treatment of NKHDC are:...

The components of treatment of NKHDC are: 1) control of water loss. 2) control of sugar using insulin. 3) adjust electrolytes like sodium and potassium. 4) control infe

What is physiologically corrected transposition of arteries, What is Physio...

What is Physiologically corrected transposition of arteries? Physiologically corrected Transposition of the great arteries (ZTGA): Atrio- ventricular connections are also inapp

Relationship between mind and brain, Q. Relationship between Mind and Brain...

Q. Relationship between Mind and Brain? In modern times, before the 20th century, the most popular interpretation of the mind-brain relationship was some version of dualism. It

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd