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Triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is likely that some of these are directly atherogenic.
Hypertriglyceridaemia is associated with alterations in the metabolism of other lipoproteins, which may explain its relationship to CHD risk. It is often inversely related to HDL such that as triglycerides increase, HDL cholesterol concentrations decrease.
In hypertriglyceridaemic individuals there is a preponderance of small, dense LDL particles. A further explanation for the link between plasma triglyceride and CHD risk relates to the association between hypertriglyceridaemia and coagulation factors. Factor VII is an important component of the extrinsic coagulation system and in prospective studies has been shown to be an independent predictor of CHD. Increasing plasma triglycerides are positively correlated with the activity of factor VII and some of the day-to-day variation in factor VII coagulation activity is related to dietary fat intake.
Plasma triglyceride concentration is also positively correlated with activity of plasminogen activator inhibitor 1 (PAI-1). PAI-1 is an inhibitor of plasminogen activation and has been shown to be increased in young myocardial infarction patients.
Plot the amount of DNA in the nucleus of a spermatogonia from the G1 stage prior to the first meiotic division through the completion of meiosis. Label each of the major stages of
Acute Aortic Regurgitation : The most dramatic presentation occurs in dissection of the aortic root. Endocarditis of the native or prosthetic aortic valve may also lead to a
Q. What is Gastritis? Gastritis is an inflammatory lesion of the gastric mucosa, (the inner lining of the stomach). The problem is seen in two forms: a) Acute gastritis
a) What is biological magnification? b) Describe how DDT as a water pollutant undergoes biological magnification?
transport systerms
in molluscathe foot is used for (capturing locomotion or both
Vascular Cambium The vascular cambium usually, if not always, has a dual origin within the primary tissues; from provascular strands, and from the "ground" meristem tissues be
Give two examples in each case of organs or tissues in which you would expect (a) meiosis, (b) mitosis to be taking place a) Meiosis is likely to
Define Assessment of iron status - Haemoglobin and Haematocrit? In the final stages of iron deficiency, anaemia occurs. Haemoglobin and Haematocrit levels indicate prevalence o
You have 875 mL of a 0.37 M acetic acid solution. What volume (V) of 1.20 M NaOH solution must you add in order to prepare an acetate buffer of pH = 4.36? (The pKa of acetic acid i
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