Define triglycerides and atherogenesis, Biology

Assignment Help:

Triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is likely that some of these are directly atherogenic.

Hypertriglyceridaemia is associated with alterations in the metabolism of other lipoproteins, which may explain its relationship to CHD risk. It is often inversely related to HDL such that as triglycerides increase, HDL cholesterol concentrations decrease.

In hypertriglyceridaemic individuals there is a preponderance of small, dense LDL particles. A further explanation for the link between plasma triglyceride and CHD risk relates to the association between hypertriglyceridaemia and coagulation factors. Factor VII is an important component of the extrinsic coagulation system and in prospective studies has been shown to be an independent predictor of CHD. Increasing plasma triglycerides are positively correlated with the activity of factor VII and some of the day-to-day variation in factor VII coagulation activity is related to dietary fat intake.

Plasma triglyceride concentration is also positively correlated with activity of plasminogen activator inhibitor 1 (PAI-1). PAI-1 is an inhibitor of plasminogen activation and has been shown to be increased in young myocardial infarction patients.


Related Discussions:- Define triglycerides and atherogenesis

Buffalo-pox, Buffalo-pox The disease is caused by an orthopox virus, c...

Buffalo-pox The disease is caused by an orthopox virus, closely related to the vaccinia virus. It is not clear whether it should be considered a separate virus or not. By RE m

Nutrition project, what websites can i use to modify my client''s meals?

what websites can i use to modify my client''s meals?

Standard invert sugar solution, Q. Standard invert sugar solution? Rea...

Q. Standard invert sugar solution? Reagents Required 1) Standard invert sugar solution: Weigh accurately 0.985 g of sucrose and dissolve in 500 ml of water. Add 2 ml of

Define ecosystems science and large-scale ecology, Define Ecosystems scienc...

Define Ecosystems science and large-scale ecology? Many of today's most pressing problems are regional or global in nature including for instance, the effects of land cover and

Zoology, right classification of protozoa up to class

right classification of protozoa up to class

Discuss in brief distant and contact osteogenesis, Q. Discuss in brief dist...

Q. Discuss in brief distant and contact osteogenesis? Three terms are used to describe individual aspects of bone formation process that occur at implants. They are Osteocondu

Tumor suppressor genes, Tumor Suppressor Genes Tumor suppressor genes...

Tumor Suppressor Genes Tumor suppressor genes or anti-oncogenes generally inhibit cell division in cooperation with proto-oncogenes. The very existence of these genes prevent

Explain angiosperms and flowering plants, Q. What are the angiosperms, the ...

Q. What are the angiosperms, the flowering plants? What is the major feature that distinguishes them from the gymnosperms? Flowering plants have seeds and flowers (phanerogamic

Determine the fructose to glucose ratio in honey, Q. Determine the fructose...

Q. Determine the fructose to glucose ratio in honey? This activity will help you to: • check the given samples of honey for any adulteration with commercial sugar

What are the functional divisions of the nervous system, What are the funct...

What are the functional divisions of the nervous system? Functionally the nervous system can be separated into the somatic nervous system and visceral nervous system. The so

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd