Define triglycerides and atherogenesis, Biology

Assignment Help:

Triglyceride accumulation is not a feature of the atherosclerotic plaque but triglyceride-rich lipoproteins also contain cholesterol esters and it is likely that some of these are directly atherogenic.

Hypertriglyceridaemia is associated with alterations in the metabolism of other lipoproteins, which may explain its relationship to CHD risk. It is often inversely related to HDL such that as triglycerides increase, HDL cholesterol concentrations decrease.

In hypertriglyceridaemic individuals there is a preponderance of small, dense LDL particles. A further explanation for the link between plasma triglyceride and CHD risk relates to the association between hypertriglyceridaemia and coagulation factors. Factor VII is an important component of the extrinsic coagulation system and in prospective studies has been shown to be an independent predictor of CHD. Increasing plasma triglycerides are positively correlated with the activity of factor VII and some of the day-to-day variation in factor VII coagulation activity is related to dietary fat intake.

Plasma triglyceride concentration is also positively correlated with activity of plasminogen activator inhibitor 1 (PAI-1). PAI-1 is an inhibitor of plasminogen activation and has been shown to be increased in young myocardial infarction patients.


Related Discussions:- Define triglycerides and atherogenesis

Aim of diabetes counselling, Aim of Diabetes Counselling Diabetes is a...

Aim of Diabetes Counselling Diabetes is a life-long illness. Diagnosis of diabetes has psychological and physical implications. Preventive counselling and life style change ca

Define factors influencing rs content of foods, Define Factors Influencing ...

Define Factors Influencing RS Content of Foods? Different fractions of RS mentioned in Table may be naturally present in some foods or may be generated as a result of industria

Reed-swamp stage - hydrarch, Reed-Swamp Stage - Hydrarch This stage is...

Reed-Swamp Stage - Hydrarch This stage is also known as amphibious stage, as the plants of the community are rooted but most parts of their shoots remain exposed to air. Speci

Onion cells, What is the process of mitosis in onion root tips in a lab

What is the process of mitosis in onion root tips in a lab

Define can we improve the nutritive value of protein, Define Can we improve...

Define Can we improve the nutritive value of protein? Yes, as discussed above, the nutritive value of a protein can be improved in two ways: (1) by mutual supplementation, that

Formulate a specific hypothesis, A professor wonders whether good study hab...

A professor wonders whether good study habits lead to better grades in the final exam. Formulate a specific hypothesis and then design an experiment to test it. In your answer outl

Who could be the parents of a child, This problem refers to the MN and ABO ...

This problem refers to the MN and ABO loci mentioned in class. It also refers to the Rh locus, which is responsible for the positive/negative part of the blood type. The Rh+ allele

Types of forests - ecosystem, Types of Forests - Ecosystem The forest ...

Types of Forests - Ecosystem The forest biomes of the world have been classified into the three major categories: coniferous forest, tropical forest and temperate forest. C

Signs and symptoms of hypoglycaemia, Q. Signs and Symptoms of Hypoglycaemia...

Q. Signs and Symptoms of Hypoglycaemia? Let us now learn about signs and symptoms of hypoglycaemia. It is important for you know these because you can help the patient and fami

How can total count can be obtained?, How Can Total Count Can Be Obtained? ...

How Can Total Count Can Be Obtained? Total count can be obtained microscopically by using fluorescent dyes such as acridine orange or DNA stain DAPI. The counts obtained micros

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd