Which of the following statements regarding the interactions among sequence-specific DNA binding domains and their recognition sites is incorrect?

A. Sequence-specific DNA binding domains use alpha helical structures to interact with nucleotides within the main groove.

B. Multiple sequence-specific developmentally regulated DNA binding proteins can concurrently bind to an enhancer element.

C. The quality of the binding site will influence both the residency time of a DNA binding protein at the enhancer and the level of transcriptional output from the enhancer.

D. Sequence-specific DNA binding proteins recruit RNA Pol II to the enhancer element.