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Define the LTLT Pasteurization Method?
In LTLT pasteurization, the pasteurization time is in the order of minutes and related to the temperature used; two typical temperature/time combinations are used: 63 to 65°C over 30 minutes or 75° C over 8 to 10 minutes.
In this first class of pasteurization processes it is probable to define three phases:
a) Heating to a fixed temperature;
b) Keeping this temperature over the established time period (= pasteurization time);
c) Cooling the pasteurized products: natural (slow) or forced cooling.
You would notice that, pasteurization temperature and time will vary according to:
a) Nature of product; initial degree of contamination;
b) Pasteurized product storage conditions and shelf life required.
Main successful vaccines are live attenuated and heat killed vaccines.
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