Define the Effect of Wernicke korsakoff syndrome?

Besides occurring in infants, beriberi also occurs in adults with high carbohydrate intakes (mainly from milled rice) and with intakes of anti-thiamin factors, such as the bacterial thiaminases that are in certain ingested raw fish. Beriberi is still endemic in Asia. In relatively industrialized nations, the neurologic manifestations of Wernicke korsakoff syndrome are often related with chronic alcoholism in conjunction with limited food consumption. Some cases of thiamin deficiency have been observeci with patients who are hypermetabolic, are on parenteral nutrition, are undergoing chronic renal dialysis, or have undergone a gastrectomy. Thiamin deficiency has also been observed in people with chronic alcoholism.