Define some adverse effects of saponins, Biology

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Define some adverse effects of saponins?

The adverse effects of saponins may be described as under:

- A well-known toxic effect is 'erythrocyte lysis' since they interact with the cholesterol in the erythrocyte membrane.

- In mammals, intravenous administration causes local inflammation.

- In large doses, it results in death due to massive release of erthyrocyte debris.

 - A reduction in oxygen-carrying capacity of blood.

 - It can lyse other cells e.g. of the intestinal mucosa and thus affect nutrient absorption.

- High saponin intake results in decreased weight gain.


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