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Define role of Leptin in controlling gene expression?
Leptin is a protein product (containing 167 amino acids) of the ob gene expressed exclusively in the adipose tissue. This protein molecule functions as an afferent signal in a negative feedback loop, centred in the hypothalamus, regulating the size of the adipose tissue mass.Leptin has been shown to modulate the synthesis of neuropeptides, particularly Neuropeptide Y (NPY) that regulates food intake. Increases energy expenditure as indicated by animal experiments. Leptin induced weight loss is completely specific for adipose tissue. While feeding does not appear to modulate leptin expression, fasting acutely decreases plasma leptin concentration. In general, obese humans have high leptin levels and the available data suggest that human obesity is likely to be associated with insensitivity to leptin.
List the advantages and disadvantages of stage 2 surgery using a tissue punch. Advantages - Less traumatic to surrounding tissue - Faster progress to the impression proce
Q. Can High blood pressure cause coronary sclerosis? High blood pressure causes coronary sclerosis (hardening in early stages, fatty lesions in the inner surface of [he artery
In Chemical Reactions that have a large negative /\Go' a- the total amount of both reactants and products decreases b- the products are less stable than the reactants c- t
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State the term - Halsted Reitan varies with the particular test Scoring for the Halsted Reitan varies with the particular test, such that individual scores may be expressed in
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Q. What are some prophylactic measures against HIV infection? The major prophylactic measures against HIV infection are: the use of condoms in sexual relations, not to share ne
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