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Define role of Leptin in controlling gene expression?
Leptin is a protein product (containing 167 amino acids) of the ob gene expressed exclusively in the adipose tissue. This protein molecule functions as an afferent signal in a negative feedback loop, centred in the hypothalamus, regulating the size of the adipose tissue mass.Leptin has been shown to modulate the synthesis of neuropeptides, particularly Neuropeptide Y (NPY) that regulates food intake. Increases energy expenditure as indicated by animal experiments. Leptin induced weight loss is completely specific for adipose tissue. While feeding does not appear to modulate leptin expression, fasting acutely decreases plasma leptin concentration. In general, obese humans have high leptin levels and the available data suggest that human obesity is likely to be associated with insensitivity to leptin.
Q. What do you mean by ST-Segment in Exercise Induced PVC? Ans. Over the years it has been believed that repolarization in ventricular ectopic beats had no diagnostic si
Insulin Pump An insulin pump is a device used for the administration of insulin, also known as continuous subcutaneous insulin infusion therapy. The device includes: - the
How vitamin e is directly related to Vitamins A, D and K? A high intake of vitamin E interferes with the functions of other fat-soluble vitamins such as vitamin K absorpt
Food Applications of Locust bean gum Locust bean gum has multiple applications in food industry. Let us focus on a few of the important ones: Locust bean gum has been u
Demonstrate the structure of mitochondria The structure of mitochondria has been examined in great detail with the aid of the electron microscope, and it is now possible to des
How do homeotic genes regulate development in Drosophila? Homeotic genes code for regulatory proteins that are thought to control the rate of cell division in various body area
What is Cyanosis ? Cyanosis: Cyanosis may be peripheral or central. Peripheral cyanosis almost exclusively involves lips and extremities. Normal neonates may have bluish extrem
Q. Pathophysiology of Tricuspid regurgitation? Tricuspid regurgitation is associated with prominent venous filling waves and elevated right atrial venous pressures. Hepatic and
Define Principle for Determination of Blood Glucose by Nelson Somogyi Method? Proteins are precipitated from the sample and protein free filtrate is heated with alkaline copper
Cleft Palate Well you have now learnt about the cleft lip and now let us discuss and understand what is cleft palate. Cleft palate (CP) is midline fissure of the palate that
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