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Modulation of the transcription of cell cycle proteins?
The 1,25-(OH),D compound (calcitriol), is present in the blood complexes to the vitamin D-binding protein, a specific a-globulin. Calcitriol is believed to act on target cells in a similar way to a steroid hormone. Free hormone crosses the plasma membrane and interacts with a specific nuclear receptor known as the vitamin D receptor, a DNA-binding, zinc-finger protein with a relative molecular mass of 55,000. This ligand-receptor complex binds to a specific vitamin D-responsive element and, with associated transcription factors (e.g. retinoid X receptor), enhances transcription of mRNAs which code for calcium-transporting proteins, bone matrix proteins, or cell cycle-regulating proteins.
Explain Arthritis Arthritis - Oral therapy with doxycycline or amoxicillin for 28 days is usually effective for treatment of Lyme arthritis. Patients who have not responded to
Classification of Diabetes Mellitus a) Type1Diabetes Mellitus i) Type 1 a ii) Type 1 b b) Type 2 Diabetes Mellitus c) Others i) Gestational Diabetes Mellitus
Q. Pathology of mitral regurgitation? During left ventricular systole as the pressure rises in left ventricle, blood is pumped simultaneously both into aorta and left atrium. T
Structure of the Vascular Cambium This meristem, in the anatomical sense of the term usually includes two histologically distinct kinds of cells: i) Fusiform Initials, i
How do I write the expression for reaction rate (transport) of species between the arterial compartment and the other tissue compartments in symbiology?
The response produced when an allergen is injected into an individual, who is sensitive is known as P-K reaction.
Q. Use of Aldehydes as chemical sterilant? Formaldehyde: widely employed for the fumigation of operation theatres. Glutaraldehyde: commercial preparations are active at
Tricuspid Valve Replacement : It is done for organic tricuspid valve disease and at times for functional tricuspid I regurgitation. When done along with other procedures, it
Define Important Points While Working With Autoclave? Note: Following points should be kept in mind while working with autoclave. 1. Autoclave should not be packed tightly o
Q. How different are the concepts of migration, emigration and immigration? The Migration is the moving of individuals of a species from one place to another. The Emigration is
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