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Modulation of the transcription of cell cycle proteins?
The 1,25-(OH),D compound (calcitriol), is present in the blood complexes to the vitamin D-binding protein, a specific a-globulin. Calcitriol is believed to act on target cells in a similar way to a steroid hormone. Free hormone crosses the plasma membrane and interacts with a specific nuclear receptor known as the vitamin D receptor, a DNA-binding, zinc-finger protein with a relative molecular mass of 55,000. This ligand-receptor complex binds to a specific vitamin D-responsive element and, with associated transcription factors (e.g. retinoid X receptor), enhances transcription of mRNAs which code for calcium-transporting proteins, bone matrix proteins, or cell cycle-regulating proteins.
Define Clinical Trials for Changing nutrient requirements with age? Several clinical trials provide evidence of changing nutrient requirements with age. The metabolic demand fo
Omnispective Classification This is the extension of the concept of natural classification put forward by Black Welder (1967). The approach seems quite realistic and pragmatic.
What is the main cell organelle involved in cell digestion? What are the properties of that organelle that enable it to do the task? The organelles responsible for intracellula
It is found in around 20 per cent cases of ARF and it is a late manifestation occurring even 3 months after GAS pharyngeal infection. Chorea is triggered by emotional disturbances
Control of Pollution We have seen that pollution affects human health, 'vegetation, crop yield, trees, fisheries, forests, buildings, archaeological monuments, tourism. These
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Q. What is the parasite that causes toxoplasmosis? How is the disease transmitted and what are its typical manifestations? The Toxoplasmosis is caused by the protozoan Toxoplas
GROWT H CURVES - S-shaped or sigmoid - Described by Verhuhst in 1839. It shows 5 phases - (i) Lag phase (ii) Positive acceleration phase (iii) Exponent
Social Determinants of Health - Unemployment That unemployment gives rise to social insecurity and psychological stress is well recognised. Fears and uncertainties are known t
What is the difference between the concepts of food chain and food web? The chain method is a theoretical model to study the energy flux in ecosystems. Actually in an ecosystem
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