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Modulation of the transcription of cell cycle proteins?
The 1,25-(OH),D compound (calcitriol), is present in the blood complexes to the vitamin D-binding protein, a specific a-globulin. Calcitriol is believed to act on target cells in a similar way to a steroid hormone. Free hormone crosses the plasma membrane and interacts with a specific nuclear receptor known as the vitamin D receptor, a DNA-binding, zinc-finger protein with a relative molecular mass of 55,000. This ligand-receptor complex binds to a specific vitamin D-responsive element and, with associated transcription factors (e.g. retinoid X receptor), enhances transcription of mRNAs which code for calcium-transporting proteins, bone matrix proteins, or cell cycle-regulating proteins.
How can the knowledge about fermentation explain the origin of muscle cramps and pains after intense physical exertion? A typical fermentation process because of oxygen scarcit
Q. Symptoms of inflammatory bowel disease? Inflammatory bowel diseases are associated with: • Abdominal cramping, diarrhoea • Steatorrhoea • Obstruction caused due t
Explain about the Invert sugar? Invert sugar is sucrose, which can be hydrolysed to split the disaccharide into its component sugars, fructose and glucose. It is known as inver
Materials Handling and Storage Material handling is a very significant process in working place. The materials are handled in not finished, semi finished and finished states.
Where does most of the water resorbed after glomerular filtration go? What are the other substances resorbed by the nephron tubules? Only 0.5 to 1% of the glomerular filtrate i
Elaborate the term - Gill slits. Lateral opening in the wall of pharynx which allows water to enter into mouth and exit through the pharynx. This is one of the ancestral charac
Post-partum anoestrus Reproductive efficiency among animals greatly depends upon detection of estrus. This is even more important in reference to small herds managed under tro
what is the classification of protozoa
Gelation Agar gels can be formed in very dilute solutions containing a fraction of 1% agar. In fact gelation is perceptible at concentrations as low as 0.04%. These gels are ri
Explain Non-surgical Endodontic Retreatment - Missed Canal Missed root canal as it hold pulp tissues and bacteria is major cause of endodontic failure. Mandibular molar
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