Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Define Mobilization of bone calcium and phosphorous?
It is now firmly established that vitamin D3 is metabloized first in the liver to 25-hydroxyvitamin D (25 OH- D) (calcicliol) and subsequently in the kidneys to I. 25 dihydroxycholecalciferol or 1.25 (OH)2 D (calcitriol to produce a biological active hormone. The functions of vitamin D are mediated by this vital vitamin D hormone by a homeostatic mechanism which involves the hormone acting on the intestines kidney and bone to increase serum calcium and phosphorus levels. 1.25 (OH)2D stimulates intestinal absorption of calcium and phosphate and mobilized calcium and phosphate by stimulating bone resorption. The functions serve the common purpose of rstnring blood levels of calcium and phosphate to normal when concentrations of the two ions are low. This helps to achieve a normal blood calcium concentration and maintenance of calcium homeostasis.
In calcium homeostasis, 1, 25-(OH) D works in conjunction with pa athyroid hormone (PTH) to produce its beneficial effects on the plasma levels of ionized calcium and phosphate. The physiologic loop starts with the calcium receptor of the parathyroid gland. When the level of ionized calcium in plasma falls, PTH is secreted by the parathyroid gland and stimulates the tightly regulated renal enzyme 25-OH-D-I-α-hydroxylnse to make more 1, 25-(OI-I)2D from the' large circulating ,pool of 25-OH-D. The resulting increase in 1, 25-(OH)2D (with the rise in PTH) causes an increase in calcium transport within the intestine, bone and kidney. All these events raise plasma calcium levels back to normal, which in turn is sensed by the calcium receptor of the parathyroid gland. The further secretion of PTH is turned off not only by the feedback action of calcium, but also by a short feedback loop involving 1, 25-(OH)2D directly suppressing PTH synthesis in the parathyroid gland.
Complete history taking is an initial step in diagnosis. You will ask the patient about present complaints, past history, family history, any drug allergy and also the kind of diet
What is Nucleotides? Nucleotides are the basic building blocks of nucleic acids. Each nucleotide is composed of a nitrogen base, a 5-carbon sugar called a pentose, and an ass
Q. How Bone density affect osseointegration? The most important bone property is density which is influenced by factors such as patient age and genetics. Higher density bones h
Define Feeding and Nutritional Management for Neuro trauma? The main objective of nutritional management is to counteract the hypermetabolism associated with inflammation. The
Explain the effect on Minerals of the Human milk? There appears to be no relationship between dietary intake and concentrations in milk for copper, iron or zinc. Iron supplemen
Define precaution for estimation of vitamin c in lemon juice? 1. Rinse all glassware with 3% metaphosphoric acid before you begin your practical and subsequently each time you
Q. What is the bone matrix? What are its main components? Bone matrix is the content that fills the intercellular space of the osseous tissue the bone matrix is made of mineral
Many definitions of species have been offered, but none of them proved to be satisfactory. The definitions did not categorically provide the basis to decide whether two similar gro
What is the optimum percentage of forest area recommended by the national forest policy (1988) for the plains and the hills respectively? List any four problems caused because of d
Do algae reproduce sexually or asexually? There are algae that replicate sexually and there are algae that replicate asexually. In unicellular algae reproduction is usually
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +1-415-670-9521
Phone: +1-415-670-9521
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd