Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
A large number of integral proteins in eukaryotes do not traverse the membrane but are anchored in one or other leaflet of the bilayer through covalent attachment to a hydrocarbon chain. Several proteins, having the prion protein the causative agent of mad cow disease are stably anchored at the cell surface by covalent linkage of their C-terminal amino acid to the headgroup of a phosphatidylinositol lipid by an ethanolamine-phosphate-trimannose-glucosamine bridge, so-called GPI (glycosyl phosphatidylinositol)-anchored proteins. This difficult structure is built up by sequential addition of the individual sugar residues and ethanolamine phosphate to phosphatidylinositol. The C-terminal hydrophobic signal peptide is deleted from the protein in the lumen of the RER and the preformed GPI anchor added to the new exposed C- terminal amino acid.
figure: Lipid-modified proteins. (a) A glycosyl phosphatidylinositol-anchored protein (G, glucosamine; M, mannose; EtP, ethanolamine phosphate); (b) A myristoylated protein; (c) A prenylated protein; (d) a palmitoylated protein. Some proteins are also customized on Cys residues with covalently attached palmitate (C16:0) (palmitoylated proteins). These have some with membrane-spanning polypeptides (fig. 2d), some prenylated proteins and some myristoylated proteins. Various of the proteins having in cell signaling, like as the G proteins and the Ras family of proteins are lipid modified.
An increase in the calcium conductance of all sarcoplasmic reticulum membranes of a skeletal muscle with no external forces on it leads to A. an increase in the amount of calci
Lungs - Respiration Lungs can be simple, characterised by air exchange with surrounding environment by diffusion only. These are called the diffusion lungs and are present in
How is snow - blindness caused in humans? a) Mention the site where syngamy happens in amphibians and reptiles correspondingly.
Determine the prevention of Cholera Prevention: Following recommendations are there to prevent cholera outbreak: Drink only water that you have boiled or treated with
Chromosomes, coloured bodies, are composed of proteins and DNA; so are chromatids. At metaphase I there are 46 chromosomesaligned in pairs along the human cells equatorial plate. A
Explain about the term- Chroma Chroma is the relative purity or strength of the spectral colour and its numerical value extend from (/0) for neutral colours to (/8) for the stro
How is the concept of chromosome related to the concept of the gene? A chromosome is a DNA molecule and chromosome may contain several different genes and as well DNA portions
Define the term - lamellac The inner membrane is folded into very closely packed membranes called the lamellac. The lamellae flatten out at regular intervals into structures c
Leptospirosis Synonyms: Weil’ disease, canicola fever, 7-day fever Leptospirosis is an important and widespread zoonosis. It was first described by Adolf Weil in 1886 when h
State the term - Halsted Reitan varies with the particular test Scoring for the Halsted Reitan varies with the particular test, such that individual scores may be expressed in
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd