Define hexokinase, Biology

Assignment Help:

Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate.   Thus  when  PFK  is  inhibited and  fructose  6-phosphate builds  up and so does glucose  6-phosphate  due to these two metabolites  are in equilibrium  by phosphoglucoisomerase. Hexokinase inhibition then reinforces the inhibition at the PFK step. At first sight this seems commonly as it is usually the first irreversible step of a pathway (the committed step) that is the major control step. On this basis, it may appear in which hexokinase should be the main control enzyme not PFK.  Furthermore,   glucose 6-phosphate the product of the hexokinase reaction can also feed into glycogen synthesis or the pentose phosphate pathway. Thus the first irreversible step which is exclusive to glycolysis is which catalyzed by PFK and therefore this is the main control step.

 


Related Discussions:- Define hexokinase

Define heterochromatin, Heterochromatin: Compact, gene-poor areas of a gen...

Heterochromatin: Compact, gene-poor areas of a genome, which are enriched in the simple sequence repeats. As it may be impossible to clone, heterochromatin is generally ignored wh

Enzyme model, allosteric regulation project idea

allosteric regulation project idea

Marine biology, What are the four characteristics that all chordates have ...

What are the four characteristics that all chordates have at some stage of their lifecycle ?

Growth regulators, Growth Regulators Besides the major five hormones, ...

Growth Regulators Besides the major five hormones, polyamines can also exert regulatory control over growth and development at micromolar concentrations. They are widespread a

Are the phloem and the xylem made of living cells, Are the phloem and the x...

Are the phloem and the xylem made of living cells? The cells of phloem are living cells and the cells that constitute the xylem ducts are dead cells killed by the lignin deposi

Determine the neuropsychological assessment, Determine the Neuropsychologic...

Determine the Neuropsychological assessment  Neuropsychological assessment typically involves the functional areas of general intellectual capacities; memory; speed and accurac

Explain fluconazole, Fluconazole Fluconazole is active against most  Ca...

Fluconazole Fluconazole is active against most  Candida species other than C. krusei, which is intrinsically resistant, and many strains of C. glabrata, which are increasingly

Viral diseases, How do measles and HIV virus affects the bodies organisms

How do measles and HIV virus affects the bodies organisms

What are the factors that for influencing photosynthesis, What are the fact...

What are the factors that for influencing photosynthesis also interfere with the gross primary productivity? Mostly water and light, but also mineral salts, temperature and car

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd