Define hexokinase, Biology

Assignment Help:

Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate.   Thus  when  PFK  is  inhibited and  fructose  6-phosphate builds  up and so does glucose  6-phosphate  due to these two metabolites  are in equilibrium  by phosphoglucoisomerase. Hexokinase inhibition then reinforces the inhibition at the PFK step. At first sight this seems commonly as it is usually the first irreversible step of a pathway (the committed step) that is the major control step. On this basis, it may appear in which hexokinase should be the main control enzyme not PFK.  Furthermore,   glucose 6-phosphate the product of the hexokinase reaction can also feed into glycogen synthesis or the pentose phosphate pathway. Thus the first irreversible step which is exclusive to glycolysis is which catalyzed by PFK and therefore this is the main control step.

 


Related Discussions:- Define hexokinase

Citric acid cycle, Citric Acid Cycle The citric acid cycle, also known ...

Citric Acid Cycle The citric acid cycle, also known as tricarboxylic acid (TCA) cycle, lies at the heart of aerobic metabolism. it is involved in the breakdown of all three maj

Define the uremia and nitrogen disposal, Define the Uremia and Nitrogen Dis...

Define the Uremia and Nitrogen Disposal? In animals, faecal and renal nitrogen were enhanced and decreased uremia was seen in normal and nephrectomised animals. The mechanisms

Ribosomes in eukaryotic, Q. How dissimilar are the location of ribosomes in...

Q. How dissimilar are the location of ribosomes in eukaryotic and in prokaryotic cells? In eukaryotic cells they can also be found free in cytoplasm and mainly adhered to the e

Open or blunderbuss apex or divergent roots, Open or Blunderbuss Apex or di...

Open or Blunderbuss Apex or divergent roots The mechanical cleaning & shaping of teeth with blunderbuss canal apex are very difficult if not impossibly orthogratly due to 1

Risk factor modification, Risk Factor Modification :  Even after CABG,...

Risk Factor Modification :  Even after CABG, patients are at risk of progression of native coronary artery disease and development of lesions in the conduits. Modification of

Define factorial method to calculate nitrogen requirements, Define Factoria...

Define Factorial method to Calculate Nitrogen Requirements? The nitrogen requirements have been calculated by a factorial method suggested by different expert groups, described

Coronal disassembly-endodontics principles and practice, Coronal Disassembl...

Coronal Disassembly -If the existing restoration functionally designed well fitting and esthetically pleasing , -The access the pulp chamber during retreatment is better app

Describe about the tertiary prevention - food allergy, Describe about the T...

Describe about the Tertiary Prevention - food allergy? The tertiary allergy prevention, as you already know, focus on patients with symptoms. Hence, the strategies will target

ALGAE., HOW ARE THE ORIGIN AND EVOLUTION OF ALGAE..

HOW ARE THE ORIGIN AND EVOLUTION OF ALGAE..

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd