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Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate. Thus when PFK is inhibited and fructose 6-phosphate builds up and so does glucose 6-phosphate due to these two metabolites are in equilibrium by phosphoglucoisomerase. Hexokinase inhibition then reinforces the inhibition at the PFK step. At first sight this seems commonly as it is usually the first irreversible step of a pathway (the committed step) that is the major control step. On this basis, it may appear in which hexokinase should be the main control enzyme not PFK. Furthermore, glucose 6-phosphate the product of the hexokinase reaction can also feed into glycogen synthesis or the pentose phosphate pathway. Thus the first irreversible step which is exclusive to glycolysis is which catalyzed by PFK and therefore this is the main control step.
Q. Pathology of mitral regurgitation? During left ventricular systole as the pressure rises in left ventricle, blood is pumped simultaneously both into aorta and left atrium. T
Explain about the Ocular Haemodynamics. The pressure in the ocular arteries can be measured by optical ophthalmodynamometer. The intraocular pressure is raised to the level tha
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With the development of electron microscopy, it was possible to have an in depth knowledge of the interface between the implant and the tissues. Branemark was the pioneer in the fi
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