Define hexokinase, Biology

Assignment Help:

Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate.   Thus  when  PFK  is  inhibited and  fructose  6-phosphate builds  up and so does glucose  6-phosphate  due to these two metabolites  are in equilibrium  by phosphoglucoisomerase. Hexokinase inhibition then reinforces the inhibition at the PFK step. At first sight this seems commonly as it is usually the first irreversible step of a pathway (the committed step) that is the major control step. On this basis, it may appear in which hexokinase should be the main control enzyme not PFK.  Furthermore,   glucose 6-phosphate the product of the hexokinase reaction can also feed into glycogen synthesis or the pentose phosphate pathway. Thus the first irreversible step which is exclusive to glycolysis is which catalyzed by PFK and therefore this is the main control step.

 


Related Discussions:- Define hexokinase

Assume complete absorption, How many pints (473 ml) of Fat Tire amber ale c...

How many pints (473 ml) of Fat Tire amber ale can an 80 kg person drink in Arizona before reaching the blood alcohol limit? Fat Tire's ethanol concentration of 5.3% (v/v). Assume c

Molluscan kidney, Normal 0 false false false EN-IN X-...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Codon, Codon is the group of three consecutive nucleotides within the mess...

Codon is the group of three consecutive nucleotides within the messenger RNA (mRNA) which encodes a message to initiate translation, to incorporate the specific amino acid into th

Exterrral and internal environment, Exterrral and Internal Environment Le...

Exterrral and Internal Environment Let us try to understand the concept of environment with some examples. Can you identify the environment of a single carp fish in the pond? It

Which are the organs of the excretory system, Q. Which are the organs of th...

Q. Which are the organs of the excretory system? The excretory system is formed of ureters (two), kidneys (two), bladder and urethra.

Can diseases be etiological factor for diabetes, Q. Can Diseases be etiolog...

Q. Can Diseases be etiological factor for diabetes? Diseases: In aging, a very important cause of diabetes could be an underlying disease. Diabetes occurs secondary lo some ot

Bile acid sequestrants for coronary prevention, These are safe and free of ...

These are safe and free of systemic side effects. However, gastrointestinal side effects are common, and compliance is poor. The average LDL decreases by approximately 15 per cent

Limitations of computed tomograpy scan, Limitations of Computed Tomograpy S...

Limitations of Computed Tomograpy Scan  This technology is costly  Increased amount for radiation

Mechanism of carcinogenesis, Mechanism of Carcinogenesis In the preced...

Mechanism of Carcinogenesis In the preceding sub-section you learnt that carcinogenesis is a multistep process. Even though cancer may be caused by many agents chemical, p

What is meant by the arch reflex, What is meant by the arch reflex? In ...

What is meant by the arch reflex? In some situations the movement of the skeletal striated muscles does not depend upon commands of the superior motor neurons, i.e., it is not

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd