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Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate. Thus when PFK is inhibited and fructose 6-phosphate builds up and so does glucose 6-phosphate due to these two metabolites are in equilibrium by phosphoglucoisomerase. Hexokinase inhibition then reinforces the inhibition at the PFK step. At first sight this seems commonly as it is usually the first irreversible step of a pathway (the committed step) that is the major control step. On this basis, it may appear in which hexokinase should be the main control enzyme not PFK. Furthermore, glucose 6-phosphate the product of the hexokinase reaction can also feed into glycogen synthesis or the pentose phosphate pathway. Thus the first irreversible step which is exclusive to glycolysis is which catalyzed by PFK and therefore this is the main control step.
When a ventricQlar septa1 defect (VSD) is present, with no aortic stenosis, the peak velocitgr across the defect reflects the difference in pressure between the right ventricle an
Copulation and Fertilisation in Hermaphrodites Copulation between hermaphrodites is common. Flatworms possess a cirrus and penis that is inserted into the uterine vaginal ope
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Define the term -Aqueous Movement and Outflow There are two movements of the aqueous humour that occur-thermal flow and bulk flow. Thermal flow is, an internal circulation of
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Define Nutritional Management of Food Allergies and Food intolerance? In this unit we will be discussing the adverse reactions associated with food. You may have read or heard
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