Define hexokinase, Biology

Assignment Help:

Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate.   Thus  when  PFK  is  inhibited and  fructose  6-phosphate builds  up and so does glucose  6-phosphate  due to these two metabolites  are in equilibrium  by phosphoglucoisomerase. Hexokinase inhibition then reinforces the inhibition at the PFK step. At first sight this seems commonly as it is usually the first irreversible step of a pathway (the committed step) that is the major control step. On this basis, it may appear in which hexokinase should be the main control enzyme not PFK.  Furthermore,   glucose 6-phosphate the product of the hexokinase reaction can also feed into glycogen synthesis or the pentose phosphate pathway. Thus the first irreversible step which is exclusive to glycolysis is which catalyzed by PFK and therefore this is the main control step.

 


Related Discussions:- Define hexokinase

Tautomeric shifts, The original DNA sequence when ,transcribed and translat...

The original DNA sequence when ,transcribed and translated would yield five successive valine residues. But the altered sequence would correspondingly read one aspartate and four s

Fluids requirement during congestive cardiac failure, Q. Fluids requirement...

Q. Fluids requirement during congestive cardiac failure? Fluids: Fluid intake should be monitored in accordance with urine output and severity of oedema. Fluid restriction is

What are the factors that for influencing photosynthesis, Q. What are the f...

Q. What are the factors that for influencing photosynthesis also interfere with the gross primary productivity? Mostly light and water, but as well mineral salts, carbon dioxid

Explain brachial or radial approach, Q. Explain Brachial or Radial Approach...

Q. Explain Brachial or Radial Approach ? This technique involves performing the coronary angiogram through the right brachial artery in the right ante-cubital fossa. Usually a

Define prevention of iron deficiency, Define Prevention of Iron Deficiency?...

Define Prevention of Iron Deficiency? Iron deficiency anaemia accounts for approximately one-half or more of all the anaemia's seen worldwide. Iron deficiency without anaemia a

Reagents for determination of saponification number of fats, Define Reagent...

Define Reagents for Determination of the Saponification Number of Fats? 0.5 N alcoholic KOH 0.5 N HCI Solid sodium carbonate 1% alcoholic solution of methyl orange

What is cholesterol, Q. What is Cholesterol? In its free, unesterified ...

Q. What is Cholesterol? In its free, unesterified form cholesterol is a major component (together with phospolipid) of cell membranes. Its presence helps to stabilize membrane

Explain about the commercial sterilization, Explain about the Commercial St...

Explain about the Commercial Sterilization? Sterilization is the most extreme heat treatment given in preservation of food by heat. Usually target organism is a heat resistant

Human reproduction, Why is the human placenta referred to as haemochorial t...

Why is the human placenta referred to as haemochorial type? Name the hormone it secretes to facilitate parturition.

Spermiogenesis - spermatogenesis, Spermiogenesis - Spermatogenesis At ...

Spermiogenesis - Spermatogenesis At the end of the meiosis the spermatids appear as simple spherical cells with a centrally located nucleus. Their differentiation into sperm r

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd