Define hexokinase, Biology

Assignment Help:

Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate.   Thus  when  PFK  is  inhibited and  fructose  6-phosphate builds  up and so does glucose  6-phosphate  due to these two metabolites  are in equilibrium  by phosphoglucoisomerase. Hexokinase inhibition then reinforces the inhibition at the PFK step. At first sight this seems commonly as it is usually the first irreversible step of a pathway (the committed step) that is the major control step. On this basis, it may appear in which hexokinase should be the main control enzyme not PFK.  Furthermore,   glucose 6-phosphate the product of the hexokinase reaction can also feed into glycogen synthesis or the pentose phosphate pathway. Thus the first irreversible step which is exclusive to glycolysis is which catalyzed by PFK and therefore this is the main control step.

 


Related Discussions:- Define hexokinase

Explain how inhibition might contribute, We now understand that mutations t...

We now understand that mutations that cause the inhibition of apoptosis are found in tumors. Because proliferation itself is not induced by the inhibition of apoptosis, explain how

The cross between a tall pea plant and a short pea plant, In peas, tall pla...

In peas, tall plants are dominant to short plants. A cross between a tall pea plant and a short pea plant results in half the progeny being tall, and the other half being short. Th

Blood supply of the heart, The heart is supplied exclusively by the right a...

The heart is supplied exclusively by the right and left coronary arteries. The coronary arteries are functional end arteries. There is no effective anastamosis between right and le

Explain lock and key model, Fischer 's template or lock and key model ...

Fischer 's template or lock and key model According to this model, the catalytic site of the enzyme has a proper conformation compatible to a specific substrate even  in  the a

Vitamins requirement in dyslipidemia, Q. Vitamins requirement in dyslipidem...

Q. Vitamins requirement in dyslipidemia? Antioxidants and flavonoids, natural vitamin E, vitamins C and Aare nutrients (vitamins) that scavenge cell-damaging free radicals and

Contractile vacuole - protozoans, Contractile vacuole - Protozoans The...

Contractile vacuole - Protozoans The contractile vacuoles may differ in complexity in various groups of protozoans. In amoebae the vacuoles are carried around in the cytoplasm

Taxonomy, A In taxonomy, what is a "KEY" ? List the different types of key...

A In taxonomy, what is a "KEY" ? List the different types of keys. How are they prepared and what are they used for ?sk question #Minimum 100 words accepted#

Photosynthesis, test to prove that carbondioxide is needed for photosynthes...

test to prove that carbondioxide is needed for photosynthesis to take place

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd