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Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate. Thus when PFK is inhibited and fructose 6-phosphate builds up and so does glucose 6-phosphate due to these two metabolites are in equilibrium by phosphoglucoisomerase. Hexokinase inhibition then reinforces the inhibition at the PFK step. At first sight this seems commonly as it is usually the first irreversible step of a pathway (the committed step) that is the major control step. On this basis, it may appear in which hexokinase should be the main control enzyme not PFK. Furthermore, glucose 6-phosphate the product of the hexokinase reaction can also feed into glycogen synthesis or the pentose phosphate pathway. Thus the first irreversible step which is exclusive to glycolysis is which catalyzed by PFK and therefore this is the main control step.
Q. How to investigate aortic stenosis by Exercise Testing? Exercise testing is relatively contraindicated in patients with aortic stenosis. Its diagnostic accuracy to pick up a
Golgi complex is the organelles in animal cells having a sequence of þattened sacs which sort, chemically modify, and package proteins produced on the rough endoplasmic reticulum.
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Types of Mechanism - Stress Condition Plants have evolved a variety of mechanisms to withstand stress conditions. In many cases we can precisely define the way plants enable t
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Determine requirements of Vitamins at high altitude? It is observed that requirement of vitamins is not different as compared to plains. In humans, exposure to high altitude ha
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brief account on classification and general characters of protozoa
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