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Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate. Thus when PFK is inhibited and fructose 6-phosphate builds up and so does glucose 6-phosphate due to these two metabolites are in equilibrium by phosphoglucoisomerase. Hexokinase inhibition then reinforces the inhibition at the PFK step. At first sight this seems commonly as it is usually the first irreversible step of a pathway (the committed step) that is the major control step. On this basis, it may appear in which hexokinase should be the main control enzyme not PFK. Furthermore, glucose 6-phosphate the product of the hexokinase reaction can also feed into glycogen synthesis or the pentose phosphate pathway. Thus the first irreversible step which is exclusive to glycolysis is which catalyzed by PFK and therefore this is the main control step.
Legal level -Pollution control Pollution must be controlled by effective legislation also. Like USA, Japan, Germany and many other countries a comprehensive legislation for pr
Which of the following results from the elimination of DNA helicase activity in a cell? A. The melting of the DNA double helix at the site of replication initiation will fail t
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Define Nutrient Needs and Recommended Dietary Intake? Table depicts growth of normal well-to-do Indian children. Their intake is the criteria to assess nutrient requirements t
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