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Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate. Thus when PFK is inhibited and fructose 6-phosphate builds up and so does glucose 6-phosphate due to these two metabolites are in equilibrium by phosphoglucoisomerase. Hexokinase inhibition then reinforces the inhibition at the PFK step. At first sight this seems commonly as it is usually the first irreversible step of a pathway (the committed step) that is the major control step. On this basis, it may appear in which hexokinase should be the main control enzyme not PFK. Furthermore, glucose 6-phosphate the product of the hexokinase reaction can also feed into glycogen synthesis or the pentose phosphate pathway. Thus the first irreversible step which is exclusive to glycolysis is which catalyzed by PFK and therefore this is the main control step.
Amino Acids and Peptide Bonds, Protein Structure - The graduate can construct models of the structure and function of amino acids and peptide bonds, predict ionization of an amin
Temperature - Seed Dormancy Low temperature treatment is an essential prelude to germination in many seeds, and high temperature may be inhibitory at the time of germination.
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Anti-retroviral drugs are given to the patient. They lesser the viral load and gives relief from infection, but it is not lasting it is temporary relief i.e. it cannot cure.
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Enzymes and recombinant DNA technology Recombinant DNA technology, also called as genetic engineering makes use of a variety of enzymes, particularly restriction endonucleases
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