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Define Functions of selenium in humans?
Until recently, the only known metabolic role of selenium in humans was as a component of glutathione peroxidase which along with vitamin E and superoxide dismutase forms a part of the and-oxidant defense system. However, more selenoproteins are being discovered and currently it is estimated that 50-100 selenoproteins are present in animals. Selenoproteins in animals and humans are involved in protection from oxidative damage, maintaining adequate thyroid hormone status and protection from injury by a heavy metal like mercury. Three major enzyme systems in which selenium plays an important role have been identified in humans.
These include:
a) Glutathione peroxidases,
b) Iodothyronine deiodonases, and
C) Selenoproteins P and W
Match each of the methods or vectors below to an appropriate form of gene therapy, assigning two methods or vectors to each form. Use each method or vector only once. Methods/vec
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