Define functions of manganese, Biology

Assignment Help:

Define Functions of Manganese?

Like other micro minerals, Mn also functions in mammalian enzyme systems. It can function both as an integral part of metalloenzymes and as an enzyme activator. Manganese containing metalloenzymes are few, as shown in Table, whereas enzymes activated by Mn are much larger in number. Most of these metal activations by Mn are non-specific, as magnesium (Mg) can substitute for Mn. There are a few exceptions where Mn be specifically needed for activation. Examples include, activation of glycosyl transferases, phosphoenol/phruvate carboxykinase and glutarnine synthetase.

Glutamine synthetase found in high concentration in the brain catalyzes the following reaction:

NH3 + Glutamate + ATP + Glutamine + ADP + Pi

Thus, glutamate synthetase converts potentially toxic ammonia into glutamine and helps in the removal of ammonia (NH3) as it is generated. It is interesting to note that even in severe Mn deficiency in animals, brain glutamine synthetase activity is maintained normal, suggesting that this enzyme has a high priority among the enzymes activated by Mn or that Mg can replace Mn.


Related Discussions:- Define functions of manganese

Explain pericardial effusion, Q.Explain Pericardial Effusion? The confi...

Q.Explain Pericardial Effusion? The configuration of the heart in pericardial effusion depends on the volume of fluid and its distribution. It may have a globular or non-speci

Explain the sub-clinical protein energy malnutrition, Explain the Sub-clini...

Explain the Sub-clinical Protein Energy Malnutrition? You have already learnt that clinical forms of PEM represent only a small proportion of the total cases of PEM in a commun

Are the following statements true for eukaryotes, Are the following stateme...

Are the following statements true for eukaryotes , prokaryotes, both groups, or neither group? Answer They use a deoxyribonucleoside triphosphate as their energy currency"D They us

Explain kingdom protista, Kingdom Protista The protistans are a complex a...

Kingdom Protista The protistans are a complex and diverse group of organisms that are placed together simply because they are all single celled eukaryotes but some form rather sp

How much carbohydrates taken for management of obesity, How much Carbohydra...

How much Carbohydrates taken for management of obesity? Carbohydrates in the form of non-starch poly-saccharides provide bulk and satiety value to the reducing diet. They are a

What the enzymes do to reaction, What do enzymes do to a reaction? Indicate...

What do enzymes do to a reaction? Indicate all that are correct. a. Lower the activation energy b. Reverse the equilibrium c. Lower the equilibrium d. Increase the reac

Explain cholera, Cholera  The risk of infection with cholera is very lo...

Cholera  The risk of infection with cholera is very low in tourists. The parenteral vaccine licensed in the US is no longer available. One oral vaccine called Dukoral is availa

Hardy - weinberg law, HARD Y - WEINBERG LAW - Proposed by G.H. Hard...

HARD Y - WEINBERG LAW - Proposed by G.H. Hardy and W. Weinberg in 1908 independently. The law states "the frequency of genes or alleles in a population remains constant

Explain about gamma diversity, Q. Explain about gamma diversity? Gamma ...

Q. Explain about gamma diversity? Gamma (g) richness refers to the rate of change across larger landscape gradients and gamma diversity is a measure of the overall diversity fo

VASCULAR PLANTS., WHAT TRAITS ALLOWED VASCULAR PLANTS TO GROW TALL

WHAT TRAITS ALLOWED VASCULAR PLANTS TO GROW TALL

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd