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Define Function of thiamin as Regulator of enzyme activity?
Thiamin regulates the enzymes involved in carbohydrate metabolism. These are:
a) Pyruvate dehydrogenase, which provides a key link between glycolytic pathway and citric acid cycle.
b) α-ketoglutarate dehydrogenase in citric acid cycle and transketolase involved in pentose phosphate pathway.
c) Each enzyme contains a decarboxylase moiety that binds TPB at the active site, a lipoic acid binding moiety, a flavoprotein and one or more regulatory components that toggle the enzyme complex between the active form and the inactive form.
d) A fourth thiamin requiring enzyme is a branched-chain ketoacid dehydrogerzase, which plays a role in the metabolism of branched-chain amino acids.
Access through the crown Advantages : -Allow for better isolation with the rubber dam -Better esthetic anf functioning. -Good coronal seal between visits Limitations : -Proc
what is the effect of insuline in body ?
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