Define fluconazole, Biology

Assignment Help:

Define Fluconazole

It is a weaker inhibitor of CYP3A4 than itraconazole or ketoconazole but may still increase serum concentrations of drugs metabolized by 3A4, like cyclosporine, simvastatin  (Zocor) and lovastatin (Mevacor, and others). Fluconazole is a strong inhibitor of CYP2C9 and can therefore enhance serum concentrations of tacrolimus, phenytoin (Dilantin, and others), zidovudine (Retrovir), warfarin (Coumadin, and others) and other drugs metabolized by 2C9. Concomitant administration of rifampin (Rifadin, and others) can lower serum concentrations of fluconazole.

 


Related Discussions:- Define fluconazole

Determine the bone density, Bone Density The compact bone surrounding d...

Bone Density The compact bone surrounding dense evenly spaced trabeculae with small cancellous spaces is ideal/suitable for implant placement. Dense or porous cortical bone is

Explain about the term demand, Explain about the term demand. Demand:...

Explain about the term demand. Demand: Potential customers (consumers, buyers or households) of a good or a service into a market, which normally a demand curve is utiliz

Dose-response extrapolation, Dose-response extrapolation In order to be...

Dose-response extrapolation In order to be compared to human exposure levels, the animal data need to be extrapolated to doses much lower than those studied. This extrapolation

Blood, How the blood is circulated with the help of Heart?

How the blood is circulated with the help of Heart?

Define about the types of indicators, Define about the Types of indicators?...

Define about the Types of indicators? The various types of indicators used are: (i) Acid-base indicators (ii) Redox indicators (iii) Metal ion indicators (iv) Preci

Explain cake mix evaluation - performance evaluation, Cake mix evaluation  ...

Cake mix evaluation  Originally, cake mix formulations were very similar to bakery cakes and utilized standard "Hi-Ratio" cake oils; however, development of improved cake mixes

Vitamins and minerals requirement in diabetes, Q. Vitamins and minerals req...

Q. Vitamins and minerals requirement in diabetes? The recommendation of vitamins and minerals is the same as for general population. However, lower levels of magnesium are ass

Define measuring body composition - underwater weighing, Define Techniques ...

Define Techniques for Measuring Body Composition - Underwater weighing? Underwater weighing (densitometry): It applies the Archimedean principle of water displacement by the fu

Terrestrial and aquatic ecosystem, Terrestrial and Aquatic Ecosystem W...

Terrestrial and Aquatic Ecosystem What is common between a terrestrial and an aquatic ecosystem. Both have similar type of trophic structure. They possess an autotrophic layer

Haemodynamics of tricuspid regurgitation, Q. Haemodynamics of Tricuspid reg...

Q. Haemodynamics of Tricuspid regurgitation? Right Atrial pressure tracing shows a prominent ‘v' wave and these cannot be appreciated in a patient with atrial fibrillation. RV

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd