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Erythropoietin (EPO)
A. acts by increasing the production of red blood cells by cells in the bone marrow.
B. is secreted by peritubular interstitial cells of the kidney cortex.
C. levels in the blood plasma serve as an actuating signal in a long-term negative feedback loop that controls the amount of oxygen in the peritubular interstitial spaces of the kidney cortex.
There are several anaplerotic reactions required to replenish intermediates of the TCA cycle. All of the following compounds can be used for these anaplerotic reaction except: -
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