Define erythroblastosis fetalis, Science

Assignment Help:

Define Erythroblastosis Fetalis

Besides the risk of a mismatch reaction during a second or during any subsequent  blood transfusion, giving Rh-positive, blood involves  risk in case of young Rh-negative girls.

This  is because of the  possibility of complication during  pregnancy if the  girl happens  to have  a Rh-positive foetus  in  her uterus any time later  in  life. The chances of any abnormalities resulting from Rh incompatibility are negligible during first pregnancy, 3% during second and 10% during third. This is due to following reasons:

1)  Red cells of the foetus are unable to cross normal placenta. There has to be some abnormality  in the placenta  before foetal red cells can enter the maternal circulation.

2)  Foetal red cells may be destroyed by maternal plasma before they can induce an antibody response. E.g., if mother is 0,  Rh negative  and the foetus  is A, Rh positive, the foetal red cells would be haemolysed by  the anti-A antibodies present in the maternal plasma.

3)  If the foetus and mother happen to be of same group, i.e., A,B or AB but mother is Rh -ve  and foetus Rh +ve,  during 2nd  and subsequent  pregnancies, mother gets sensitize with Rh antigents of  fetal blood,  resulting  in production  of anti-Rh  antibodies, which will destroy  foetal RBC, causing 'erythoblastosis foetalis'.

Although erythroblastosis foetalis may be  treated by exchange transfusion, the prevention is  routinely attempted  by desensitizing the mother for production of Rh antibodies during pregnancy. The desensitized mothers don't respond  to  foetal Rh+ve RBCs. Thus erythroblastosis foetalis is prevented.

Apart from the Rh incompatibility as a complication leading to loss of blood, there is another condition wherein the RBCs are deficient. This is referred to as anaemia, a disorder related to deficiency of erythrocytes. As a student of dietetics, you must be familiar with anaemia and its consequences.


Related Discussions:- Define erythroblastosis fetalis

Material Science, #1.During take-off, the wing of the airplane is actually ...

#1.During take-off, the wing of the airplane is actually subjected to a cyclic stress range of 150 MPa at a stress ratio of 0.1. Estimate the mean stress intensity factor, and the

Respiration, Respiration:  Food +  oxygen ->  carbon dioxide + water + ...

Respiration:  Food +  oxygen ->  carbon dioxide + water +  energy  Food is not only a source of energy, but also the nutrients used to build up the organisms' bodies. So we

What are the constituents of the intestinal juice, What Are the Constituent...

What Are the Constituents of the Intestinal Juice? Intestinal juice is also called succus entericus. The word succus means juice and entericus means intestinal. The digestive j

Explain maximum tubular secretory capacity - urine formation, Explain Maxim...

Explain Maximum Tubular Secretory Capacity The maximum rate at which tubules can transport a substance from the blood vessel to the lumen or from the lumen to the blood vessel

Psychology, how a student nurse can apply the knowledge of mental health an...

how a student nurse can apply the knowledge of mental health and mental hygiene in her personal and professional life

Define glucose and fructose - abnormal constituents of urine, Define Glucos...

Define Glucose and Fructose - Abnormal Constituents of Urine Abnormal Constituents of Urine The detection of abnormal constituents in urine indicates the presence of certa

Solid object.., what are the different kinds of solid object?

what are the different kinds of solid object?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd