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Define Effect of feeding method on drug availability?
The form in which a drug is administered or enters the body can influence its absorption, metabolism or excretion. This becomes more pronounced among critically ill patients who cannot consume drugs orally and are on enteral food support. If the drug has to be administered though the enteral feeding tube it needs to be either crushed or dissolved in a solvent. Crushing oral preparations to pass down the tube may alter their absorption time/activity.
Some of the drugs cannot be added to the food infusion as it may alter their stability. Several drugs are available only in the form of tablets or capsules, dissolving these in feed, water, alcohol or sorbitol may not always be feasible. Drug such as cimetidine, aluminium hydroxide, metaclorpromide are physically incompatible with enteral foods. Certain drugs like phenytoin form complexes with calcium and protein thereby resulting in markedly reduced absorption of this medication. Such drugs need to given only by stopping enteral feed infusions for 1-2 hours. Patients on total parenteral nutrition generally have a separate tube (catheter) for infusion of drugs. Toxicity/over dosage of drugs is frequently observed in case of certain drugs administered directly into the blood.
what are some examples of eperimenting palants?
Nervous System and Sense Organs The non-chordates also perform a variety of activities such as feeding, digestion, locomotion etc. For this aim, they have corresponding organs
Determine the term - Akinetic and Myoclonic Seizures Akinetic seizures are ordinarily seen only in children. Usually, an affected child collapses suddenly and without warning.
Osteogenesis The term osteogenesis describes essentially two distinctly different phenomena by which bone can become juxtaposed to an implant surface.
A 70-year old woman presents with a 1-hour history of crushing substernal chest pain. Shortly after admission, the patient expires. An autopsy reveals calcium deposits in the intim
Describe Stanley miller experiment to test the idea of probiotic synthesis. What is the primordial soup?
How bone implant interface can be evaluated 1) Evaluation of the bone - implant interface can be done by following: i) Implant mobility and discomfort a) Clinical implan
Q. Physical Signs of aortic regurgitation? Chronic severe aortic regurgitation is characterized by wide pulse pressure and multiple peripheral signs it produces. Sharp rapid up
Define absorption, transport and excretion of magnesium? Magnesium absorption to some extent is similar to that of Ca. Absorption of Mg occurs throughout the small intestine, a
how nerve signals are transmitted
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