Define chagas and arrhythmogenic right vent cardiomyopathy, Biology

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Chagas' Cardiomyopathy

It is common in south and Central America and is caused by Trypanosoma cruzi.

Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

It is marked by myocardial cell loss with partial or total replacement of RV muscle by adipose and fibrous tissue. The clinical manifestations are seen in adolescence or early adulthood, predominantly in males. Physical examination is normal. ECG shows inverted T in right precordial leads. They develop reentrant ventricular tachyarrhythmias of RV origin. LBBB configuration, usually precipitated by exercise. Sudden death is common. Management includes β-blockers, sotalol and amiodarone. Radiofrequency ablation, ICD and cardiac transplant are other options.


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