Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Define Biosynthesis and Secretion of Thyroid Hormones?
Histologically, the functional cells of the thyroid gland are arranged in follicles, which surround a central lumen containing a colloid in which the hormones are stored in the form of thyroglobulin. Thyroglobulin is a glycoprotein and is synthesized in the follicular cell as prothyroglobulin and the tyrosine units are iodinated in the intact protein. As you may have noticed in Figure, the iodide actively transported into the cells from extracellular fluid (ECF) is released from the thyroid cells into the colloid follicle where it is oxidized by thyroperoxiduse in the presence of hydrogen peroxide.
The oxidized iodine is then combined with the amino acid tyrosine in thyroglobulin to form mono and di-iodotyrosines (MITIDIT), which are again catalyzed by thyroperoxidase. These are then coupled to form triiodo to thyronine and tetraiodo- thyroxine. The iodinated thyroglobulin is absorbed back into the cells by a process known as pinocytosis. The iodinated thyroglobulin is hydrolyzed within the cells by the cellular proteolytic enzymes to release T4 and T3 into the blood circulation. Unutilized mono- and di-iodotyrosines are not released into the blood but axe conserved within the gland for further incorporation into thyroglobulin. In blood, these hormones bind to transport proteins mainly thyroxine-binding-protein and are distributed to the target cells in the peripheral tissues. All phases of biosynthesis and secretion of thyroid hormones are stimulated by thyroid-secretary hormone (TSH), which is secreted by anterior pituitary gland in response to low levels of thyroid hormones.
What is the function of the collagen fibers of the connective tissue? There are dissimilar collagen types. The major function of these proteins is to keep the shape and the str
All the cells present in the body contain genes and an approach targeted to modulate the expression of genes is known as gene therapy. This novel approach has emerged by the end of
Mr. Jones I.V. was hung at noon. It is a liter bag and is infusing at 65 ml/hr. How many hours will this bag last?
What is Cyanotic Spells ? Hypercyanotic or Cyanotic spell is a pediatric emergency, which requires prompt recognition, and intervention to prevent disabling cerebro-vascular i
Define Energy Requirement for Cancer Patients? It must be clear to you that cancer imposes increased energy demands because of the hyper-metabolic state of the disease process
Q What are the three periods into which interphase are divided? Interphase is the preceding phase to the mitotic division. It is divided into three periods, G1, S and G2 the le
Q. Are hookworms monoxenous or heteroxenous? The Monoxenous are Hookworms that is their life cycle depends only on one host.
Use the genetic code table Assignment34 The codon GCA specifies which amino acid?
Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4
DISORDER S OF THE ADRENAL CORTEX - ( i ) ADDISON'S DISEASE : This disease is caused by the deficiency of mineralocorticoids and glucocorticoids. Its symptoms include l
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +1-415-670-9521
Phone: +1-415-670-9521
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd