Define Binding of Protein with Other Compounds?

In addition to water, lipids and volatile flavours, food proteins can bind a number of other substances through weak interactions or through covalent bonds, depending upon their chemical structure. E.g. pigments, synthetic dyes (which may be used for analytical determination of proteins) and substances with mutagenic, sensitizing biological activity. Such binding may result both in enhanced toxicity or detoxification and in some cases; the nutritional values can be adversely affected.