Define aortic regurgitation, Biology

Assignment Help:

Q. Define Aortic regurgitation?

Aortic regurgitation is a common valvular disease that may present chronically or acutely. Normally the integrity of valve closure depends upon the anatomy of valve leaflets and on three dimensional geometry of aortic root and sinuses of Valsalva. Wide variety of causes may lead to aortic regurgitation. Usually 50 per cent of valve replacements are due to diseases of valve and 50 per cent due to root disease. However, in India predominant cause of aortic valve replacement is still rheumatic.

Table : Causes of Aortic Regurgitation

                                                                  Acute                                             - Aortic dissection
                                                                                                                       - Trauma
                                                                                                                       - Leaflet perforation due to endocarditis
Chronic

                                                                 Valve leaflet disease                         - Congenital
                                                                                                                              Bicuspid
                                                                                                                              Unicuspid
                                                                                                                              Quadricuspid
                                                                                                                              Fenestrations
                                                                                                                         - Rheumatic
                                                                                                                         - Infective endocarditis
                                                                                                                         - Myxomatous degeneration
                                                                                                                         - Fibro calcific degeneration
                                                                                                                         - Systemic Lupus Erythematosus

                                                                                                                          - Rheumatoid
                                                                                                                          - Pharmacological agents

                                                                Aortic Root Disease                          - Hypertension
                                                                                                                          - Idiopathic root dilatation
                                                                                                                          - Marfan's Syndrome
                                                                                                                          - Aortic dissection
                                                                                                                          - Annuloaortic ecstasia
                                                                                                                          - Cystic medial necrosis
                                                                                                                          - Syphilis
                                                                                                                          - Ankylosing spondylosis
                                                                                                                          - Takayasu arteritis
                                                                                                                          - Psoriatic arthritis
                                                                                                                          - Reiter's Syndrome
                                                                                                                          - Relapsing Polychondritis
                                                                                                                          - Kawasaki disease
                                                                                                                          - Osteogeneses imperfecta
                                                                                                                          - Giant cell Arteritis
                                                                                                                          - Ehlers - Danlos Syndrome

Sub Valvular                                                                                                      - Discrete sub aortic stenosis

                                                                                                                          - VSD with aortic regurgitation due to prolapse

Majority of elderly hypertensive patients have trivial to mild aortic regurgitation due to varying degrees of root dilatation due to hypertension and degenerative changes in the valve. However, they are rarely of clinical importance and may not progress to severe aortic regurgitation.


Related Discussions:- Define aortic regurgitation

Glucagon and glucocorticoids, Important  aspects  related to regulation inc...

Important  aspects  related to regulation include: 1)  The hormones glucagon and glucocorticoids  which are  secreted  during  starvation stimulate  glucose-6-phosphatase to en

Pathophysiology, Case scenario Mr Kit Lee, a 28-year-old unrestrained dr...

Case scenario Mr Kit Lee, a 28-year-old unrestrained driver of a utility, was travelling on a highway at 100kph and swerved to miss road debris. He lost control and struck a tre

Neo-lamarckism, NEO-LAMARCKISM Modem modified form of Lamarck theory...

NEO-LAMARCKISM Modem modified form of Lamarck theory is regarded as Neo-Lamarckism. Mc Dougall (1938) found that time taken for training the mice was reducing gradually

Major objectives of diarrhoea, Q. Major objectives of diarrhoea? The ma...

Q. Major objectives of diarrhoea? The major objectives in the management of diarrhoea include: 1. Fluid and electrolyte replacement 2. Removal of cause (especially if inf

What is the endocrine function of the placenta, What is the endocrine funct...

What is the endocrine function of the placenta? The placenta is not a permanent gland of the endocrine system but it also has endocrinal function. The placenta produces estroge

Why is carbon monoxide toxic for humans, Q. Why is carbon monoxide toxic fo...

Q. Why is carbon monoxide toxic for humans? Hemoglobin "likes" carbon monoxide (CO) much more than it likes oxygen. When there is carbon monoxide in the inhaled air it binds to

What are the habits effect on implant, Habits: Any abnormal habits need...

Habits: Any abnormal habits needs to be identified. Following habits may have detrimental effect on the implant: 1. Parafunction -  Bruxism/ Clenching 2. Tongue Thrusting

What is tuberculosis, What is tuberculosis? How is the disease transmitted?...

What is tuberculosis? How is the disease transmitted? Is there treatment for tuberculosis? Tuberculosis is a disease caused by the Mycobacterium tuberculosis, bacteria which at

Determine the postovulatory phase of x menstrual cycle, Healthy human femal...

Healthy human female X is 25 years old and not pregnant.  During the postovulatory phase of X's menstrual cycle,   A.  there are high blood plasma levels of LH and FSH.

Genotype for each individual, The allele that causes albinism (p) is recess...

The allele that causes albinism (p) is recessive to the allele for normal pigmentation (P). A normal woman whose father is an albino marries an albino man whose parents are both no

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd