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Define and compare bone modeling and remodeling
Bone modeling is a surface-specific activity (apposition or resorption) that produces a net change in the sie and/or shape of a bone after initial bone formation in the embryonic or initial healing stage. It is an uncoupled process , that is bone structure alterations occur by independent action of osteoblasts and osteoclasts.
Bone remodeling differs from the other means of bone structure alteration in that osteoblasts and osteoclasts do not act independently but are coupled and bone resorption and formation occur at the same spot on a bone surface. It\ represents a change that occurs within mineralised bone without concomitant alteration of architecture of the tissue.
What is genes Duplication ? Duplication of genes can happen when a portion of a chromosome breaks off and attaches itself to the end of its homologous chromosome, as seen below
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