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Adverse Effects
The most common adverse effects of itraconazole are dose-related nausea and abdominal discomfort. Rash and serious hepatic toxicity can happen. The drug can cause hypokalemia, edema and hyper-tension. Congestive heart failure has been reported with itraconazole and the drug should not be used in patients with ventricular dysfunction.
Thrombocytopenia and leukopenia have also been reported. The intra-venous formulation have cyclodextrin, which can accumulate in azotemic patients; its use is not recommended in patients with creatinine clearance <30 mL/min.
Which gas in each of the following pairs would you expect to be more soluble in water? Why? (a) Oxygen and Carbon Dioxide (b) Nitrogen and Ammonia (c) Methane and Hydrogen Sulfide.
A cell in G1 of interphase has 12 chromosomes. How many chromosomes and DNA molecules will be found per cell when this original cell progresses to the G2?
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