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Models for the analysis of the survival times, or the time to event, data in which it is expected that a fraction of the subjects will not experience the event of interest. In a clinical setting, this often corresponds to the assumption that a fraction of patients treated for a disease will be cured whereas the rest will experience a recurrence. Commonly such models involve the fitting of finite mixture distributions.
Intervention analysis in time series : The extension of the autoregressive integrated moving average models applied to time series permitting for the study of the magnitude and str
The approach to statistics based on a frequency view of probability in which it is supposed that it is possible to consider an in?nite sequence of the independent repetitions of th
Treatment allocation ratio is the ratio of the number of subjects allocated to the two treatments in a clinical trial. The equal allocation is most usual in practice, but it might
#explanation of methods of collection of data..
Protocol is the formal document outlining the proposed process for carrying out the clinical trial. The basic features of the document are to study the objectives, patient selecti
Principal components analysis is a process for analysing multivariate data which transforms original variables into the new ones which are uncorrelated and account for decreasing
A family of the probability distributions of the form given as here θ is the parameter and a, b, c, d are the known functions. It includes the gamma distribution, normal dis
Behrens Fisher problem : The difficulty of testing for the equality of the means of the two normal distributions which do not have the equal variance. Various test statistics have
The method or technique for displaying the relationships between categorical variables in a type of the scatter plot diagram. For two this type of variables displayed in the form o
The method or technique for producing the sequence of parameter estimates that, under the mild regularity conditions, converges to maximum likelihood estimator. Of particular signi
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