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The type of longitudinal study in which the subjects receive different treatments on the various occasions. Random allocation is required to determine the order in which the treatments are received. The simplest such design includes two groups of the subjects, one of which receives each of the two treatments, A and B, in the order AB, while the other takes them in the reverse order. This is called as a two-by-two crossover design. While the treatment comparison is 'within-subject' rather than the 'between-subject', it is likely to need fewer subjects to achieve the given power. The study of such designs is not necessarily straight- forward because of the possibility of the carryover effects, that is left over effects of the treatment received on the first occasion which remain present into the second occasion. An attempt to minimize this problem is many times made by including the wash-out period between the two treatment occasions. Some of the authorities have suggested that this type of design should only be used if such carryover effects can be ruled out a priori. Crossover designs are only applicable to the chronic conditions for which short-term relief of the symptoms is the goal rather than a cure of it.
Genstat: The basic purpose piece of statistical software for the management and the analysis of data. The package incorporates the wide variety of data handling events and a wi
A metal fabrication process uses a die-cast metal fastener at a uniform rate of 300 units per year. Currently, this item is currently purchased from an external supplier at a unit
Data which occur when failure period is recorded which are dependent. Such type of data can arise in number contexts, for instance, in epidemiological cohort studies in which th
Battery reduction : A common term for reducing the number of variables of the interest in a study for the purposes of study and perhaps later data collection. For instance, an over
Invariant transformations to combine marginal probability functions to form multivariate distributions motivated by the need to enlarge the class of multivariate distributions beyo
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Grade of membership model: This is the general distribution free method for the clustering of the multivariate data in which only categorical variables are included. The model ass
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Resentful demoralization is the possible phenomenon in the clinical trials and intervention studies in which comparison groups not attaining a perceived desirable treatment become
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