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The type of longitudinal study in which the subjects receive different treatments on the various occasions. Random allocation is required to determine the order in which the treatments are received. The simplest such design includes two groups of the subjects, one of which receives each of the two treatments, A and B, in the order AB, while the other takes them in the reverse order. This is called as a two-by-two crossover design. While the treatment comparison is 'within-subject' rather than the 'between-subject', it is likely to need fewer subjects to achieve the given power. The study of such designs is not necessarily straight- forward because of the possibility of the carryover effects, that is left over effects of the treatment received on the first occasion which remain present into the second occasion. An attempt to minimize this problem is many times made by including the wash-out period between the two treatment occasions. Some of the authorities have suggested that this type of design should only be used if such carryover effects can be ruled out a priori. Crossover designs are only applicable to the chronic conditions for which short-term relief of the symptoms is the goal rather than a cure of it.
The contingency tables in which the row and column both the categories follow a natural order. An instance for this might be, drug toxicity ranging from mild to severe, against the
The diagnostic tools or devices used to approach the closeness to the linearity of the non-linear model. They calculate the deviation of so-called expectation surface from the plan
Lancaster models : The means of representing the joint distribution of the set of variables in terms of the marginal distributions, supposing all the interactions higher than a par
Geographical analysis machine is the procedure designed to detect the clusters of rare diseases in a particular area. Circles of fixed radii are created at each point of the squar
VIF is the abbreviation of variance inflation factor which is a measure of the amount of multicollinearity that exists in a set of multiple regression variables. *The VIF value
Per-experiment error rate is the possibility of the incorrectly rejecting at least one null hypothesis or assumption in the experiment including one or more tests or comparisons,
The Expectation/Conditional Maximization Either algorithm which is the generalization of ECM algorithm attained by replacing some of the CM-steps of ECM which maximize the constrai
Randomized consent design is the design at first introduced to overcome some of the perceived ethical problems facing clinicians entering patients in the clinical trials including
A term commonly encountered in the application of the agglomerative hierarchical clustering techniques, where it refers to the 'tree-like' diagram illustrating the series of steps
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