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The type of longitudinal study in which the subjects receive different treatments on the various occasions. Random allocation is required to determine the order in which the treatments are received. The simplest such design includes two groups of the subjects, one of which receives each of the two treatments, A and B, in the order AB, while the other takes them in the reverse order. This is called as a two-by-two crossover design. While the treatment comparison is 'within-subject' rather than the 'between-subject', it is likely to need fewer subjects to achieve the given power. The study of such designs is not necessarily straight- forward because of the possibility of the carryover effects, that is left over effects of the treatment received on the first occasion which remain present into the second occasion. An attempt to minimize this problem is many times made by including the wash-out period between the two treatment occasions. Some of the authorities have suggested that this type of design should only be used if such carryover effects can be ruled out a priori. Crossover designs are only applicable to the chronic conditions for which short-term relief of the symptoms is the goal rather than a cure of it.
The plot of the number of cases of the disease against the time period. A large and sudden increase corresponds to an epidemic. The example of this is shown in the figure drawn bel
A test for equality of the variances of the two populations having normal distributions, based on the ratio of the variances of the sample of observations taken from each. Most fre
The graphic representation of the alternatives in a decision making problem which summarizes all the possibilities foreseen by the decision maker. For instance, suppose we are give
Nested design is the design in which levels of one or more factors are subsampled within one or more other factors such that, for instance, each level of a factor B happens at onl
how to find the PDF and CDF of a gamma random variable with given equation?
Compliance : The extent to which the participants in a clinical trial follow trial protocol, for instance, following both the intervention regimen and trial procedures (clinical vi
#ques12. There is some evidence that REM sleep, associated with dreaming, may also play a role in learning and memory processing. For example, Smith and Lapp (1991) found increased
Lorenz curve : Essentially the graphical representation of cumulative distribution of the variable, most often used for the income. If the risks of disease are not monotonically in
hello I have a dataset including both categorical & numerical variable for market segmentation.how can i cluster them via k-means in matlab? thank you
A construction for events that happen in some planar area a, consisting of the series of 'territories' each of which comprises of that part of a closer to the particular event xi t
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