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The type of longitudinal study in which the subjects receive different treatments on the various occasions. Random allocation is required to determine the order in which the treatments are received. The simplest such design includes two groups of the subjects, one of which receives each of the two treatments, A and B, in the order AB, while the other takes them in the reverse order. This is called as a two-by-two crossover design. While the treatment comparison is 'within-subject' rather than the 'between-subject', it is likely to need fewer subjects to achieve the given power. The study of such designs is not necessarily straight- forward because of the possibility of the carryover effects, that is left over effects of the treatment received on the first occasion which remain present into the second occasion. An attempt to minimize this problem is many times made by including the wash-out period between the two treatment occasions. Some of the authorities have suggested that this type of design should only be used if such carryover effects can be ruled out a priori. Crossover designs are only applicable to the chronic conditions for which short-term relief of the symptoms is the goal rather than a cure of it.
How large would the sample need to be if we are to pick a 95% confidence level sample: (i) From a population of 70; (ii) From a population of 450; (iii) From a population of 1000;
Bioinformatics : Essentially the application of the information theory to biology to deal with the deluge of the information resulting from the advances in molecular biology. The m
Likert scales is often used in the studies of attitudes in which the raw scores are based on the graded alternative responses to each of a series of queries. For instance, the sub
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Modern hotels and certain establishments make use of an electronic door lock system. To open a door an electronic card is inserted into a slot. A green light indicates that the doo
This term sometimes used to describe the extra factor in variance of the sample mean when n sample values are drawn without the replacement from the finite population of size N. Th
Median is the value in a set of the ranked observations which divides the data into two parts of equal size. When there are an odd number of observations the median is middle v
The model for data containing continuous and categorical variables both.The categorical data are summarized by the contingency table and their marginal distribution, 182by the mult
Personal probabilities : A radically special approach for allocating probabilities to events than, for instance, the commonly used long-term relative frequency approach. In this ty
A family of the probability distributions of the form given as here θ is the parameter and a, b, c, d are the known functions. It includes the gamma distribution, normal dis
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