Coronary flow limiting stenoses, Biology

Assignment Help:

Coronary Vasoconstriction

1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor changes. Fixed flow limiting stenoses present smooth muscle cell atrophy and/or plaque rigidity and are associated with the predictable ischaemic threshold and a stable pattern of effort related myocardial ischaemia.

Dynamic stenoses are usually eccentric, with compliant segments of the wall and preserved muscular media, and are associated with a variable ishaemic threshold.

2) Vasoconstriction at the site of stenoses may result from (1) neural vasoconstrictor stimuli, (2) impairment of vasodilator mechanisms, (3) increased response of dysfunctional vascular smooth muscle cells to vasoconstrictor stimuli, or (4) variable combination of these mechanisms.

3) In animal models, and possibly in unstable patients, the severity of stenosis may also be modulated by platelet aggregates.


Related Discussions:- Coronary flow limiting stenoses

Biology Project, what does the future look like with trash in the ocean?

what does the future look like with trash in the ocean?

Clinical evaluation in the continuing care cycle, Clinical Evaluation in ma...

Clinical Evaluation in maintenance in the Continuing Care Cycle Examination of gingival contours, along with mechanical evaluation of the prosthesis, implants, and implant comp

Explain about the blanching - food processing, Explain about the Blanching ...

Explain about the Blanching - Food Processing? Blanching is used for variety of purposes. It is defined as a mild heat treatment applied to tissue (usually plant) prior to free

Chemical composition of chromatin, CHEMICA L COMPOSITION OF CHROMATIN ...

CHEMICA L COMPOSITION OF CHROMATIN Chromatin threads composed of DNA (31 %), RNA (2-5%) and proteins (Histon-36%, Non histon 28%). Histone and protamines are basic prote

How are human voices created, How are human voices created? Human voice...

How are human voices created? Human voice is formed with the help of muscles in the neck and the vocal cords. The tighter the vocal cords the higher the pitch of voice. This is

Succession, Similarities between autotrophic succession and heterotrophic s...

Similarities between autotrophic succession and heterotrophic succession

Define energy requirement for cancer patients, Define Energy Requirement fo...

Define Energy Requirement for Cancer Patients? It must be clear to you that cancer imposes increased energy demands because of the hyper-metabolic state of the disease process

What is the dosage and cost of micafungin, Dosage and cost of micafungin ...

Dosage and cost of micafungin The recommended dosage of micafungin is 50 mg/day for prophylaxis and 150 mg/day for treatment, both given IV as a single dose over 1 hour.

Do we know what causes mental illnesses or how to treat them, Do we know wh...

Do we know what causes mental illnesses, or how best to treat them? Mental illnesses take various forms: debilitating sadness in depression; uncontrollable repetitive actions i

Photosynthesis, explain the role of photophosphorylation and chemiosmosis i...

explain the role of photophosphorylation and chemiosmosis in photosynthesis

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd