Coronary flow limiting stenoses, Biology

Assignment Help:

Coronary Vasoconstriction

1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor changes. Fixed flow limiting stenoses present smooth muscle cell atrophy and/or plaque rigidity and are associated with the predictable ischaemic threshold and a stable pattern of effort related myocardial ischaemia.

Dynamic stenoses are usually eccentric, with compliant segments of the wall and preserved muscular media, and are associated with a variable ishaemic threshold.

2) Vasoconstriction at the site of stenoses may result from (1) neural vasoconstrictor stimuli, (2) impairment of vasodilator mechanisms, (3) increased response of dysfunctional vascular smooth muscle cells to vasoconstrictor stimuli, or (4) variable combination of these mechanisms.

3) In animal models, and possibly in unstable patients, the severity of stenosis may also be modulated by platelet aggregates.


Related Discussions:- Coronary flow limiting stenoses

Explain what is prosthetic valve endocarditis, Explain what is Prosthetic V...

Explain what is Prosthetic Valve Endocarditis (PVE) ? Prosthetic valve endocarditis (PVE) is called EARLY when symptoms begin within 60 days of surgery and LATE when the onset

Point out some guidelines for breast-feeding, Point out some Guidelines for...

Point out some Guidelines for breast-feeding? 1) Follow demand feeding of the baby instead of a fixed schedule. 2) Initiate breast-feeding within 2 h after a normal delivery

Why is maternal milk important for the immune protection, Why is maternal m...

Why is maternal milk important for the immune protection of the baby? Besides being nutritionally significant, maternal milk participates in the defense of the baby against inf

Myocarditis, Myocarditis Myocarditis is inflammation of the myocardiu...

Myocarditis Myocarditis is inflammation of the myocardium, of the heart muscles. i) Causes Infection: . Wrus, bacteria, fungus, parasites Non-infection: Radi

What is polymerase chain reaction, Which of the following is a false statem...

Which of the following is a false statement regarding Polymerase Chain Reaction (PCR)? A. PCR is a modified version of cellular replication that is used to amplify small amount

What is the difference between haploid and diploid, What is the difference ...

What is the difference between haploid and diploid? why are so many anesthesias fat solvents Why is it important for core body temperature to stay more constant than skin tem

How to indicate an av block, During the course of a physiology laboratory, ...

During the course of a physiology laboratory, a student finds that her PR interval is 0.24 second. Concerned, she takes her own ECG again an hour later and sees an area of the ECG

Explain about the dna viruses - carcinogenic, Explain about the DNA viruses...

Explain about the DNA viruses - Carcinogenic? The three DNA viruses found to cause human cancers are EBV, HBV and HPV. What are these? Let us find out. Epstein-Barr viru

Explain the genioglossus, Genioglossus Originates from superior genial ...

Genioglossus Originates from superior genial tubercles which are located near the crest of the alveolar ridge in atrophic mandible. Therefore, one should be aware of it during

Explain assessment of iron status - serum ferritin, Explain assessment of i...

Explain assessment of iron status - Serum Ferritin? Serum Ferritin: This method is indicative of iron stores. As we know, a long term negative iron balance first results in dep

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd