Coronary flow limiting stenoses, Biology

Assignment Help:

Coronary Vasoconstriction

1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor changes. Fixed flow limiting stenoses present smooth muscle cell atrophy and/or plaque rigidity and are associated with the predictable ischaemic threshold and a stable pattern of effort related myocardial ischaemia.

Dynamic stenoses are usually eccentric, with compliant segments of the wall and preserved muscular media, and are associated with a variable ishaemic threshold.

2) Vasoconstriction at the site of stenoses may result from (1) neural vasoconstrictor stimuli, (2) impairment of vasodilator mechanisms, (3) increased response of dysfunctional vascular smooth muscle cells to vasoconstrictor stimuli, or (4) variable combination of these mechanisms.

3) In animal models, and possibly in unstable patients, the severity of stenosis may also be modulated by platelet aggregates.


Related Discussions:- Coronary flow limiting stenoses

Describe cardiac rewabilptation and its various effects, Describe cardiac r...

Describe cardiac rewabilptation and its various effects ? A survival benefit cannot be attributed solely to exercise training because many studies involved multifunctional inte

Explain the function of the right ventricle, Q. What is the function of the...

Q. What is the function of the right ventricle? To where does the right ventricle pump the venous blood? The venous blood is carried as of the right ventricle to the lungs by t

What is hyperhomocysteinaemia, What is Hyperhomocysteinaemia ? Homocyst...

What is Hyperhomocysteinaemia ? Homocysteine has been considered as a risk factor for Cardio-vascular diseases because of many epidemiological and observational studies showing

What is glycolysis, What is glycolysis? What are the products of this proce...

What is glycolysis? What are the products of this process? Glycolysis, the first stage of the aerobic cell respiration, is a process in which glucose is degraded (broken) to fo

Fertilization in earthworm, In earthworms, when the ovaries mature, the cli...

In earthworms, when the ovaries mature, the clitellum secretes a viscous substance in the form of a girdle. This girdle hardens in to a cocoon around the clitellum. The ova are dis

Bacterial artificial chromosome (bac), Bacterial artificial chromosome (BAC...

Bacterial artificial chromosome (BAC) is a chromosome-like structure, made by genetic engineering. BAC is a cloning vector able to carrying between 100 and 300 kilo bases of targe

Final atp count in both prokaryotes and eukaryotes, Degrade a monoglyceride...

Degrade a monoglyceride that has an 18-carbon fatty acid attached to it by Ester bonds. You will have to degrade the glycerol component followed by the fatty acid in presence of O2

Viral diseases, Nature of viral diseases Viral diseases are manifested...

Nature of viral diseases Viral diseases are manifested in acute, sub-acute or chronic forms, as frank clinical cases or as latent infections, some of which are fatal. These di

Explain the canal obstruction - endodontic retreatment, Explain the Canal O...

Explain the Canal Obstruction File work shorter than the normal apical and feel a great resistance to reach true length. a. A retained instrument o Canal calcification b.

#virus, how do viruses reproduce

how do viruses reproduce

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd