Coronary flow limiting stenoses, Biology

Assignment Help:

Coronary Vasoconstriction

1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor changes. Fixed flow limiting stenoses present smooth muscle cell atrophy and/or plaque rigidity and are associated with the predictable ischaemic threshold and a stable pattern of effort related myocardial ischaemia.

Dynamic stenoses are usually eccentric, with compliant segments of the wall and preserved muscular media, and are associated with a variable ishaemic threshold.

2) Vasoconstriction at the site of stenoses may result from (1) neural vasoconstrictor stimuli, (2) impairment of vasodilator mechanisms, (3) increased response of dysfunctional vascular smooth muscle cells to vasoconstrictor stimuli, or (4) variable combination of these mechanisms.

3) In animal models, and possibly in unstable patients, the severity of stenosis may also be modulated by platelet aggregates.


Related Discussions:- Coronary flow limiting stenoses

Why plants need to do exchange gases with the environment, Why plants need ...

Why plants need to do exchange gases with the environment? The Plants need to do gas exchange because they create aerobic cellular respiration (like animals) and they need to r

Explain about insulin concentrations, Insulin Concentrations The doctor...

Insulin Concentrations The doctor always prescribes insulin dosage in units. Thus all types of insulin (crystalline, NPH, Lente, and so forth) is available in 10-ml vials that

State the term - symbolic representation, State the term - Symbolic represe...

State the term - Symbolic representation Symbolic representation is the representation of both the external and internal world through symbols and has been discussed in relatio

Does natural selection produce an effect directly on genes, Does natural se...

Does natural selection produce an effect directly on genes, on genotypes, or on phenotypes? Explain please.

.phylum pisces, wt is an air bladder and its function wt is catadromous and...

wt is an air bladder and its function wt is catadromous and anadromus migration

Phenology of different species, Phenology of Different Species The phe...

Phenology of Different Species The phenology of different species present in a community may differ from each other significantly. It is these phenological changes which give

Infructescences- pseudofruits and parthenocarpic fruits, What are the infru...

What are the infructescences, pseudofruits and parthenocarpic fruits? The Infructescences are aggregated fruits formed from inflorescences, aggregated flowers. Grape clusters a

Differance among subphylum chaetognatha and urochordata, Explain differance...

Explain differance between Subphylum Chaetognatha and Subphylum Urochordata? Subphylum Chaetognatha: Larval stages of this small group share some of the characteristics with

Alternative processing: alternative splicing, Various cases  are  now  know...

Various cases  are  now  known  where  variant  tissues  splice  the  main  RNA transcript of a single gene by instead pathways, where the exons which are lost and those which are

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd