Coronary flow limiting stenoses, Biology

Assignment Help:

Coronary Vasoconstriction

1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor changes. Fixed flow limiting stenoses present smooth muscle cell atrophy and/or plaque rigidity and are associated with the predictable ischaemic threshold and a stable pattern of effort related myocardial ischaemia.

Dynamic stenoses are usually eccentric, with compliant segments of the wall and preserved muscular media, and are associated with a variable ishaemic threshold.

2) Vasoconstriction at the site of stenoses may result from (1) neural vasoconstrictor stimuli, (2) impairment of vasodilator mechanisms, (3) increased response of dysfunctional vascular smooth muscle cells to vasoconstrictor stimuli, or (4) variable combination of these mechanisms.

3) In animal models, and possibly in unstable patients, the severity of stenosis may also be modulated by platelet aggregates.


Related Discussions:- Coronary flow limiting stenoses

Explain the nucleic acid is the transforming agent or not, Fredrick Griffit...

Fredrick Griffith published a series of experiments that collectively were dubbed "The Transforming Principle" in 1928. Which of the following prevented him from being able to decl

Name the different systems of the body, The Different systems of the body a...

The Different systems of the body are: 1) Nervous System 2) Respiratory System 3) Cardiovascular System 4) Neurological and Sensory System 5) Gastrointestinal Syste

Define the characteristics that are seen in rickets, Define the characteris...

Define the characteristics that are seen in Rickets? The following characteristics are seen in fully developed cases of rickets: 1) In case of young infants, delayed closure

Bubble oxygenators type of oxygenators , Bubble Oxygenators: These ha...

Bubble Oxygenators: These have a mixing chamber where venous blood is collected and from the bottom end micro bubbles of oxygen are passed and as they rise to the top, gas ex

Sporophytic and gametophytic self-incompatibility, Sporophytic and Gametoph...

Sporophytic and Gametophytic Self-Incompatibility Besides the categories based on morphology, self incompatibility can be further classified into sporophytic or gametophytic t

Describe the positive end expiratory pressure, Describe the Positive End Ex...

Describe the Positive End Expiratory Pressure (PEEP)? A positive pressure may be applied at the end of the expiratory phase during mechanical ventilation, instead of allowing t

Do fats with one or more ''kinky'' tail fatty acids, Do fats with one or mo...

Do fats with one or more 'kinky' tail fatty acids tend to be solid or liquid at room temperature? These are found in triglycerides forming what? Solid fats or oils? Is it opposite

Digestive system, which enzymes are required for digestion in cockroach?

which enzymes are required for digestion in cockroach?

Theory of embryology - pre-formation theory, PR E FORMATION THEORY - ...

PR E FORMATION THEORY - Proposed by Marcello Malpighi. Studied chick egg and proposed his work in "De ova-incubato". According this different part of embryo previousl

Explain the genioglossus, Genioglossus Originates from superior genial ...

Genioglossus Originates from superior genial tubercles which are located near the crest of the alveolar ridge in atrophic mandible. Therefore, one should be aware of it during

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd