Coronary flow limiting stenoses, Biology

Assignment Help:

Coronary Vasoconstriction

1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor changes. Fixed flow limiting stenoses present smooth muscle cell atrophy and/or plaque rigidity and are associated with the predictable ischaemic threshold and a stable pattern of effort related myocardial ischaemia.

Dynamic stenoses are usually eccentric, with compliant segments of the wall and preserved muscular media, and are associated with a variable ishaemic threshold.

2) Vasoconstriction at the site of stenoses may result from (1) neural vasoconstrictor stimuli, (2) impairment of vasodilator mechanisms, (3) increased response of dysfunctional vascular smooth muscle cells to vasoconstrictor stimuli, or (4) variable combination of these mechanisms.

3) In animal models, and possibly in unstable patients, the severity of stenosis may also be modulated by platelet aggregates.


Related Discussions:- Coronary flow limiting stenoses

Gastrulation in some animals, Gastrulation in some Animals As mentione...

Gastrulation in some Animals As mentioned before gastrulation marks the beginning of morphogenesis that is development of body form and organisation of cells in the embryo. By

Define nutritional needs during recovery, Define nutritional needs During R...

Define nutritional needs During Recovery? Here, let us discuss what should be the nutritional goals based on the physiological aspects involved. Goals: The main emphasis mus

What is temperate grasslands, What is Temperate Grasslands? Grasslands ...

What is Temperate Grasslands? Grasslands are known by their common names in different regions of the world, such as the plains or prairies in North America, the steppe in Asia,

Determine the process of rna editing, Which of the following is a true stat...

Which of the following is a true statement regarding the process of RNA editing? A. RNA editing alters the sequence of the mRNA message thereby permitting for an enhance in pro

Fatty acid breakdown, Fatty acids are a very significant adenosine triphosp...

Fatty acids are a very significant adenosine triphosphate (ATP) and source of energy for various cellular organisms. Over fatty acids, glucose and other nutrients can be stored eff

Water stress - responses of plants to stress, Water Stress - Responses of P...

Water Stress - Responses of Plants to Stress Water stress in a plant can result from drought, excess salinity in the soil and very low or high temperatures. It has been found

Define the normal squid intracellular saline, At 1 AM, a researcher places ...

At 1 AM, a researcher places a healthy squid giant axon in a bath of normal squid physiological extracellular saline and internally perfuses the axon with normal squid intracellula

Dietary recommendations in celiac disease, Q. Dietary Recommendations in ce...

Q. Dietary Recommendations in celiac disease? The only dietary treatment for celiac disease is to follow a gluten-free diet. For most such a diet improves symptoms, heals inte

Define quantitative procedures in carbohydrates, Define Quantitative Proced...

Define Quantitative Procedures in Carbohydrates? You have learnt how to identify some individual monosaccharides, disaccharides and polysaccharides. However, if we were asked t

What are the maintenance sequences of implant, Maintenance sequences of imp...

Maintenance sequences of implant Achieving a successful result with the treatment is only half the battle won. The main challenge is maintain that result over a long period of

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd