Coronary flow limiting stenoses, Biology

Assignment Help:

Coronary Vasoconstriction

1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor changes. Fixed flow limiting stenoses present smooth muscle cell atrophy and/or plaque rigidity and are associated with the predictable ischaemic threshold and a stable pattern of effort related myocardial ischaemia.

Dynamic stenoses are usually eccentric, with compliant segments of the wall and preserved muscular media, and are associated with a variable ishaemic threshold.

2) Vasoconstriction at the site of stenoses may result from (1) neural vasoconstrictor stimuli, (2) impairment of vasodilator mechanisms, (3) increased response of dysfunctional vascular smooth muscle cells to vasoconstrictor stimuli, or (4) variable combination of these mechanisms.

3) In animal models, and possibly in unstable patients, the severity of stenosis may also be modulated by platelet aggregates.


Related Discussions:- Coronary flow limiting stenoses

Show gastrointestinal diseases and disorders, Q. Show Gastrointestinal Dise...

Q. Show Gastrointestinal Diseases and Disorders? Before discussing the many gastrointestinal problems, it is useful to understand the basic physiology of the gastrointestinal t

Tissue synthesis for wound healing in nutritional care, Explain the Tissue ...

Explain the Tissue Synthesis for Wound Healing in Nutritional Care? Tissue proteins are synthesized only by amino acids brought to the tissues by circulating blood. The necessa

What are presbyopia and astigmatism, What are presbyopia and astigmatism? ...

What are presbyopia and astigmatism? Presbyopia is the visual impairment in which there is loss of the cililary muscle strength therefore reducing the capability of the crystal

What is pulmonary stenosis, Pulmonary Stenosis :  The obstruction may be v...

Pulmonary Stenosis :  The obstruction may be valvar, infundibular or supra valvar.

Define tests to measure muscular strength and endurance, Define Tests to Me...

Define Tests to Measure Muscular Strength and Endurance? It is important to first understand the difference between muscular strength and endurance. To know the muscular streng

#to work as expert, Ask question #process for work as expert#

Ask question #process for work as expert#

Types of passive transport, Simple diffusion Only comparatively small u...

Simple diffusion Only comparatively small uncharged or hydrophobic molecules (H2O, O2, and CO2, other gases, urea and ethanol)   cross   the lipid   bilayer   through simple

Immunity, We have no antibodies against any blood group when we are born st...

We have no antibodies against any blood group when we are born still we say that some blood groups are incompatible for us.why?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd