Coronary flow limiting stenoses, Biology

Assignment Help:

Coronary Vasoconstriction

1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor changes. Fixed flow limiting stenoses present smooth muscle cell atrophy and/or plaque rigidity and are associated with the predictable ischaemic threshold and a stable pattern of effort related myocardial ischaemia.

Dynamic stenoses are usually eccentric, with compliant segments of the wall and preserved muscular media, and are associated with a variable ishaemic threshold.

2) Vasoconstriction at the site of stenoses may result from (1) neural vasoconstrictor stimuli, (2) impairment of vasodilator mechanisms, (3) increased response of dysfunctional vascular smooth muscle cells to vasoconstrictor stimuli, or (4) variable combination of these mechanisms.

3) In animal models, and possibly in unstable patients, the severity of stenosis may also be modulated by platelet aggregates.


Related Discussions:- Coronary flow limiting stenoses

Nicotinic acid or niacin, Niacin affects all lipid parameters favorably. It...

Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of freq

Carbonization process, When coal is heated strongly in absence of air, it f...

When coal is heated strongly in absence of air, it forms a strong, porous, dense and coherent mass known as coke. This process of conversion of coal into coke is called carbonzatio

EMBRYOLOGY.., WHAT IS RECAPITULATION THEORY OF EMBRYOLOGY?AND WHAT IS EMBRY...

WHAT IS RECAPITULATION THEORY OF EMBRYOLOGY?AND WHAT IS EMBRYOLOGY

Explain the nutritional and functional role of iron, Minerals :- Iron ...

Minerals :- Iron Food Source      Cereals, legumes, meat contamination from iron utensils and soil Nutritional Functional role Essential nutrient: Deficiency lead

Explain about the infantile beriberi, Explain about the Infantile beriberi?...

Explain about the Infantile beriberi? Infantile beriberi is commonly seen in many South-East Asian countries where the diets consist mostly of "polished rice" and are deficient

What is the magnitude n, Three point charges are located at the corners of ...

Three point charges are located at the corners of an equilateral triangle. Find the magnitude and direction of the net electric force on the 1.60 uC charge. (Let A = 1.60 uC, B= 6.

Explain subclavian flap aortoplasty, Explain Subclavian Flap Aortoplasty ? ...

Explain Subclavian Flap Aortoplasty ? Initial steps are same as for resection and end-to-end anastomosis. After exposing a the entire length of intra thoracic segment of left s

Determine what are the genotypes of the parents, 1. In chickens rose comb (...

1. In chickens rose comb ( R ) is dominant over single comb ( r ). A rose-combed male is mated to a rose-combed female. Eighteen chicks are produced, ten of which are rose-combed,

What is mass transportation across the cell membrane, What is mass transpor...

What is mass transportation across the cell membrane? Mass transportation is the entrance or the exiting of substances in or from the cell engulfed by portions of membrane. The

Continuous wave doppler, When a ventricQlar septa1 defect (VSD) is present,...

When a ventricQlar septa1 defect (VSD) is present, with no aortic stenosis, the peak velocitgr  across the defect reflects the difference in pressure between the right ventricle an

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd