Coronary flow limiting stenoses, Biology

Assignment Help:

Coronary Vasoconstriction

1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor changes. Fixed flow limiting stenoses present smooth muscle cell atrophy and/or plaque rigidity and are associated with the predictable ischaemic threshold and a stable pattern of effort related myocardial ischaemia.

Dynamic stenoses are usually eccentric, with compliant segments of the wall and preserved muscular media, and are associated with a variable ishaemic threshold.

2) Vasoconstriction at the site of stenoses may result from (1) neural vasoconstrictor stimuli, (2) impairment of vasodilator mechanisms, (3) increased response of dysfunctional vascular smooth muscle cells to vasoconstrictor stimuli, or (4) variable combination of these mechanisms.

3) In animal models, and possibly in unstable patients, the severity of stenosis may also be modulated by platelet aggregates.


Related Discussions:- Coronary flow limiting stenoses

Renal parenchymal disease, Renal parenchymal disease is the commonest cause...

Renal parenchymal disease is the commonest cause of secondary hypertension.  Hypertensive and diabetic nephropathy and chronic glomerulonephritis are the main causes. Eventually, t

Explain identification of cancer cells from normal cells, Explain Identific...

Explain Identification of Cancer Cells from Normal Cells? Cancer cells can be distinguished from normal cells by examining them under a microscope. In a specific tissue cancer

Deficiency diseases-evaluation of production diseases, Evaluation of produc...

Evaluation of production diseases Generally, production diseases are acute states and respond dramatically to administration of a deficient nutrient or metabolite. The nutriti

Genetics, The involuntary muscle movement is also genetical sk question #M...

The involuntary muscle movement is also genetical sk question #Minimum 100 words accepted#

Explain adverse effects of voriconazole, Adverse Effects of voriconzole ...

Adverse Effects of voriconzole Transient visual disturbances, including blurred vision, photophobia and altered perception of color or image, are common with voriconazole. Rash

How does the Cornea work, How does the Cornea work, I heard that it is like...

How does the Cornea work, I heard that it is like a motor, however i''m not too sure... because a motor is in vehicle and has piston, and the Cornea is in our eyes and... Well does

Pericardial window through left antero lateral thoracotomy, Pericardial Win...

Pericardial Window Through Left Antero Lateral Thoracotomy :  A small left antero lateral thoracotomy is done through the 5"' intercostal space. A pericardial windo

Illustrate basic working of pineal gland, Q. What is the pineal gland? ...

Q. What is the pineal gland? The pineal gland also known as epiphysis or pineal body is situated centrally in the head. It secretes the hormone melatonin. A hormone produced at

Records and reports - nursing service administration, RECORDS AND REPORTS: ...

RECORDS AND REPORTS: The principles of administration are described as  'POSDCORB'.  The  'R' stands for recording and reporting. Recording and reporting is related to all oth

Enumerate about the wisconsin card sorting test, Enumerate about the Wiscon...

Enumerate about the Wisconsin Card Sorting Test Verbal memory, non verbal memory etc. are tested through the presentation of stimuli such as verbal learning test, selective rem

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd