Coronary flow limiting stenoses, Biology

Assignment Help:

Coronary Vasoconstriction

1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor changes. Fixed flow limiting stenoses present smooth muscle cell atrophy and/or plaque rigidity and are associated with the predictable ischaemic threshold and a stable pattern of effort related myocardial ischaemia.

Dynamic stenoses are usually eccentric, with compliant segments of the wall and preserved muscular media, and are associated with a variable ishaemic threshold.

2) Vasoconstriction at the site of stenoses may result from (1) neural vasoconstrictor stimuli, (2) impairment of vasodilator mechanisms, (3) increased response of dysfunctional vascular smooth muscle cells to vasoconstrictor stimuli, or (4) variable combination of these mechanisms.

3) In animal models, and possibly in unstable patients, the severity of stenosis may also be modulated by platelet aggregates.


Related Discussions:- Coronary flow limiting stenoses

Processing grains and oil seeds for animal feeding, Processing grains and o...

Processing grains and oil seeds for animal feeding Simple processing of grains such as grinding facilitates the digestion particularly in cattle and buffaloes. Fine grinding of

To show the effects of yeast on dough, To show the effects of yeast on doug...

To show the effects of yeast on dough Mix together some sugar, water and flour in the proportions to make good bread dough. Divide the dough into two equivalent parts. Stir a h

Acute aortic regurgitation-types of regurgitation, Acute Aortic Regurgitati...

Acute Aortic Regurgitation :  The most dramatic presentation occurs in dissection of the aortic root. Endocarditis of the native or prosthetic aortic valve may also lead to a

Explain process of fatty acid composition, Explain process of Fatty acid co...

Explain process of Fatty acid composition We know fats/oils are made up of fatty acids. The number, position and geometry of double bonds within the fatty acids affect the rate

What is radiographic assessment, What is Radiographic Assessment Radio...

What is Radiographic Assessment Radiographic Assessment: Radiographic examination is very different with implants than with teeth. Radiographs are frequently used in implant

Terrestrial biomes of the world, The primary factors that influence the for...

The primary factors that influence the formation of these biomes are climatic, like precipitation, temperature, seasonal extremes and winds. However, topography and light are also

Define tests of cardiovascular endurance, Define Tests of Cardiovascular E...

Define Tests of Cardiovascular Endurance? Cardiovascular endurance or aerobic fitness is the ability to exercise continuously for extended periods without tiring. It can be me

Effects of cardiogenic pulmonary edema, Effects of Cardiogenic Pulmonary Ed...

Effects of Cardiogenic Pulmonary Edema Interference with oxygen transfer in the lungs Depression arterial oxygen tension Sense of suffocation and oppression in the

What are the dominate phenotype, There is a population of 100 frogs. 20 are...

There is a population of 100 frogs. 20 are heterozygotes, 30 are homozygous recessive, 25 are homozygous dominate. What is the frequency of the dominate allele? The recessive allel

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd