Coronary flow limiting stenoses, Biology

Assignment Help:

Coronary Vasoconstriction

1) Coronary flow limiting stenoses are caused by concentric or eccentric artherosclerotic plaques, with or without potential for local vasomotor changes. Fixed flow limiting stenoses present smooth muscle cell atrophy and/or plaque rigidity and are associated with the predictable ischaemic threshold and a stable pattern of effort related myocardial ischaemia.

Dynamic stenoses are usually eccentric, with compliant segments of the wall and preserved muscular media, and are associated with a variable ishaemic threshold.

2) Vasoconstriction at the site of stenoses may result from (1) neural vasoconstrictor stimuli, (2) impairment of vasodilator mechanisms, (3) increased response of dysfunctional vascular smooth muscle cells to vasoconstrictor stimuli, or (4) variable combination of these mechanisms.

3) In animal models, and possibly in unstable patients, the severity of stenosis may also be modulated by platelet aggregates.


Related Discussions:- Coronary flow limiting stenoses

Errors in fertilization, ERRORS IN FERTILIZATION  - 1.       Polyspe...

ERRORS IN FERTILIZATION  - 1.       Polyspermy - When more than one sperms are fused in an ovum, this condition is called polyspermy. 2.       Polygynae - During oogen

Anterior leaflet procedure-technique of operation, Anterior Leaflet Procedu...

Anterior Leaflet Procedure: Repair is more difficult and less successful. Previously, a triangular excision of the anterior leaflet used to be done for prolapse and rupture of

Food and diet, 3 main ways in which the body uses food

3 main ways in which the body uses food

What is implant therapy, What is Implant therapy Successful implant th...

What is Implant therapy Successful implant therapy requires systematic thorough and meticulous planning to determine the ultimate prognosis and end result that will satisfy th

Pbpk modeling during human drug development, Early human studies are normal...

Early human studies are normally conducted in healthy subjects to assess acute safety and, if applicable, to monitor biochemical and pharmacological responses. These studies also p

Phylum sarcomastigophora - protozoan, Phylum Sarcomastigophora Locomo...

Phylum Sarcomastigophora Locomotory organelles - flagella, pseudopodia or both types, usually with one type of nucleus; typically no spore formation, sexual reproduction thro

Pneumonia, Pneumonia: Pneumonia is an inflammation with consolidation ...

Pneumonia: Pneumonia is an inflammation with consolidation  of  the parenchyma of  the lung. It occurs most commonly in infants and young children and may occur as primary dis

Explain wild-type fruitfly drosophila melanogaster, A cross among wild-type...

A cross among wild-type fruitfly Drosophila melanogaster  [normal bristles and grey body (s+s, e+ e)] with a mutant fly [short bristles and ebony body (ss ee)] produces following p

Express the three functional classifications of joints, In general compare ...

In general compare and contrast the three functional classifications of joints according to movement.

Respiration in cockroach, what is the chemical reaction of respiration in c...

what is the chemical reaction of respiration in cockroach?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd