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Continual reassessment method: An approach which applies Bayesian inference for determining the maximum tolerated dose in a phase I trial. The method starts by assuming a logistic regression model for the dose-toxicity relationship and the prior distribution for the parameters. Once each patient's toxicity result becomes available posterior distribution of the parameters is recomputed and used to estimate probability of the toxicity at each of a series of dose levels.
The scatter plots of SRES1, RESI1 versus totexp demonstrates that there is non-linear relationship that exists as most of the points are below and above zero. The scatter plots sho
I want to get the quotation of my on-line assignment its based on 1000 words. lecturer provide the video links and we have to watch the videos and highlights the key points also de
Hill-climbing algorithm is an algorithm which is made in use in those techniques of cluster analysis which seek to find the partition of n individuals into g clusters by optimizin
The procedure for clustering variables in the multivariate data, which forms the clusters by performing one or other of the below written three operations: * combining two varia
The time series for RESI1, HI1 and COOK1 have appeared again with different outlier values even though the 17 outliers found early were removed.
methods of determining trend in time series?
Non-identified response is a term used to signify censored observations in survival data, which are not independent of the endpoint of the interest. Such observations can happen f
A directed graph is simple if each ordered pair of vertices is the head and tail of at most one edge; one loop may be present at each vertex. For each n ≥ 1, prove or disprove the
Lattice distribution : A class of probability distributions to which most of the distributions for discrete random variables used in statistics belongs. In such type of distributio
Nested design is the design in which levels of one or more factors are subsampled within one or more other factors such that, for instance, each level of a factor B happens at onl
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