Continual reassessment method, Advanced Statistics

Assignment Help:

Continual reassessment method: An approach which applies Bayesian inference for determining the maximum tolerated dose in a phase I trial. The method starts by assuming a logistic regression model for the dose-toxicity relationship and the prior distribution for the parameters. Once each patient's toxicity result becomes available posterior distribution of the parameters is recomputed and used to estimate probability of the toxicity at each of a series of dose levels.


Related Discussions:- Continual reassessment method

Markov chains.., a shop is selling laptops at regular price and at half pri...

a shop is selling laptops at regular price and at half price.If the laptops are regular price a day they will be at regular price tha day after with proba 2/3, if the laptops are a

T test , How do I report the results in the table?

How do I report the results in the table?

Please answer this question, How large would the sample need to be if we ar...

How large would the sample need to be if we are to pick a 95% confidence level sample: (i) From a population of 70; (ii) From a population of 450; (iii) From a population of 1000;

Omitted covariates, Omitted covariates is a term generally found in the co...

Omitted covariates is a term generally found in the connection with regression modelling, where the model has been incompletely specified by not including significant covariates.

Gabor regression, This is an approach to the modelling of time-frequency su...

This is an approach to the modelling of time-frequency surfaces which consists of a Bayesian regularization scheme in which the prior distributions over the time-frequency coeffici

Data fusion, The act of combining data from heterogeneous sources with the ...

The act of combining data from heterogeneous sources with the intent of extracting information that would not be available for any single source in isolation. An example is the com

Path analysis, Path analysis  is  a device for evaluating the interrelat...

Path analysis  is  a device for evaluating the interrelationships among the variables by analyzing their correlational structure. The relationships between the variables are man

Survey Design, Hello, I have a solution for a Survey Design (proposal) assi...

Hello, I have a solution for a Survey Design (proposal) assignment and looking for an expert that can look at it and correct it in case if it is wrong. Do you have this kind of ser

Determine the maximum amount of the commodity, A manufacturing company has ...

A manufacturing company has two factories F 1 and F 2 producing a certain commodity that is required at three retail outlets M 1 , M 2 and M 3 . Once produced, the commodity is

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd