Clinical trials, Advanced Statistics

Assignment Help:

Clinical trials: Medical experiments designed to assess which of two or more treatments is much more effective. It is based on one of the oldest philosophy of the scienti?c research, namely that the new information is attained from the comparison of the alternative states. The three main components of a clinical trial are given below:

* Comparison of the group or set of patients given the treatment under the investigation with another group or set of the patients given either an older or the standard treatment, in one exists, or an 'inert treatment' commonly known as the placebo (or the control group).

Some trials might include more than two groups.

* A way of assigning patients to the treatment and control groups or sets.

* A measure of the outcome, that is a response variable.

One of the most significant aspects of the clinical trial is the question of how the patients should be allocated to the treatment and the control group. The objective in the allocation is that the treatment group and control group should be similar in all respects except treatment taken. As a result the clinical trial is more likely to give an unbiased estimate of the difference between the two treatments. The most suitable (perhaps only suitable) method of the allocation is randomization leading to randomized clinical trials, the gold standard for the treatment assessment.

 


Related Discussions:- Clinical trials

Range, Range is the difference between the largest and smallest observatio...

Range is the difference between the largest and smallest observations in the data set. Commonly used as an easy-to-calculate measure of the dispersion in the set of observations b

Cluster sampling, Cluster sampling : A method or technique of sampling in w...

Cluster sampling : A method or technique of sampling in which the members of the population are arranged in groups (called as 'clusters'). A number of clusters are selected at the

Fuzzy set theory, A radically different approach of dealing with the uncert...

A radically different approach of dealing with the uncertainty than the traditional probabilistic and the statistical methods. The necessary feature of the fuzzy set is a membershi

Asymmetric proximity matrices, Asymmetric proximity matrices : Proximity ma...

Asymmetric proximity matrices : Proximity matrices in which the non-diagonal elements, in the ith row and jth column and the jth row and ith column, are not essentially equal. Exam

Minimum volume ellipsoid, Minimum volume ellipsoid is a term for ellipsoid...

Minimum volume ellipsoid is a term for ellipsoid of the minimum volume which covers some specified proportion of the set of multivariate data. It is commonly used to construct rob

Machine learning, Machine learning  is a term which literally means the ab...

Machine learning  is a term which literally means the ability of a machine to recognize patterns which have occurred repetitively and to improve its performance based on the past

Random allocation, Random allocation is a technique for creating the treat...

Random allocation is a technique for creating the treatment and control groups particularly in accordance of the clinical trial. Subjects receive the active treatment or the place

Intercropping experiments, Intercropping experiments are the experiments i...

Intercropping experiments are the experiments including growing two or more crops at same time on the same patch of land. The crops are not required to be planted nor harvested at

Line-intersect sampling, Line-intersect sampling is a technique of unequal...

Line-intersect sampling is a technique of unequal probability sampling for selecting the sampling units in the geographical area. A sample of lines is drawn in a study area and, w

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd