Chronic bronchitis, Biology

Assignment Help:

Chronic Bronchitis

Chronic Bronchitis is defined clinically as hypersecretion of mucus and recurrent episode of productive cough for a period of 3 months per year at least two consecutive years. 

Pathophysiology

First there is glandular hypertrophy. Mucous gland hypertrophy and hyperplasia from chronic irritations cause excessive mucus production. The excessive mucus and impaired ciliary movement associated with chronic bronchitis increase susceptibility to infection. As infection progress, the epithelial cells produce a mucopurulent exudates in the lumen or the disease may progress to ulceration and destruction of the bronchial wall. The peribronchial fibrosis and the presence of granulation tissue result in stenosis and airway obstruction.

Second the bronchial wall tissue changes, mucosal ocdema and excessive mucus production, all increase airway resistance in persons with chronic bronchitis. Excess mucus may also cause bronchospasm. 

Third the pathophysiologic changes may impair the ability of lungs to exchange 0, and CO, leading to ventilation-perfusion mismatching at the alveolar-capillary membrane. Obstructed airways may lead to atelectasis which further diminishes the surface are a available for respiration. Fourth the right ventricular decompensation or corpulmonale may result.


Related Discussions:- Chronic bronchitis

Explain about the solar dryers, Explain about the Solar Dryers? There a...

Explain about the Solar Dryers? There are so many different designs for solar dryers, these range from simple convection dryers, cabinet dryers, shelf dryers to more complicate

Explain healthcare burden of heart diseases, Explain Healthcare Burden OF H...

Explain Healthcare Burden OF HEART DISEASES? CAD and its complications use up a substantial portion of the scarce healthcare resource of the country. It has been reported that

Define contains permitted synthetic food colour, Normal 0 fa...

Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4

Species concept, SPECIE S CONCEPT - According to Davis and Heywood...

SPECIE S CONCEPT - According to Davis and Heywood species define as assemblage of individuals with morphological features in common and separable from other such assembla

Detail description of connective tissue proper, CONNECTIVE TISSUE PROPER - ...

CONNECTIVE TISSUE PROPER - 1 .      AREOLAR TISSUE ( = Loose connective tissue) - Widely distributed connective tissue in the animal body. It consists of ground sub

Left main coronary artery disease, Left Main Coronary Artery Disease (LMCA...

Left Main Coronary Artery Disease (LMCAD) : Stenosis of 50 per cent or more of the left main coronary artery is an indication. If or surgery. Results of medical management are ver

Salmonellosis, Salmonellosis The genus Salmonella comprises nearly 2500...

Salmonellosis The genus Salmonella comprises nearly 2500 serovars, traditionally based on Kauffman-White scheme in which H (flagelar) and O (somatic) antigens determine the ser

Empyema, Empyema: Empyema is accumulation of  thick pus in the pleural...

Empyema: Empyema is accumulation of  thick pus in the pleural cavity. Primary infection of pleura does not arise so the pathology may either be in chest wall, mediastinum or t

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd