Chronic bronchitis, Biology

Assignment Help:

Chronic Bronchitis

Chronic Bronchitis is defined clinically as hypersecretion of mucus and recurrent episode of productive cough for a period of 3 months per year at least two consecutive years. 

Pathophysiology

First there is glandular hypertrophy. Mucous gland hypertrophy and hyperplasia from chronic irritations cause excessive mucus production. The excessive mucus and impaired ciliary movement associated with chronic bronchitis increase susceptibility to infection. As infection progress, the epithelial cells produce a mucopurulent exudates in the lumen or the disease may progress to ulceration and destruction of the bronchial wall. The peribronchial fibrosis and the presence of granulation tissue result in stenosis and airway obstruction.

Second the bronchial wall tissue changes, mucosal ocdema and excessive mucus production, all increase airway resistance in persons with chronic bronchitis. Excess mucus may also cause bronchospasm. 

Third the pathophysiologic changes may impair the ability of lungs to exchange 0, and CO, leading to ventilation-perfusion mismatching at the alveolar-capillary membrane. Obstructed airways may lead to atelectasis which further diminishes the surface are a available for respiration. Fourth the right ventricular decompensation or corpulmonale may result.


Related Discussions:- Chronic bronchitis

Biphasic graph, how can i explain the biphasic graph i get fom combination ...

how can i explain the biphasic graph i get fom combination of two drugs?

Describe about cardiac examination, Describe about cardiac examination? ...

Describe about cardiac examination? Physical examination of the cardiovascular system is mainly discussed under four headings i.e., inspection, palpation, percussion and auscul

Variations, VARI A TION S - Defined as "dissimilarities of featur...

VARI A TION S - Defined as "dissimilarities of features among members of the same species". Offsprings of same parent are different and also differ from their parent.

History of cell biology, HISTORY OF CELL BIOLOGY Scientific knowledge gro...

HISTORY OF CELL BIOLOGY Scientific knowledge grows with the development of new tools and techniques for studying various physical and biological processes. This is true also of t

Gonad glands, what are the gonad gland disorders and what do they do

what are the gonad gland disorders and what do they do

Differences between budding and fission, Differences between Budding and Fi...

Differences between Budding and Fission Both budding and fission are identical in at least one way in that the young ones produced by these procedures are the result of direct

Define the open loop system, Situation in which a closed loop negative feed...

Situation in which a closed loop negative feedback system is  converted to an open loop system?     A.  A disease that destroys all the adenylyl cyclase and all the cAMP in the

How the visual images are projected, Since the visual images are projected ...

Since the visual images are projected in an inverted manner on the retina why don't we see things upside down? As the crystalline lens is a convex spherical lens it forms inver

Another type of soil for bacteria gardens, Another type of soil for bacteri...

Another type of soil for bacteria gardens Boil some rice or potatoes in a dish unless well cooked. Drain and save the water. Use the bouillon cube to the gelatin. Use th

Osseointegration in immediate placement of implants, Q. Osseointegration In...

Q. Osseointegration In Immediate Placement Of Implants? In routine procedures, delayed placement of implants is done. However, immediate placement of implants into fresh extrac

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd