Chronic bronchitis, Biology

Assignment Help:

Chronic Bronchitis

Chronic Bronchitis is defined clinically as hypersecretion of mucus and recurrent episode of productive cough for a period of 3 months per year at least two consecutive years. 

Pathophysiology

First there is glandular hypertrophy. Mucous gland hypertrophy and hyperplasia from chronic irritations cause excessive mucus production. The excessive mucus and impaired ciliary movement associated with chronic bronchitis increase susceptibility to infection. As infection progress, the epithelial cells produce a mucopurulent exudates in the lumen or the disease may progress to ulceration and destruction of the bronchial wall. The peribronchial fibrosis and the presence of granulation tissue result in stenosis and airway obstruction.

Second the bronchial wall tissue changes, mucosal ocdema and excessive mucus production, all increase airway resistance in persons with chronic bronchitis. Excess mucus may also cause bronchospasm. 

Third the pathophysiologic changes may impair the ability of lungs to exchange 0, and CO, leading to ventilation-perfusion mismatching at the alveolar-capillary membrane. Obstructed airways may lead to atelectasis which further diminishes the surface are a available for respiration. Fourth the right ventricular decompensation or corpulmonale may result.


Related Discussions:- Chronic bronchitis

Define key concepts and facts on properties of monosaccharid, Define Key Co...

Define Key Concepts and Facts on Properties of Monosaccharides? 1. All monosaccharides are soluble in water. 2. All monosaccharides give Molisch's test. 3. Monosaccharides do n

Define vaccine immunogenicity, Immunogenicity Based on immunogenicity s...

Immunogenicity Based on immunogenicity studies and experience with other vaccines, the new meningococcal conjugate vaccine (Menactra) should be highly effective in preventing m

For the biological diversity is mitosis or meiosis, For the biological dive...

For the biological diversity is mitosis or meiosis the more important process? Meiosis is the cell division process that permits the formation of gametes to sexual reproduction

Properties of pyridoxine, Properties of pyridoxine a)  It forms white, ...

Properties of pyridoxine a)  It forms white, odourless  crystals. b)  The compound is readily soluble  in water. c)  When  a neutral or alkaline solution of pyridoxine is

Which technique would use to see if a particular protein, Which technique w...

Which technique would you use to A) see if a particular protein bound to a piece of DNA B) Detect exactly where on a piece of DNA a protein bound.

Wet and dry thermal treatment, Wet and dry thermal treatment Wet therma...

Wet and dry thermal treatment Wet thermal treatment: it is based on exposure of shredded infectious waste to high temperature, high pressure steam. It is inappropriate for the

Metabolism of proteins, The major component of food is protein. The protein...

The major component of food is protein. The proteins ingested as part of our diet are not the same proteins required by the body, nor can large molecules be absorbed from the gut.

Nutrition, prove oxygen is produced during photosynthesis in the presence o...

prove oxygen is produced during photosynthesis in the presence of light

What is megalobastic anemia, Question 1) What is megalobastic anemia? Disc...

Question 1) What is megalobastic anemia? Discuss briefly its lab diagnosis. How would you differentiate megaloblastic anemia from other anemias? Question 2) What is hem

List the benefits of lsm, List the benefits of LSM. Life style modifica...

List the benefits of LSM. Life style modification helps in the following ways: - Reduction of weight - Good sugar control - Good blood pressure control - Reduction

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd