Chronic bronchitis, Biology

Assignment Help:

Chronic Bronchitis

Chronic Bronchitis is defined clinically as hypersecretion of mucus and recurrent episode of productive cough for a period of 3 months per year at least two consecutive years. 

Pathophysiology

First there is glandular hypertrophy. Mucous gland hypertrophy and hyperplasia from chronic irritations cause excessive mucus production. The excessive mucus and impaired ciliary movement associated with chronic bronchitis increase susceptibility to infection. As infection progress, the epithelial cells produce a mucopurulent exudates in the lumen or the disease may progress to ulceration and destruction of the bronchial wall. The peribronchial fibrosis and the presence of granulation tissue result in stenosis and airway obstruction.

Second the bronchial wall tissue changes, mucosal ocdema and excessive mucus production, all increase airway resistance in persons with chronic bronchitis. Excess mucus may also cause bronchospasm. 

Third the pathophysiologic changes may impair the ability of lungs to exchange 0, and CO, leading to ventilation-perfusion mismatching at the alveolar-capillary membrane. Obstructed airways may lead to atelectasis which further diminishes the surface are a available for respiration. Fourth the right ventricular decompensation or corpulmonale may result.


Related Discussions:- Chronic bronchitis

Nutrition support for myocardial infarction, Q. Nutrition Support for myoca...

Q. Nutrition Support for myocardial infarction patient? The nutrient requirements of a MI patient vary from time of getting hospitalized in an emergency to the time of getting

Muscles, what process provides the energy for muscle contraction?

what process provides the energy for muscle contraction?

Peak flow velocity, Peak Flow Velocity  fs  derived  from Doppler  shift by...

Peak Flow Velocity  fs  derived  from Doppler  shift by  rearranging Doppler equation: V = C/2 x ΔF/Fo Various  information can be obtained from spectral display

What is procambium, What is Procambium? The procambium produces cells...

What is Procambium? The procambium produces cells that eventually become the vascular tissues xylem and phloem. These primary vascular tissues form a core in the center of th

Extraradicular infections, Extraradicular Infections Whatever the cause...

Extraradicular Infections Whatever the cause of post endodontic disease we should do proper diagnosis to determine what is the cause; is it intra or extraradicular infection ,

Obelia, why is obelia considered to of special interest in Zoology as an an...

why is obelia considered to of special interest in Zoology as an animal showing an intermediate grade of organisation?

Asexual reproduction - its prevalence and significance, Asexual Reproductio...

Asexual Reproduction - Its Prevalence and Significance Having studied the several aspects of asexual reproduction in the non-chordates we can now make a few generalizations.

Magnitude of healthcare expenditure, Normal 0 false false f...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Explain supravalvular aortic stenosis murmur, Explain Supravalvular aortic ...

Explain Supravalvular aortic stenosis murmur? Supravalvular Aortic Stenosis Murmur : Characteristic: Murmur may be loudest in 1st Right ICS. It isn't associated with systolic

Pre-embryonic development, Pre-Embryonic Development We had said in t...

Pre-Embryonic Development We had said in the starting of the unit that prenatal development can be divided into two phases, embryonic and foetal. The embryonic phase of devel

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd