Chronic bronchitis, Biology

Assignment Help:

Chronic Bronchitis

Chronic Bronchitis is defined clinically as hypersecretion of mucus and recurrent episode of productive cough for a period of 3 months per year at least two consecutive years. 

Pathophysiology

First there is glandular hypertrophy. Mucous gland hypertrophy and hyperplasia from chronic irritations cause excessive mucus production. The excessive mucus and impaired ciliary movement associated with chronic bronchitis increase susceptibility to infection. As infection progress, the epithelial cells produce a mucopurulent exudates in the lumen or the disease may progress to ulceration and destruction of the bronchial wall. The peribronchial fibrosis and the presence of granulation tissue result in stenosis and airway obstruction.

Second the bronchial wall tissue changes, mucosal ocdema and excessive mucus production, all increase airway resistance in persons with chronic bronchitis. Excess mucus may also cause bronchospasm. 

Third the pathophysiologic changes may impair the ability of lungs to exchange 0, and CO, leading to ventilation-perfusion mismatching at the alveolar-capillary membrane. Obstructed airways may lead to atelectasis which further diminishes the surface are a available for respiration. Fourth the right ventricular decompensation or corpulmonale may result.


Related Discussions:- Chronic bronchitis

using a two-sample t-test , After stinging its victim, the honeybee leaves...

After stinging its victim, the honeybee leaves behind the barbed stinger, poison sac, and muscles that continue to pump venom into the wound. A study compared two methods of removi

When aerobic cells carry out fermentation, Under which conditions do aerobi...

Under which conditions do aerobic cells carry out fermentation? Some cells that as a rule get energy from aerobic cellular respiration can carry out fermentation when oxygen is

The similarities and differences of transposable elements, Discuss the simi...

Discuss the similarities and differences of transposable elements in E. coli, yeast, plants, and Drosophila.

Explain about the spinal trauma, Explain about the Spinal Trauma? Spina...

Explain about the Spinal Trauma? Spinal trauma or spinal cord injury, commonly clue to accidents, fills, sports injury can result in serious disabling consequences. The spinal

Limerick, how do we write a limerick spell?

how do we write a limerick spell?

Physical properties of protoplasm, What is the physical experiment that sho...

What is the physical experiment that show that the protoplasm has contractility?

Explain procedure for test of presence of coliform bacteria, Explain Proced...

Explain Procedure for the test of Presence of Coliform Bacteria? This test procedure is in continuation to the presumptive test procedure followed on last experiment. Now carry

Parthenogenesis- asexual reproduction, Normal 0 false false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

What is the morphological feature of molluscs, Q What is the morphological ...

Q What is the morphological feature of molluscs after which the phylum is named? The word "mollusc" imply "soft thing". Molluscs have soft bodies and this feature describes the

Characteristics of river systems, Characteristics of River Systems Th...

Characteristics of River Systems The basic function of the rivers is to convey surplus rain water from land to sea. Annually the rivers carry fresh water, equivalent to 25 cm

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd