Chronic bronchitis, Biology

Assignment Help:

Chronic Bronchitis

Chronic Bronchitis is defined clinically as hypersecretion of mucus and recurrent episode of productive cough for a period of 3 months per year at least two consecutive years. 

Pathophysiology

First there is glandular hypertrophy. Mucous gland hypertrophy and hyperplasia from chronic irritations cause excessive mucus production. The excessive mucus and impaired ciliary movement associated with chronic bronchitis increase susceptibility to infection. As infection progress, the epithelial cells produce a mucopurulent exudates in the lumen or the disease may progress to ulceration and destruction of the bronchial wall. The peribronchial fibrosis and the presence of granulation tissue result in stenosis and airway obstruction.

Second the bronchial wall tissue changes, mucosal ocdema and excessive mucus production, all increase airway resistance in persons with chronic bronchitis. Excess mucus may also cause bronchospasm. 

Third the pathophysiologic changes may impair the ability of lungs to exchange 0, and CO, leading to ventilation-perfusion mismatching at the alveolar-capillary membrane. Obstructed airways may lead to atelectasis which further diminishes the surface are a available for respiration. Fourth the right ventricular decompensation or corpulmonale may result.


Related Discussions:- Chronic bronchitis

Determine fat-soluble vitamins recommended for infant, Determine fat-solubl...

Determine fat-soluble vitamins Recommended for Infant? ICMR (1990) does not give recommendations for vitamins D, E and K. As you already know, vitamin D is expected to be met

Respiratry system, prepare a power point presantation of respiratry system

prepare a power point presantation of respiratry system

Examine the blood types, Discuss blood types, the factors in crime scenes. ...

Discuss blood types, the factors in crime scenes. What is a criminal case where blood samples were important in the case decision and outcome, what was it about the blood in this c

Explain the role in insulin formation, Explain the Role in Insulin Formatio...

Explain the Role in Insulin Formation? You are aware that insulin receptors are present in many cells with their concentration being highest in adipocytes (cells present in adi

Elaborate the internal vascular circulation of an eye, Elaborate the intern...

Elaborate the internal vascular circulation of an eye. Retinal vessels are derived from central retinal artery and are distributed within the inner two-third of retina. Outer o

What progeny are expected in the f1, Cut wings (ct) is an X chromosome (sex...

Cut wings (ct) is an X chromosome (sex linked) recessive mutant of D melanogaster. Antennaless (al) is an autosomal recessive mutant. A cut, antennaless (homozygous) female is mate

Metazoans., explain the different types of symmetry in metazoans.

explain the different types of symmetry in metazoans.

Differenciate b/w gymnosperms -pteridophytes- bryophytes, How different are...

How different are gymnosperms from pteridophytes and bryophytes? Gymnosperms are not cryptogamic as pteridophytes and bryophytes are. They are phanerogamic and so they form see

Define nutritional support management for pancreatic cancer, Define Nutriti...

Define Nutritional Support Management for pancreatic cancer? When there is deficiency of exocrine pancreatic secretions, adequate amounts of pancreatic extract are helpful. It

Define the chemical fixation method, Define the Chemical Fixation Method? ...

Define the Chemical Fixation Method? Here chemical fixatives containing ethanol, acetic acid and formaldehyde etc. penetrates the cell and inactivates and immobilizes cellular

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd