Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Cell, what is cell and what are the components of cell

what is cell and what are the components of cell

Myocardial protection-open heart surgery, Myocardial Protection :  To a gr...

Myocardial Protection :  To a great extent, the result of cardiac surgery depends on how well the myocardium is protected during cardio pulmonary bypass. Temporary depression of m

Cleavage and gastrulation, Cleavage and Gastrulation Eventually, one s...

Cleavage and Gastrulation Eventually, one spermatozoon fuses with the ovum to r restore the diploid genomic condition and activates all the potentials in the fertilized egg ce

Define development - terminologies used in chromatography, Define Developme...

Define Development - Terminologies used in Chromatography? Development is the process of passing a mobile phase over the adsorbent or support. During the development the sample

Metastasis - characteristics define cancer, Metastasis - Characteristics De...

Metastasis - Characteristics Define Cancer Metastasis is the capability of a malignant cell to detach itself from a tumor and establish a tumor in another site. This capabilit

Genetics, Ask question importance of genetics in human life #Minimum 100 w...

Ask question importance of genetics in human life #Minimum 100 words accepted#

How body size and composition affecting the bmr, How Body size and composit...

How Body size and composition affecting the BMR? Basal and resting energy expenditures are related to body size, being most closely correlated with the size of the fat-free mas

What is self-jamming, What is Self-jamming Unless all of the mobile cli...

What is Self-jamming Unless all of the mobile client are perfectly synchronized, the arriving transmissions from multiple clients will not be perfectly aligned on chip boundari

Chromosomes and their organization, Chromosomes   and Their Organization ...

Chromosomes   and Their Organization During  division  phase , the duplicated  chromatin  fibres  become extremely  shortened (= condensed),  by coiling and folding ,into short

Develop questions which will facilitate effective research, Theories are im...

Theories are import because they can be used to a. Test research hypothesis b. Develop questions which will facilitate more effective research c. Conduct more meaningful and useful

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd