Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Discuss about dengue and aids, Why is it difficult to produce efficient vac...

Why is it difficult to produce efficient vaccines against a viral infection like dengue and AIDS? It is complex to make vaccines against dengue because there are four dissimila

What is the symptoms of vibrio parahaemolyticus, what is the Symptoms of VI...

what is the Symptoms of VIBRIO PARAHAEMOLYTICUS Symptoms: A total of greater than one million organisms may cause disease.  Symptoms of intoxication which range from mild to se

Explain about genetic diversity, Q. Explain about Genetic Diversity? Ge...

Q. Explain about Genetic Diversity? Genetic diversity is the "fundamental currency of diversity" that is responsible for variation. This is the diversity of basic units of here

Define the symptoms of dry beriberi, Define the Symptoms of Dry beriberi? ...

Define the Symptoms of Dry beriberi? Early symptoms are similar to those found in wet beriberi. The muscles become progressively wasted and weak and walking becomes difficult.

Define the bacillus cereus, Define the Bacillus cereus Bacillus cereus ...

Define the Bacillus cereus Bacillus cereus is not a common cause of food poisoning. It is a Gram positive, aerobic, spore forming rod shaped bacteria normally present in soil,

Theory of embryology - baer''s law, BAER' S LAW - It was given by K.E....

BAER' S LAW - It was given by K.E. Von Baer. Von Baer was the first scientist who studied the embryology systematically. According to it, in the embryonic development of an

An a=t mispairing leads to an a=c substitution, An A=T mispairing leads to ...

An A=T mispairing leads to an A=C substitution. The other DNA helix will contain a(n) __ pair. a. A=C b. A=T c. G=C d. B=Q e. T=T Can you also explain it please so if I'm ask

Explain amylopectin, Amylopectin Amylopectin forms a branched structure...

Amylopectin Amylopectin forms a branched structure with about 30 glucose units in a chain among branches. There are usually slightly more  'outer' unbranched chains (called A-c

Differance between rescue-capacity-building strategy, QUESTIONS: Write ...

QUESTIONS: Write an analysis of the Chapter Twelve, the concluding chapter in ROLL AWAY THE STONE. It will be worth UP TO 50 points if you do it well. Submit it through the "Ex

Bacteriophage, Bacteriophage is a virus which infects a bacterium and whic...

Bacteriophage is a virus which infects a bacterium and which is many times used in molecular genetics experiments as the vector, or cloning vehicle. Recombinant phages can be made

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd