Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Morphogenetic processes, Morphogenetic Processes We discussed earlier...

Morphogenetic Processes We discussed earlier the process through which a fertilized egg assumes the shape of a ball or a sheet of cells around a cavity, called blastula. Cons

Explain the amphibian heart and the reptile heart, What is the difference b...

What is the difference between the amphibian heart and the reptile heart? The reptiles have double and incomplete circulation too, three heart chambers (two atria and one ventr

What do you mean by tympanum, Q. What is the tympanum? In which part of the...

Q. What is the tympanum? In which part of the ear is it located and what is its function? The tympanum (or ear drum) is a membrane located in the middle ear just after the audi

To induce the formation of a complete plant, In the process of tissue cultu...

In the process of tissue culture in plants, what is required to induce the formation of a complete plant, in addition to a growth medium with nutrients?   The appropriate p

Define higher order structure, Which kind of weak interaction can define hi...

Which kind of weak interaction can define higher order structure and in the same time DNA.

Define nutrition management and feeding the premature infant, Define Nutrit...

Define Nutrition Management and Feeding the Premature Infant There are numerous nutritional risk factors in premature infants. These include: Elevated metabolic rate, th

How is digestion performed in protozoans, How is digestion performed in pro...

How is digestion performed in protozoans? Digestion in protozoans is intracellular digestion: organic material is internalized and degraded inside the cell. Protozoans get

Name the process in that substances carry across membrane, Substances which...

Substances which are insoluble in a membrane are carried across membrane with concentration gradient by means of a carrier molecule in a process termed as: a) Diffusion. b)

What are some examples of phenotypical, What are some examples of phenotypi...

What are some examples of phenotypical characteristics that present two or more varieties and of phenotypical features that do not vary? In relation to the genes correspondent to t

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd