Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Explain about the simple proteins, Explain about the Simple Proteins? S...

Explain about the Simple Proteins? Simple proteins are those that are made of amino acid units just joined by peptide bond. Upon hydrolysis they yield a mixture of amino acids

Describe how many bones are there in human foot, Describe how many bones ar...

Describe how many bones are there in human foot The human foot is a great mechanical marvel. It has 26 bones, 29 joints, and 42, various ligaments, a sensitive and protective s

Improvement of soil aeration-aggregate structure, Improvement of Soil Aerat...

Improvement of Soil Aeration Soil organisms greatly improve soil structure and facilitate aeration. Root decay leaves the soil riddled with channels, and the burrowing of worm

Define objectives to know about methods of food processing, Define Objectiv...

Define Objectives to know about methods of food processing? After studying this unit, you will be able to: Enumerate the different methods of food processing Enlist

How physical activity affect requirement of protein, How Physical Activity ...

How Physical Activity affect requirement of protein? Research on protein needs for muscular work had its beginning in 1863 when Von Leiberg postulated that muscle protein was d

Coadapted communities, From your studies in ecology, you must be aware that...

From your studies in ecology, you must be aware that most ecosystems are quite complex consisting of several habitats and that habitats in turn are composed of microhabitats. Each

Illustrate steps of polymerase chain reaction , There are three steps of PC...

There are three steps of PCR a) Denaturation.  The reaction combination is heated to 95°C for a short time period (about 15-30 sec) to denature the goal DNA into one strands w

Community change, Community Change Ecosystems are dynamic entities in ...

Community Change Ecosystems are dynamic entities in which a number of events take place. Associated with the biotic communities of the ecosystem are some changes, which may be

Define main gastric digestive enzyme, Q. Besides being fundamental for the ...

Q. Besides being fundamental for the activation of the main gastric digestive enzyme how does HCl also directly participate in digestion? With its corrosive effect HCl also hel

Kjlkjkp, Ask quesouou9ution #Minimum 100 words accepted#

Ask quesouou9ution #Minimum 100 words accepted#

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd