Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Digestive system in the phylum arthropoda, Q. What is the kind of digestive...

Q. What is the kind of digestive system present in beings of the phylum Arthropoda? Are these animals deuterostomes or protostomes? The digestive tube of arthropods is complete

Radiographic evaluation - criteria for endosteal implants, Radiographic Eva...

Radiographic Evaluation - criteria for endosteal implants Surgical and interventional imaging involves imaging the patient  during and immediately after surgery and during the

State the list of behavioural observations, State the list of Behavioural O...

State the list of Behavioural Observations A typical list of domains would include the following: Mood and affect Motivation and cooperation Social interaction

Explain the radiographic success of root canal treatment, Explain the Radio...

Explain the Radiographic Success of Root Canal Treatment Elimination or lack of development of an area of rarefaction (= Radiolocency )  for a minimum of I year after treatment

Describe imz implant system, Q. Describe IMZ Implant System? Then came ...

Q. Describe IMZ Implant System? Then came the IMZ Implant System (Interpore IMZ) in 1974. The major difference between the IMZ System and all other relevant implant systems is

Explain about pentoses, What are pentoses? To what organic group do pentose...

What are pentoses? To what organic group do pentoses belong? Are nucleotides formed of only one type of pentose? Pentoses are carbohydrates made of five carbons. Deoxyribose is

Determine the general principles for incisions, General Principles for Inci...

General Principles for Incisions The general principles for placing incisions so as to create surgical flaps remain the same regardless of the reason for creating them. These a

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd