Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

What are the factors to an actual shift in the demand curve, What are the f...

What are the factors to an actual shift in the demand curve? Factors that cause an actual shift within the demand curve are as follows: When prices rise or fall that would c

Structures in the Dermis, list of the structures you would expect to find i...

list of the structures you would expect to find in the dermis.

How does water move inside sponges, How does water move inside sponges? Wha...

How does water move inside sponges? What is the function of the pores in these animals? Sponges are filtering beings. They make water enter their bodies by their lateral pores

List four common exercises you will recommend to a patient, List four commo...

List four common exercises you will recommend to a patient. Common exercises are: - brisk walking - cycling - swimming - playing tennis - dancing - rope skip

Which part of heart serves as an actuating signal, Which of the following s...

Which of the following serves as an actuating signal, or as part of an actuating signal, in a negative feedback system? A. Action potentials in sympathetic neurons that release

Which compounds results from cyclization of glucose, Which of the following...

Which of the following compounds results from cyclization of glucose? Select one: a. alpha-D-glucopyronose b. beta-D-glucopyronose c. alpha-D-glucofuranose d. beta-D

Which of these lists contains the four postulates, Which of these lists con...

Which of these lists contains the four postulates  of natural selection? Which of these lists contains the four postulates of natural selection? Uniform population, heritable trait

What is the main cell organelle involved in cell digestion, What is the mai...

What is the main cell organelle involved in cell digestion? What are the properties of that organelle that enable it to do the task? The organelles responsible for intracellula

Explain the integumentary system in human biology, Explain the Integumentar...

Explain the Integumentary System in human biology? The skin, its glands, and outgrowths form the Integumentary system. This system provides protection, sensory perception, tem

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd