Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Find the genotypes and phenotypes of the f1, Determine the genotypes and ph...

Determine the genotypes and phenotypes of the F1 generation from a colour blind father and a mother who is homozygous for normal colour vision.

Describe the role of vntrs in linkage analysis, Question 1: Show applic...

Question 1: Show applications of Bioinformatics in pharmacogenomics. Expand FASTA and BLAST. List out any 10 applications of Bioinformatics in pharmacogenomics Expand

Diffusion, applications of diffusion

applications of diffusion

What is the clitellum of earthtworms, Q. What is the clitellum of earthtwor...

Q. What is the clitellum of earthtworms and where it is located? The clitellum is a special region of the annelid constituted by rings (metameres) with reproductive function. I

Mosaic and regulative eggs, Mosaic and Regulative Eggs Eggs as well a...

Mosaic and Regulative Eggs Eggs as well as early cleavage embryos are occasionally divided into two categories: i) Mosaic or determinate embryos and ii) Regulative or i

Define the nutrient requirements during trauma, Define the Nutrient Require...

Define the Nutrient Requirements during Trauma? Nutritional assessment of the trauma patient is done to determine energy and protein requirements. Basal energy requirements are

Explain keshan disease caused by selenium deficiency, Explain Keshan diseas...

Explain Keshan disease caused by Selenium deficiency? It is a cardiomyopathy (disease of the myocardium, involving heart muscle) that was identified to affect children and wome

St-segment depression after hyperventilation, Q. ST-segment depression aft...

Q. ST-segment depression after  hyperventilation? Patients with abnormal autonomic drive have demonstrated ST-segment depression after hyperventilation as well as after exercis

What concentration of sucrose solution should administered, The volume of M...

The volume of Mrs. X's plasma was 3 liters before Ed administered the IV. Assume that there was a complete mixing of the administered water with her plasma but no mixing with her i

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd