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Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain (1) fragments further from the required gene (which are discarded); (2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or (3) fragments from within required gene - the optimal result.
DRUG DEPENDENCE - Some drugs are prescribed by doctor for the prevention or treatment of a disease. Some drugs are used for long periods. A person becomes addict to these
Role of exercise in the management of diabetes mellitus Exercise is another important component of life style modification. Like diet control, regular exercise is important in
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Q. Treatment of diabetic ketoacidosis? The components of treatment of NKHDC are: 1) control of water loss. 2) control of sugar using insulin. 3) adjust electrolytes li
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Describe what happens during activation of the lac operon. Lactose binds to the repressor protein, which causes the repressor protein to be released from the operator site. Th
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Explain about enzymes All enzymes are proteins. Many enzyme proteins lack catalytic activity in the absence of a non-protein component, called a 'co-factor'. In this case, the
Q. What are the major events of the first mitotic period? The first mitotic period is the prophase. During prophase the following events occur migration of each centriole pair
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