Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Illustrate the name of surgical needle, Illustrate the name of surgical ne...

Illustrate the name of surgical needle The surgical needle is comprised of 3 parts: the needle point, the needle body, and the swaged (press-fit) end. Needle may be broadl

What happen when the standard free energy of a reaction, When the standard ...

When the standard free energy of a reaction is -5.7 kj/mol then at equilibrium a- there will be 10 times more products than reactants b-there will be 10000 times more product

What happens within the cell in the third interface period, What are the ev...

What are the events that mark the beginning and the end of the third interphase period? What happens in the cell in this period? The third interphase period is the G2. It star

Describe the theory of darwins, Describe the theory of Darwin's? Most s...

Describe the theory of Darwin's? Most scientists today accept the theory that living organisms have evolved according to the concept that was first proposed by Charles Darwin i

Salivary analyse works on foods, Explain how salivary amylase works on food...

Explain how salivary amylase works on foods like crackers

Agro industrial-incriminating factors in feeds, Agro Industrial-Incriminati...

Agro Industrial-Incriminating factors in feeds There are many anti-nutritional factors present in feeds and fodders which affect the utilization of nutrients. Some of these are

Define tests to measure muscular strength and endurance, Define Tests to Me...

Define Tests to Measure Muscular Strength and Endurance? It is important to first understand the difference between muscular strength and endurance. To know the muscular streng

Explain the mechanical requirements of implant materials, Mechanical requir...

Mechanical requirements of implant materials Dental implant s must be able to sustain and transfer loads -It should have adequate mechanical strength in order to distribute th

How can the reactions of the nervous system be classified, Q. Concerning vo...

Q. Concerning volition of the individual how can the reactions of the nervous system be classified? The efferences (reactions) of the nervous system can be classified into volu

Explain about the serum vitamin b12 assay, Explain about the Serum vitamin ...

Explain about the Serum vitamin B12 assay? Serum vitamin B 12 assay: The vitamin B 12 content of serum can be determined.  A serum level of 12 deficiency.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd