Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

What happens to denatured enzyme regarding it functionality, What happens t...

What happens to a denatured enzyme regarding its functionality? How can that result be explained with the help of the lock and key model? According to the lock and key model th

Super cooling - temperature relations in animals, Normal 0 fals...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Theories of origin of life, what we the strengths and weaknesses of pangene...

what we the strengths and weaknesses of pangenesis theory

Cryo preserved allografts -surgical techniques, Cry o Preserved Allograf...

Cry o Preserved Allografts (Homograft) :  As these are not mounted, a free hand suturing in two layers has to be done. The valve is thawed by protocol. The septal muscle i

Hyperthyroidism (graves disease), Hyperthyroidism (Graves Disease): Gr...

Hyperthyroidism (Graves Disease): Graves diseases is  the most common cause of hyperthyroidism  in  children and is usually associated with an  enlarged thyroid gland and exop

What is the futile cycle, What is the futile cycle The futile cycle is ...

What is the futile cycle The futile cycle is avoided because covalent modification, by  phosphorylation, has opposite effects on  the  enzymes concerned with  the  synthesis  a

Lower invertebrates, adaptation of the phylum protozoa to its function

adaptation of the phylum protozoa to its function

What is the ranges of tolerance and performance optima, What is the ranges ...

What is the ranges of tolerance and performance optima? Ranges of Tolerance and Performance Optima :   When it comes to physical factors or resources, most species are able to

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd