Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Explain biological aspects of nutrition, Explain biological aspects of nutr...

Explain biological aspects of nutrition Traditionally nutritionists have focused largely (or almost fully) on . However, we have realized over the years, that physiological bio

How does the contraceptive diaphragm work, Q. How does the contraceptive di...

Q. How does the contraceptive diaphragm work? What are the limitations of this contraceptive method? The contraceptive diaphragm is an artifact made of plastic or latex that wh

Types of synovial joint, TYPES OF SYNOVIAL JOINT - 1 .      BALL AND ...

TYPES OF SYNOVIAL JOINT - 1 .      BALL AND SOCKET JOINT - One bone forms a ball like head that fits into a socket formed in the other bone. Movement is possible in al

Show water permeability of the luminal membranes, Healthy Person H takes a ...

Healthy Person H takes a new drug named ANTICAMPCOLLDUCT that blocks the production of cyclic AMP (cAMP) in collecting duct epithelial cells in response to vasopressin binding to V

Management of chest injury, Management Establish and maintain airwa...

Management Establish and maintain airway. Anticipate need for incubation if respiratory distress evident.  Administer high humidified O 2 , using non-rebreather mask.

Pethidine and methadone, PETHIDIN E - Meperidine hydrochloride. ...

PETHIDIN E - Meperidine hydrochloride. Widely used as narcotic analgesic. It has local anesthetic action. METHADON E - It is an orally effective anal

Angiosperms, why are the microspores in groups of four?

why are the microspores in groups of four?

Levels of organization of matter - metazoa, Levels of organization of Matte...

Levels of organization of Matter- Metazoa The smallest structural units of all matter are subatomic particles, mainly electrons, protons and neutrons. The next larger units a

Pulmonary ventilation, Pulmonary Ventilation: Pulmonary ventilation is th...

Pulmonary Ventilation: Pulmonary ventilation is the process by which gasses flow between the atmosphere and lung alveoli. Air moves into the  lungs when air pressure  inside the

Define barrier layer cells (photocells), Define Barrier layer cells (photoc...

Define Barrier layer cells (photocells) They are the very simple of the detectors. It contains the bottom support layer of conductive metal like iron. A photosensitive layer of

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd