Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Biological fixation - nitrogen fixation, Biological fixation - Nitrogen Fix...

Biological fixation - Nitrogen Fixation Approximately 63% of all nitrogen fixed is through biological fixation. Nitrogen fixing organisms are primarily prokaryotes; bacteria a

How much calories in dried fruits, How much calories in Dried fruits Dr...

How much calories in Dried fruits Dried fruits are exceptionally rich in calories and they supply significant amounts of minerals. Of the vitamins found in fruits, β-Carotene a

What is life threatening haemorrhage, What is Life threatening haemorrhage ...

What is Life threatening haemorrhage Life threatening haemorrhage has been reported when a drill perforates the sublingual region of the mandible and injures the sublingual arte

Zoology, main external morphological feature that differentiates platyhelmi...

main external morphological feature that differentiates platyhelminthes from nematodes

Explain process of glycosylation, Glycosylation: The covalent addition of ...

Glycosylation: The covalent addition of the sugar moities to N or O atoms present in the side chains of various amino acids of certain proteins, usually occuring within the Golgi

Define pipette - nutritional biochemistry, Define Pipette - Nutritional Bio...

Define Pipette - Nutritional Biochemistry? Pipettes are used to deliver a known volume of liquid from one container to another. They are precision instruments of measurement an

Define economically important fermentation products, Normal 0 f...

Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4

Define regulation of intracellular ca concentration, Define Regulation of i...

Define Regulation of intracellular Ca concentration? The cytoplasmic calcium concentration is regulated by a series of calcium pumps, which either concentrate calcium ions with

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd