Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Define effect of antioxidants on athletes, Define effect of Antioxidants on...

Define effect of Antioxidants on athletes? Antioxidants like ascorbic acid (vitamin C), tocopherols (vitamin E), selenium, glutathione (GSH) Supplementation (singly or in combi

Growth charts, Growth Charts Management alone without any standard of ...

Growth Charts Management alone without any standard of comparison do not serve useful purpose. A number of standards have been developed to compare the measurement of any

minerals, Minerals Minerals are chemical elements needed by the body ei...

Minerals Minerals are chemical elements needed by the body either to help form bodily structures or to facilitate chemical reactions. Dietary minerals are divided into two categ

What is aortic stenosis, Q. What is Aortic stenosis? Left Ventricular o...

Q. What is Aortic stenosis? Left Ventricular outflow tract obstruction can occur due to various aortic valvular, subvalvular and supra valvular lesions. Valvular Aortic Ste

What is lymphatic system in human biology, What is Lymphatic System in huma...

What is Lymphatic System in human biology? The lymphatic system maintains fluid balance and serves in protecting the body from disease. The primary organs of the lymphatic syst

Proteins of plant origin - vegetable proteins, Proteins of Plant Origin ...

Proteins of Plant Origin Vegetable Proteins: Fresh vegetables are not considered to be a very good source of proteins. On fresh weight basis, the average protein content of s

Explain numeric pyramid base to be smaller than other level, In a numeric p...

In a numeric pyramid is it possible for the base to be smaller than the other levels? Ever since the numeric pyramid represents the quantity of individuals in each trophic leve

What are the main negative ions found in living beings, What are the main n...

What are the main negative ions found in living beings? The major anions found in living beings are the chlorine anion (Cl-), the phosphate anion (PO4--), the bicarbonate anion

Derive gorlin formula, Q. Derive Gorlin Formula? Formula I: First Hydra...

Q. Derive Gorlin Formula? Formula I: First Hydraulic Formula (Toricelli's law) F = AVCc Where, F = flow rate A = orifice area Cc = coefficient of orifice cont

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd