Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Photosynthesis, why is a potted plant destarched before starting the experi...

why is a potted plant destarched before starting the experiment to investigate the factors necessary for photosynthesis

Diagnostic evaluation of leukemia, Diagnostic Evaluation   A  study of ...

Diagnostic Evaluation   A  study of complete blood count (CBC) and blood chemistry mainly uric acid levels, is necessary for dignostic evaluation.  Radiologic  studies  are

Define adsorption chromatography -basic separation technique, Define Adsorp...

Define Adsorption chromatography - Basic Separation Technique? Adsorption is surface interaction and is by number of forces, between surface atoms of solids and molecules of ex

Respiration, comparitive chart on different types of respiration obserbed i...

comparitive chart on different types of respiration obserbed in different type of respiration organ of respiration , types of respiration,energy obtained , by product formed

Explain pasteurization - method of food preservation, Explain Pasteurizatio...

Explain Pasteurization (temperature below 100° C) - method of food preservation? Pasteurization is a heat treatment that kills a part but not all the microorganisms present and

Central cell - synergids, Central Cell - Synergids It is the largest c...

Central Cell - Synergids It is the largest cell of the embryo sac, and the mother cell of the endosperm. The enlargement of the embryo sac after the last nuclear division is m

Give the details of colour vision, Give the Details of Colour Vision Th...

Give the Details of Colour Vision The genes for colour sense are located on the X chromosome (recessive inheritance) and on chromosomes 3 and 7. Changes in the cone pigments as

Calculate the electric potential, The three charges in the are at the verti...

The three charges in the are at the vertices of an isosceles triangle. Let q = 7.00 nC and calculate the electric potential at the midpoint of the base.

Issues to be discussed while counselling a diabetic patient, Q. Issues to b...

Q. Issues to be discussed while counselling a diabetic patient ? Issues to be discussed · Counselling at Diagnosis · Diabetes is Controllable · Counselling for Day

Chronic bronchitis, Chronic Bronchitis Chronic Bronchitis is defined ...

Chronic Bronchitis Chronic Bronchitis is defined clinically as hypersecretion of mucus and recurrent episode of productive cough for a period of 3 months per year at least tw

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd