Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Illustrate the respiratory system, Illustrate the Respiratory System In...

Illustrate the Respiratory System In general, respiration and breathing are understood to be same. But it is not so. Breathing simply means taking in oxygen from air and giving

How arab influence on the development of anatomy, Please on 3 separate para...

Please on 3 separate paragraph a. Examine the contributions of select scientists from the Greek and Roman period. b. Explore the Arab influence on the development of anatomy

Determine number of sucrose molecules in the solution, Determine number of ...

Determine number of sucrose molecules in the solution When a solid is dissolved in a volatile solvent the vapour pressure of the solution is less than the vapour pressure of th

Hypocalcaemia, H y po c a l c a e m i a It is also known as ...

H y po c a l c a e m i a It is also known as milk fever or parturient paresis. The disease occurs due to imbalance in input and output of calcium and is characterize

Explain process of stress testing in women, Q. Explain process of Stress Te...

Q. Explain process of Stress Testing in Women? Estrogen has been implicated as a cause of ST depression. For years it seemed that estrogen protect women from coronary artery di

Growth phase -stages in spermatogenesis, Growth Phase -Stages in spermatoge...

Growth Phase -Stages in spermatogenesis Growth phase is characterized by the acquisition of the structural and functional characteristics of distinct sex cells. Also here is a

Classification of living things, Ask question what is classification of liv...

Ask question what is classification of livibg thingsMinimum 100 words accepted#

What are the chemical requirements of implant materials, What are the Chemi...

What are the Chemical requirements of implant materials It must withstand corrosion by body fluids It should not have any direct or indirect negative effects on the surround

What is pulmonary venous congestion ?, Q. What is Pulmonary Venous Congesti...

Q. What is Pulmonary Venous Congestion ? In pulmonary venous hypertension, the earliest change is an increase in calibre of the upper lobe vessels. If the upper lobe veins meas

Extraradicular infections, Extraradicular Infections Whatever the cause...

Extraradicular Infections Whatever the cause of post endodontic disease we should do proper diagnosis to determine what is the cause; is it intra or extraradicular infection ,

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd