Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Is water a polar or a non-polar molecule, Is water a polar or a non-polar m...

Is water a polar or a non-polar molecule? What is the consequence of that characteristic for the function of water as solvent? Water is made of two atoms of hydrogen attached b

Assisting in procedure of biopsy, ASSISTING IN PROCEDURE OF BIOPSY Bio...

ASSISTING IN PROCEDURE OF BIOPSY Biopsies are removal of a small piece of tissue for examination under microscope. Such examinations are called hist to pathological examina

Why is it important for chromosomes to be condensed, Why is it important fo...

Why is it important for chromosomes to be condensed during mitosis and decondensed during interphase? During mitosis the major problem to be solved is the correct separation of

The chance of fertilisation in humans, Explain why the chance of fertilisat...

Explain why the chance of fertilisation in humans is restricted to only a few days each month. Sperms can fertilise an ovum for up to about three days after entering the female

Where in living beings can found mineral salts, Q. Which are mineral salts?...

Q. Which are mineral salts? Where in living beings can found mineral salts? Ans. Mineral salts are simple inorganic substances made of metallic chemical elements, like sodiu

Difference between ribosome and plant virus, Difference between Ribosome an...

Difference between Ribosome and plant virus -   RIBOSOME (RNA + Protein)   PLANT VIRUS (RNA + Protein)   1. Does not mul

Reproduction, what are the methods of seed formation

what are the methods of seed formation

What is the ranges of tolerance and performance optima, What is the ranges ...

What is the ranges of tolerance and performance optima? Ranges of Tolerance and Performance Optima :   When it comes to physical factors or resources, most species are able to

What is the part of the female reproductive system, What is the part of the...

What is the part of the female reproductive system where fecundation occurs? Fecundation generally happens in the Fallopian tubes but it can also take place within the uterus.

Social determinants of health - social exclusion, Social Determinants of He...

Social Determinants of Health - Social Exclusion Given that absolute poverty is a major determinant of ill-health, the resultant social exclusion is ‘psychologically damaging,

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd