Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Describe about the argyll robertson pupil, Describe about the Argyll Robert...

Describe about the Argyll Robertson Pupil (ARP) Argyll Robertson Pupil (ARP) occurs in patients who have tertiary syphilis. There is a "light-near dissociation" because pupils

#titlenergye.., Ask queson #Minimum 100 words accepted#sources of fuel whic...

Ask queson #Minimum 100 words accepted#sources of fuel which do not depend on fossil fuel

Explain the drug effects on absorption of nutrients, Explain the Drug Effec...

Explain the Drug Effects on Absorption of Nutrients? Many drugs can impair, prevent or reduce absorption of nutrients due to: Formation of insoluble complexes: many drugs

Determination of neural ectoderm by induction, Determination of Neural Ecto...

Determination of Neural Ectoderm by Induction Earlier you know that the dorsal mesoderm induces the ectoderm to differentiate into neural tissue. Spemann and his co-workers co

Domestic effluents - causes of water pollution, Domestic Effluents - Causes...

Domestic Effluents - Causes of Water Pollution Liquid waste produced daily in kitchen, bathroom and toilet are discharged directly or through canal, river or any other water b

Substrate-level phosphorylation, There are two distinct methods through tha...

There are two distinct methods through that cells synthesize ATP.  In  oxidative phosphorylation which containing  the electron transport  chain and the generation  of ATP is linke

Class of mollusca - aplacophora, Class of Mollusca - Aplacophora Worm...

Class of Mollusca - Aplacophora Worm-like, no shell, head or excretory organs mantle with chitinous cuticle or scales or spicules mantle cavity posterior. Aplacophorans are a

Explain the process of absorption of fats, Explain the process of Absorptio...

Explain the process of Absorption of Fats? After digestion, only 25% of triglycerides are broken completely to glycerol and fatty acids. Major digestion product is 2-monoacylgl

What are the components of mitral valve apparatus, Q. What are the Componen...

Q. What are the Components of mitral valve apparatus? 1) Annulus: Annulus is a saddle shaped structure with medial and lateral portions forming the basal points and anterior a

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd