Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Which animals make cutaneous respiration, Q. Which animals make cutaneous r...

Q. Which animals make cutaneous respiration? Adult amphibians and Terrestrial annelids make cutaneous respiration in amphibians there is also pulmonary respiration, the thin sk

What type of compound is major metabolic waste of porifera, What type of co...

What type of compound is the major metabolic waste of Porifera? Why is it important for the organism to get rid of this compound?

Define colorimetric method - 2, Define Colorimetric Method - 2, 4 Dinitroph...

Define Colorimetric Method - 2, 4 Dinitrophenylhydrazine Method? We shall use this method in estimating vitamin C in a given sample in the laboratory. Here, let us look at the

Explain tuberculosis, Tuberculosis Tuberculosis is a chronic infectious...

Tuberculosis Tuberculosis is a chronic infectious disease which is caused by a bacterium - Mycobacterium tuberculosis.  It affects the lungs most commonly but call gel localize

Composition-atmosphere, Composition The present day composition of atmo...

Composition The present day composition of atmosphere is the product of a lengthy evolutionary process that began more than four billion years ago. It is composed of a mixture

Define about the food effects on drug metabolism, Define about the Food Eff...

Define about the Food Effects on Drug Metabolism? The general tendency of the process of metabolism is to transform a drug from a lipid- soluble to a more water-soluble compoun

What is the function of the citric acid cycle, What is the function of the ...

What is the function of the citric acid cycle? The hnction ofthe  citric acid cycle can be discussed as  follows. The  intermediates of citric acid cycle are used as  precursor

Scintillation counter, carnt understand its principle and mode of working

carnt understand its principle and mode of working

Natural selection and genetic drift, Tell me which statement belongs to eit...

Tell me which statement belongs to either natural selection, genetic drift, or gene flow Can you tell me if I am correct? -Consistently causes a population to become better adapted

Modification of carbohydrate intake for specific disorder, Define Modificat...

Define Modification of Carbohydrate Intake for Specific Disorder? In our daily diet almost 60-7096' of energy is contributed by carbohydrates. Majority of them are comprised of

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd