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Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain (1) fragments further from the required gene (which are discarded); (2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or (3) fragments from within required gene - the optimal result.
Define Precipitation or Solubility of Proteins? Most of the functional properties are dependent on the degree to which the proteins are soluble. The solubility behaviour provid
DEFECT S OF HEART 1 . Blue Baby syndrome (Cyanosis) - Due to persisting foramen ovalis in atrial septum even after birth, the impure blood from right auricles comes to
Define Liposuction - surgical management for obesity? Liposuction is a cosmetic surgical procedure different from bariatric surgery. It involves aspiration of subcutaneous fat
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what is gene?
Define Quantitative or Analytical Method for Estimation of Nitrogen and Protein? You may recall reading earlier that proteins contain nitrogen along with carbon, hydrogen and s
What is the Determination of vitamin B 2 In the chemical method, the yellow-green fluorescence of aqueous solution of riboflavin is measured. In the microbiological assay, tur
In sulfur photosynthetic bacteria what is the molecule that donates hydrogen for photosynthesis? In sulfur photosynthetic bacteria the substance that donates hydrogen is hydrog
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