Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Define autoclave - food microbiology, Define Autoclave - Food Microbiology?...

Define Autoclave - Food Microbiology? For sterilization, steam under pressure is generally employed using an instrument called autoclave. Figure illustrates the autoclave. Auto

Systematics, classification of all organisms under d phylum protozo

classification of all organisms under d phylum protozoa

Explain about the fermentation - methods of food processing, Explain about ...

Explain about the Fermentation - methods of food processing? In contrast to other preservation methods, multiplication of microorganisms and their metabolic activities are enco

1, #phyletic lineage ..

#phyletic lineage ..

Explain hepatitis a and b, Hepatitis A/B  A combination vaccine contain...

Hepatitis A/B  A combination vaccine containing the same antigenic components as  Engerix-B and pediatric  Havrix (Twinrix - GlaxoSmithKline) is available for patients >18 year

Species and habitats, Can you give me an example of the species that crosse...

Can you give me an example of the species that crossed a few habitats?

Target tissues and organs of each adenohypophyseal hormone, Q. What are the...

Q. What are the target tissues and target organs of each adenohypophyseal hormone? GH- bones, muscles and cartilages, Prolactin- mammary glands, ACTH- the cortical portion of t

Define the term parasite -giardia, Normal 0 false false fal...

Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4

Can you illutrate autoimmune diseases, Q. What is the name given to conditi...

Q. What is the name given to conditions in which the own immune system of the individual is the agent of diseases? What are some examples of these conditions? Diseases caused b

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd