Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Define the methods of concentration, Define the Methods of Concentration? ...

Define the Methods of Concentration? We define the concentration process as one that starts with a liquid product and ends up with a more concentrated, although still liquid a

What is kingdom monera, What is Kingdom Monera? The eubacteria, archaeb...

What is Kingdom Monera? The eubacteria, archaebacteria, and blue-green bacteria (or cyanobacteria) which form Kingdom Monera lack the cellular organization that all other livin

Define about the paper chromatography, Define about the Paper Chromatograph...

Define about the Paper Chromatography? Paper chromatography is a very useful technique for separating mixtures of metal ions, anions, amino acids, sugars, dyes, drugs, etc. The

Zoonoses disease-listeriosis, Listeriosis Listeriosis is an important f...

Listeriosis Listeriosis is an important food-borne zoonosis caused by pathogenic species of Listeria. The disease affects both in man and animals. It is a serious invasive dise

Define the term - peroxisomes and glyoxisomes, Peroxisomes and Glyoxisomes ...

Peroxisomes and Glyoxisomes A number of metabolic reactions, such as, the oxidation of amino acids and lipids result in the production of hydrogen peroxide. As hydrogen peroxid

Fructose doesnt have aldehyde group reacts with fehling sol, Although fruct...

Although fructose does not have an aldehyde group it reacts first of all  bonds of fructose was breaked by fehling solution then fructose coverted to aldehydic group then that

Mention the main cause of air pollution in metro cities, a) Mention the mai...

a) Mention the main cause of air pollution in metro cities. Write any three ways by which it can be decreased. b) How did Eli Lilly synthesize the human insulin? Mention

Similarities between cardiac, SIMILARITIE S BETWEEN CARDIAC AND SKELETAL M...

SIMILARITIE S BETWEEN CARDIAC AND SKELETAL MUSCLES - Both cardiac and skeletal muscles are made up of elongated fibres which have numerous myofibrils. The myofibrils of

Races of modern man, RACE S OF MODERN MAN Australoids Negroids ...

RACE S OF MODERN MAN Australoids Negroids Caucasoids Monogoloids American Indian Polynesian All human races have the same number of chromosomes (46) and b

Biosynthesis of cholesterol, Animals are able to synthesize cholesterol de ...

Animals are able to synthesize cholesterol de novo by an elegant series of reactions in that all 27 carbon atoms of cholesterol are derived from acetyl CoA. The  acetate  units  ar

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd