Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Define briefly about the selenium, Define briefly about the Selenium? T...

Define briefly about the Selenium? The element selenium was discovered in 1817 in association with the element sulphur. However, selenium as an essential nutrient remained unre

Indications for emergency surgery in ar, Indications for Emergency Surgery ...

Indications for Emergency Surgery in AR 1) Post balloon valvotomy AR with haemodynamic compromise 2) Acute thrombosis of prosthetic valve, not responding to thrombolysis

Threshold for an action potential in neuron a, Neuron A is a healthy neuron...

Neuron A is a healthy neuron with all the usual ion channels.  When at rest with a membrane voltage of R millivolts, neuron A produces no action potentials.  The voltage thresh

Explain fontan operation and ross operation in heart dieases, Explain fonta...

Explain fontan operation and ross operation in heart dieases? Fontan Operation: The Fontan principle involves redirecting the whole systemic return into the lungs bypassing t

How are the heterotrophic beings divided, How are the heterotrophic beings ...

How are the heterotrophic beings divided in the ecological study of food interactions? The Heterotrophs are divided into consumers and decomposers. An ecosystem can survive wit

Explain the nucleolus, Q. Explain the nucleolus? The nucleolus is an op...

Q. Explain the nucleolus? The nucleolus is an optically and a small dense region in the interior of the cell nucleus. It is made of ribosomic proteins and RNA (rRNA). One nucle

Classification, What is omnispective classification

What is omnispective classification

Cell biology, is the study of internal structure of cell included in cell b...

is the study of internal structure of cell included in cell biology or anatomy?

Why can the genetic code be qualified as a degenerate code, Why can the gen...

Why can the genetic code be qualified as a "degenerate code"? The genetic code is a degenerate code because there are amino acids codified by more than one type of codon. It is

What is herbicide tolerant crops in evolutionary, Evolutionary ...

Evolutionary Herbicide tolerant crops (HTC) Increased use of herbicide can result in increase in development of weed resistance to that herbicide either through

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd