Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

What is rate of photosynthesis in c3 plants, What would happen to the rate ...

What would happen to the rate of photosynthesis in C3 plants if the CO2 concentration level almost doubles from its present level in the atmosphere?

Why iron is required as a part of haemoglobin, Why Iron is required as a pa...

Why Iron is required as a part of haemoglobin? As a part of haemoglobin, iron is required for the transport of oxygen, to all cells in the body. Thus, haemoglobin is critical f

Stored metabolites - seed and fruit, Stored Metabolites - Seed and Fruit ...

Stored Metabolites - Seed and Fruit In a large majority of seeds food is stored in the cells of the endosperm. In coconut, wheat and castor bean for example, it is the endospe

Alkaloids, Miscellaneous antinutritional substances Alkaloids: Alkal...

Miscellaneous antinutritional substances Alkaloids: Alkaloids represent a large and structurally diverse group of compounds present within angiosperm plants; the majority of

What is membrane, Q. What is membrane? Membrane is any delicate sheet t...

Q. What is membrane? Membrane is any delicate sheet that separates one region from another blocking or permitting completely or selectively the passage of substances. The skin,

Excretory system, What are the excretory organ in protozoa,coelenterates, i...

What are the excretory organ in protozoa,coelenterates, insects,spider,and arthropods

fat digestion requires two steps, Fat digestion requires two steps? What a...

Fat digestion requires two steps? What are the steps and what enzymes are used to accomplish each step?

Explain about biodiversity, How do biodiversity, the total number of living...

How do biodiversity, the total number of living beings and the biomass respectively vary during the ecological succession? Biodiversity, the number of living beings and the bio

Why is aids difficult to prevent by vaccination, Q. Why is AIDS difficult t...

Q. Why is AIDS difficult to prevent by vaccination? It is not easy to produce a vaccine against AIDS because the HIV is a highly mutant virus. In approximately every replicatio

Embryology in relation to taxonomy, Q. Embryology in relation to taxonomy? ...

Q. Embryology in relation to taxonomy? Embryological information has been used for taxonomic purposes at various levels of classification. You know of a very basic division of

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd