Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Zoonoses disease-zoonotic paramyxoviruses, Zoonotic paramyxoviruses Three ...

Zoonotic paramyxoviruses Three zoonotic paramyxoviruses (Hendra, Menangle, and Nipah viruses) emerged during 1994-2004 and all these viruses have a fruit bat reservoir. Humans are

What is the gross primary production of an ecosystem, Q. What is the gross ...

Q. What is the gross primary production of an ecosystem? How does GPP relate to photosynthesis? The Gross primary production of a GPP or ecosystem is the quantity of organic ma

What are the functional divisions of the nervous system, What are the funct...

What are the functional divisions of the nervous system? Functionally the nervous system can be separated into the somatic nervous system and visceral nervous system. The so

Illustrate about the insulin and insulin syring, Insulin, insulin syringe ...

Insulin, insulin syringe and insulin devices Insulin is the hormone used to treat diabetes mellitus. Insulin is given in the form of injection, because the gastro intestinal tr

Explain diffrent type of mycotoxins, Q. Explain diffrent type of Mycotoxins...

Q. Explain diffrent type of Mycotoxins? Mycotoxins are secondary metabolites produced by molds on foodstuffs that cause illness or death when ingested by man or animals. The pr

Explain the ecg and cheast x- ray, Explain The ECG and cheast X- Ray? ...

Explain The ECG and cheast X- Ray? The ECG and Chest X-ray: If there is a suspicion of heart disease on basis of the history or physical examination an ECG and a chest X-ray

Endoplasmic reticulum, ENDOPLASMIC RETICULUM (ER) Eucaryotic celIs have t...

ENDOPLASMIC RETICULUM (ER) Eucaryotic celIs have two major compartments- nucleus and cytoplasm. Cytoplasm was known to have no structure until the discovery of electron micrsscop

Spirochetosis (tick fever), S p ir ochetosis (tick fever) This is di...

S p ir ochetosis (tick fever) This is disease of young birds under poor management mostly reared as backyard poultry caused by a spiral bacterium, Borrelia anserina and tr

What is the life cycle of the gymnosperms, What is the life cycle of the gy...

What is the life cycle of the gymnosperms? As all plants they show a diplobiontic life cycle, i.e., alternation of generations with diploid and haploid stages. The lasting (fin

Multicausal nature of cancer, Multicausal Nature of Cancer With sever...

Multicausal Nature of Cancer With several dividing cells in the organism and the various proto-oncogenes and tumor suppressor genes that can be changed to cause cancer. one m

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd