Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

What is the constitution of the cartilaginous matrix, Q. What is the consti...

Q. What is the constitution of the cartilaginous matrix? The cartilaginous matrix is made of generally collagen type II, collagen fibers, and of proteoglycans, proteins associa

Phylum protozoa, What are some examples of organisms belonging to this phyl...

What are some examples of organisms belonging to this phylum? Please name them.

Types of neural networks, Types of Neural networks Neural networks can...

Types of Neural networks Neural networks can be grouped into: Sensory filter networks that are organised so as to pass on only certain features of a complex senso

Explain coelomates, Explain Coelomates? Recall that Acoelomates have so...

Explain Coelomates? Recall that Acoelomates have solid bodies, and Pseudocoelomates have body cavities that form between the endoderm and the mesoderm. In contrast, the body ca

Denitrification - nutrient cycles, Denitrification - Nutrient Cycles N...

Denitrification - Nutrient Cycles Nitrates are readily leached from the soil and also lost through denitrification the process by which molecular or gaseous nitrogen (N 2 ) as

Ethidium bromide, Ethidium Bromide  intercalates within structure of the nu...

Ethidium Bromide  intercalates within structure of the nucleic acids in such a manner that they fluoresce under the UV light. Ethidium bromide staining is generally used to visuali

Trypanosomes – flagellates, Trypanosomes – Flagellates The trypanosome...

Trypanosomes – Flagellates The trypanosomes are among the serious pathogens that cause high mortality among human populations and domestic animals in Africa and also in South

Endosperm with lateral haustoria, Endosperm with Lateral Haustoria In...

Endosperm with Lateral Haustoria In Monochoria, in which the endosperm development is of helobial type, the haustorium is neither chalazal nor micropylar but lateral. The cha

How to derive a mathematical equation, A microbiology student isolated a hy...

A microbiology student isolated a hypothetical bacterial cell that seems to quadruple every generation. Knowing that binary fission is an exponential function, derive a mathematica

What is yellow fever, What is yellow fever? Yellow fever is a viral inf...

What is yellow fever? Yellow fever is a viral infection that happens mainly in Central Africa and in the Amazon region of South America. It is prevented through vaccination and

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd