Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Explain vitamin a deficiency - micronutrient deficiencies, Explain Vitamin ...

Explain Vitamin A Deficiency - Micronutrient Deficiencies? Vitamin A deficiency (VAD) is a major public health problem, and the most vulnerable are preschool children and pregn

Homogeneity to the nucleic acid chains, Q. Do the phosphate and the pentose...

Q. Do the phosphate and the pentose groups give heterogeneity or homogeneity to the nucleic acid chains? What about the nitrogen- containing groups? Supported by that, which of tho

Shock, S h o c k It is defined as a generalized acute reduction in ...

S h o c k It is defined as a generalized acute reduction in the perfusion of tissues by which there is oxygen deficiency in the cells. It is characterized by reduction in e

Mucopolysaccharides, MUCOPO L YSACCHARIDES They are heteropolysacc...

MUCOPO L YSACCHARIDES They are heteropolysaccharides of high molecular weight that are gelatinous is consistency, functioning in lubrication and as sticky substances in or

Reproduction, what are the methods of seed formation

what are the methods of seed formation

Gills - respiratory organs, Gills - Respiratory Organs Gills are the s...

Gills - Respiratory Organs Gills are the specialised respiratory organs of several aquatic animals. They are found in mollusis and as well in many crustaceans. Typically gills

Describe a method of diagnosing diabetes mellitus, Q. In ancient Greece the...

Q. In ancient Greece the father of Medicine, Hypocrates, described a method of diagnosing diabetes mellitus by tasting the patient's urine. What is the physiological explanation fo

Define energy requirements during surgery, Define Energy Requirements durin...

Define Energy Requirements during Surgery? The energy requirements of the patient should be based upon his present body weight which should be followed by a comparative assessm

Historical example for scaling from individual to ecosystems, Define Histor...

Define Historical example for scaling from individual to ecosystems? Biological oceanographers have long utilized physiologically based models like the Droop model, which reduc

What is the classification of burns, What is the Classification of Burns? ...

What is the Classification of Burns? Burns can be classified on the basis of the extent, depth, patient age and associated illness or injury. On the basis of depth, burns are u

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd