Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Cost-benefit relationship regarding sewage treatment, Q. What is the cost-b...

Q. What is the cost-benefit relationship regarding sewage treatment as a strategy to fight water pollution? To treat sewage is greatly cheaper for society. The non-treated sewa

How is the excretory system of molluscs characterized, Q. How is the excret...

Q. How is the excretory system of molluscs characterized? Molluscs have one or two pair of spongelike nephridia, similar to kidneys

Describe about the detectors used in hplc, Question 1 Explain pharmacokine...

Question 1 Explain pharmacokinetic parameters observed in plasma concentration time curve Question 2 What is Gas Chromatography? Mention the quantitative applications of gas

Iron - mineral elements, IRON It is present in bread, potatoes, green v...

IRON It is present in bread, potatoes, green vegetables, especially spinach, lettuce, cocoa, raisins, red meat, liver, kidney, egg yolk etc. Iron is also available in the bo

Growth and development, details and terms used in growth and development?

details and terms used in growth and development?

Show upsloping st-segment, Q. Show Upsloping ST-Segment? There are few ...

Q. Show Upsloping ST-Segment? There are few subjects in exercise literature that has generated more controversy than the significance of up sloping ST-segments. The up sloping

Explain the parts of the microscope, Explain the Parts of the Microscope? ...

Explain the Parts of the Microscope? Microscope, as you may have noticed in Figure or for that matter even seen in a laboratory, is a metal body composed of a base and an arm t

What is lasting form in gametophyte-pteridophytes-sporophyte, What is the l...

What is the lasting form in the gametophyte, pteridophytes or the sporophyte? How can it be compared to bryophytes? The lasting form in pteridophytes is the diploid (2n) sporop

Inadequate dietary intake - cause of anaemia is dietary, Define Inadequate ...

Define Inadequate Dietary Intake - cause of anaemia is dietary? The commonest cause of anaemia is dietary inadequacy of iron. The dietary intakes arc usually half of the recomm

What is the kind of life cycle present in pteridophytes, Q. What is the kin...

Q. What is the kind of life cycle present in pteridophytes? Like all plants pteridophytes present diplobiontic (alternation of metagenesis or generations,) life cycle.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd