Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Functions of citric acid cycle, Functions of Citric Acid Cycle The citr...

Functions of Citric Acid Cycle The citric acid cycle is an amphibolic pathway  i.e.  it  is involved in both anabolic and catabolic processes

What is fern allies - equisetum, What is Fern Allies - Equisetum ? The ...

What is Fern Allies - Equisetum ? The earliest land plants are thought to have evolved from green algal ancestors, since they share many features. Both green algae and plants h

Functions of lysosomes, FUNCTIONS (1 )      Intracellular digestion -...

FUNCTIONS (1 )      Intracellular digestion - Individual cells may obtain food through phagocytosis. The same is digested with the help of lysosomes. It is of two types:-

Define role in growth and cellular differentiation, Define Role in growth a...

Define Role in growth and cellular Differentiation? The growth and differentiation of epithelial cells throughout the body are especially affected by vitamin A deficiency.  In

Fats requirements for ulcerative colitis, Q. Fats requirements for ulcerati...

Q. Fats requirements for ulcerative colitis? Usual foods, which contain fats (invisible or inherent fat), are permitted but not fried foods, as they are not easily digested due

Ethylene - apical dominance, Ethylene - Apical Dominance Ethylene also...

Ethylene - Apical Dominance Ethylene also plays a role in the inhibition of lateral bud growth. It is present in those tissues like shoot apex where auxins are also present. I

Explain mechanism of absorption of haem iron, Explain Mechanism of Absorpti...

Explain Mechanism of Absorption of Haem Iron? Haem iron is soluble in the alkaline environment of the intestine. It binds to the receptor on the enterocytes and is internalized

Define hexokinase, Hexokinase, that catalyzes the first irreversible step o...

Hexokinase, that catalyzes the first irreversible step of glycolysis, is inhibited by glucose 6-phosphate.   Thus  when  PFK  is  inhibited and  fructose  6-phosphate builds  up an

Competition - processes in succession , Competition - Processes in Successi...

Competition - Processes in Succession The aggregation of individuals in an area leads to inter specific and intra specific competition. The competition is usually for

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd