Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

What is class gastropoda in animal kingdom, What is Class Gastropoda in ani...

What is Class Gastropoda in animal kingdom? Snails and slugs are referred to as gastropods because of their characteristic body plan. "Gastro" is derived from the Greek word fo

Define principle of fehling test - reduction tests, Define Principle of feh...

Define Principle of fehling test - reduction tests? Sugars that possess a free or potentially free (those that can be converted to free) aldehyde or ketonic group have a proper

Methods of virus, How Viruses Multiply? Obligatory parasitism - Outsi...

How Viruses Multiply? Obligatory parasitism - Outside cells viruses are nonliving, inactive   particles but after entering into live cells these multiply fast by replication

How can bacteria produce human insulin, How can bacteria produce human insu...

How can bacteria produce human insulin on an industrial scale? What are the other forms of insulin made available by the pharmaceutical industry? Bacteria do not naturally synt

What are the three main types of viral hepatitis, Q. What are the three mai...

Q. What are the three main types of viral hepatitis? There are various types of viral hepatitis. The most vital epidemiologically are hepatitis A, hepatitis B and hepatitis C.

Virus, #question.bacteria and virus are meet so what happen.

#question.bacteria and virus are meet so what happen.

What are flavonols and flavones, What are Flavonols and Flavones? These...

What are Flavonols and Flavones? These are the most widely distributed among the flavonoids. The most commonly occurring are Quercetin, Myricetin and Kaempferol. Quercetin is q

What are flavanols, What are Flavanols? Examples are catechin and epica...

What are Flavanols? Examples are catechin and epicatechin. You may have heard of the benefits of tea. Some of them are due to gallic acid, which is combined with epicatechin. F

Define precautions for estimation of vitamin c in chillies, Define Precauti...

Define Precautions for Estimation of Vitamin c in Chillies? 1. Rinse all glassware with 3% metaphosphoric acid before you begin your practical and subsequently each time you wa

What is speciation, What is speciation? The Speciation is the process b...

What is speciation? The Speciation is the process by which different species emerge from a common ancestor species. The Speciation generally begins when populations of the same

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd