Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Explain yellow fever, Yellow Fever  Yellow fever vaccine, a single-dose...

Yellow Fever  Yellow fever vaccine, a single-dose attenuated live virus vaccine prepared in eggs, should be given at least 10 days before travel to endemic areas, which include

Explain cardiac prophylactic antibiotics, Cardiac Prophylactic antibiot...

Cardiac Prophylactic antibiotics can decrease the incidence of infection after cardiac surgery, and intraoperative redosing has been associated with adecreased risk of postoper

Define th technique - stage two using a mucoperiosteal flap, Stage two usin...

Stage two using a mucoperiosteal flap A Mid crestal incision over the implant site is made and reflection of mucoperisteal flap is done under local anesthesia. After locating t

Pedology, Pedology: This is the study of soil. Pedology is a type of study...

Pedology: This is the study of soil. Pedology is a type of study of soils in their natural environment. Pedology is one of two main branches of soil science and the other big is e

Cancer lung, Cancer Lung Incidence of cancer lung is more in persons ...

Cancer Lung Incidence of cancer lung is more in persons who smoke. Environmental and industrial pollution is also a risk factor in the increase in incidence. Clinic

How are bacteria are classified, Q. How are bacteria are classified accordi...

Q. How are bacteria are classified according to their need for oxygen? According to their need of oxygen bacteria are classified into anaerobic those that survive without oxyge

Explain briefly protein hydrolysates, Explain Protein hydrolysates It i...

Explain Protein hydrolysates It is valued for their superior nutritional qualities, including increased bioavailability and reduced antigenecity. Several enzymatic modification

Define the functional properties of hydrocolloids, Define the functional pr...

Define the functional properties of hydrocolloids The hydrocolloids not only have the functional properties but also have nutritional characteristics. Most polysaccharide gums

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd