Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Define sodium, Define Sodium, Potassium and Chloride - Minerals? Claude...

Define Sodium, Potassium and Chloride - Minerals? Claude Bernard was the first to draw attention to the internal environment (milieu interior), referring to the extracellular f

Define about the classification of polyphenols, Define about the Classifica...

Define about the Classification of polyphenols?  The various classes are: a) Phenolic acids and derivatives b) Flavonoids such as Flavonols and Flavones, Isoflavones and

Determine the principle of brain and behaviour, Determine the Principle of ...

Determine the Principle of Brain and Behaviour A second principle is that insight into children's adaptation can be gained through an analysis of brain behaviour relationships.

Define atherosclerosis, Q. Explain Atherosclerosis? Atherosclerosis is ...

Q. Explain Atherosclerosis? Atherosclerosis is one of the most important causes of morbidity and mortality in developed as well as in developing countries. Atherogenesis occurs

Bone formation, 3 main stages of bone formation, and explain the process of...

3 main stages of bone formation, and explain the process of these 3 stages.

Explain the factor chromosomal inheritance, Explain the factor Chromosomal ...

Explain the factor Chromosomal Inheritance? A huge step forward in our understanding of heredity came in 1902, when a biologist named Walter S. Sutton proposed that Mendel's "f

Explain about congestive cardiac failure, Q. Explain about Congestive Cardi...

Q. Explain about Congestive Cardiac Failure? It is an end stage heart disease and a significant contributor to morbidity and mortality particularly in the elderly population. C

Define the hydrogen ion concentration in red blood cells, Which of the foll...

Which of the following processes help bring oxygen to the body cells that are in a leg? A. Net flux of oxygen from blood plasma into red blood cells in the body capillaries in

Where is the defect in the argyll robertson pupil, Where is the defect in t...

Where is the defect in the Argyll Robertson pupil The defect in Argyll Robertson pupil is due to light near dissociation because pupil react better to near than light.

What is the second polar body, Q. What is the second polar body? After ...

Q. What is the second polar body? After termination of the second meiotic division of the oocyte II two cells are generated: the second polar body and the egg cell proper. The

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd