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Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain (1) fragments further from the required gene (which are discarded); (2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or (3) fragments from within required gene - the optimal result.
Q. Explain the use of Benzoates acid? Benzoic acid, sodium benzoate and the parahydroxy esters (parabens) are used as preservatives. Benzoic acid and its sodium salt, sodium be
A new drug named AGON-CaSR has been developed that is an agonist at calcium-binding sites of CaSRs (Calcium-Sensing Receptors) in plasma membranes of parathyroid gland cells.
Chronic Pulmonary Thromboembolism : The operation recommended is pulmonary thrombo endarterectomy. Indication : The main indication for surgery is when patients with chroni
Fresh Water Water, a universal solvent, invariably contains many soluble salts. In fresh water the total salt content remains under 15 percent. Different types of soluble salts
What are protein hydrolysates? Proteins that have been treated with enzymes to break them down into amino acids or shorter peptides are referred to as protein hydrolysates. Pr
The NYQUIST LIIMIT-It is a sampling phenomenon, which limits the maximum fiequemcy shift measurement to one half of the sampling frequency (PRF). By its nature, pulse wave
Recently, the media have promoted the idea of consuming only locally grown, organic produce. Are there any nutritional values that might be present in locally grown produce that mi
Structure-activity relationships Structure-activity relationships may be useful to increase the weight-of-evidence or human health hazards identification. Where classes of comp
what are the etiological agents of malaria
Explain radiation sterilization Various studies have been conducted which show the effect of processing on vitamins especially, thiamine. In one study, which compared the effec
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