Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Structure of spermatozoan, STRUCTUR E OF SPERMATOZOAN Structure of spe...

STRUCTUR E OF SPERMATOZOAN Structure of sperm is divided into 3 parts -      (1) Head                  (2) Middle piece             (3) Tail 1 .       HEAD

How is the gastric mucosa protected from the acid ph, How is the gastric mu...

How is the gastric mucosa protected from the acid pH of the stomach? The gastric epithelium is mucus secretory, i.e., it makes mucus. The mucus covers the stomach wall preventi

Percussion - criteria for endosteal implants, Percussion - criteria for end...

Percussion - criteria for endosteal implants? It is neither an indicator of clinical health nor of rigid fixation. Ringing sound that occurs on percussion corresponds to the pr

What is nucleotides, What is Nucleotides? Nucleotides are the basic b...

What is Nucleotides? Nucleotides are the basic building blocks of nucleic acids. Each nucleotide is composed of a nitrogen base, a 5-carbon sugar called a pentose, and an ass

Define types of non enzymatic browning reaction, Define Types of Non Enzyma...

Define Types of Non Enzymatic Browning Reaction? Two major types of non enzymatic browning reaction have been recognized to occur in foods during processing. 1. Maillard Rea

Edema, Ed e m a It refers to excessive accumulation of fluid in tiss...

Ed e m a It refers to excessive accumulation of fluid in tissue spaces caused by disturbance in the fluid interchange between capillaries, tissue spaces and lymphatic vessel

Permanent partial disability - injury from an accident, Permanent Partial D...

Permanent Partial Disability - Injury from an Accident Permanent partial disability restrains the worker by doing the job he has been doing. He recovers from the injury in th

What is the disease caused by dietary iodine deficiency, What is the diseas...

What is the disease caused by dietary iodine deficiency? Iodine deficiency causes hypothyroidism, an abnormally lower production of thyroid hormones that require iodine to be s

Cockroach heart, How last chamber of heart in cockroach receives blood with...

How last chamber of heart in cockroach receives blood without having ostia?

List three types of evidence used by systematic taxonomists, List three typ...

List three types of evidence used by systematic taxonomists to construct phylogenetic diagrams. Types of evidence contain the morphology of fossil and living species, patterns

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd