Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Proteins of the endoplasmic reticulum, The RER have various proteins which ...

The RER have various proteins which have the role of assisting nascent proteins to fold rightly into their native conformation. Some of these are called as chaperones. RER-resident

Explain the purpose of preparation of isolates from protein, Purpose of the...

Purpose of the preparation of isolates from a protein The major purpose of the preparation of concentrates and isolates from a protein source is to increase the concentration o

Can you define a nutrient, Q. What is a nutrient? A nutrient is every s...

Q. What is a nutrient? A nutrient is every substance used in the metabolism and which is obtaining from the diet. For example, essential amino acids and vitamins are nutrients.

Explain the molecular level, We just had to clean a food freezer in the off...

We just had to clean a food freezer in the office because *someone* put a can of Coke in the freezer and it exploded. Explain, at the molecular level, why the Coke can exploded. A

Explain prophylaxis - diarrhea, Prophylaxis Medical Letter consultants...

Prophylaxis Medical Letter consultants generally do not prescribe antibiotic prophylaxis for travelers' diarrhea, but rather instruct thec patient to begin self-treatment when

Gene interactions (post mendelian genetics), GENE INTERACTIONS (POST MENDEL...

GENE INTERACTIONS (POST MENDELIAN GENETICS) Phenotypic expression of a gene may be altered by the influence of other genes. The modification of the normal phenotype of certain

Show the collection of primary samples of grain, Q. Show the Collection of ...

Q. Show the Collection of Primary Samples of grain? Sampling of grains begins with the collection of the primary sample i.e. sample of the consignment. The process involved in

Differences between nervous system of man and rabbit, DIFFERENCE S BETWEEN...

DIFFERENCE S BETWEEN MAN & RABBIT - S.NO .   1. M A N   Brain round RABBIT   Elongated 2. Olfa

How can amine groups be classified, How can amine groups be classified? ...

How can amine groups be classified? Amines can be classify into primary amines, those to which one -R (variable radical) is attached to a -NH2, secondary amines, those where on

Define about the absorption of iron, Define about the Absorption of Iron? ...

Define about the Absorption of Iron? Before it can be absorbed, iron whether it is in the form of haem or non-haem must be released from the food matrices where it is bond with

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd