Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Describe aerobic respiration in krebs cycle, Q. Until the Krebs cycle, aero...

Q. Until the Krebs cycle, aerobic respiration can be described without mentioning oxygen, the chemical element after which the reaction gets its name. Where in the process does thi

Illustrate the name of surgical needle, Illustrate the name of surgical ne...

Illustrate the name of surgical needle The surgical needle is comprised of 3 parts: the needle point, the needle body, and the swaged (press-fit) end. Needle may be broadl

Define the dietary sources and chemical forms, Define the Dietary Sources a...

Define the Dietary Sources and Chemical Forms? Isoflavones and coumestans are the most common compounds. Soybeans and soyfoods are the most important sources, containing approx

Explain the hormonal control of the reproductive system, Explain the hormon...

Explain the hormonal control of the reproductive system in human male. Define totipotency. Verify the two different routes of regenerating plantlets from callus culture.

What are some examples of organs and tissues, What are some examples of org...

What are some examples of organs and tissues where mitosis is more frequent, less frequent or practically absent? Generally in vertebrates mitosis is more frequent in a tissue

Gametogenesis - human development, Gametogenesis - Human Development G...

Gametogenesis - Human Development Gametogenesis as you are responsive is the process of formation and development of specialized reproductive cells, ova in females and sperms

What are the sources of dietary fibre in our diet, Q. What are the sources ...

Q. What are the sources of dietary fibre in our diet? The sources of dietary fibre include whole grain cereals, legumes, whole pulses, leafy vegetables, vegetables like peas,

Seating the abutment, Q. Show the Seating the abutment? The clinician w...

Q. Show the Seating the abutment? The clinician will need to ensure that the abutment is completely seated.A radiograph may be required to confirm complete seating. Abutments u

Describe intemittent mandatory ventilation, Describe Intemittent Mandatory ...

Describe Intemittent Mandatory Ventilation (IMV) Mandatory breaths are delivered at set tidal volumes and rates, and the patient can breathe on his own in between through a un

Under which form is nitrogen fixed by living beings, Q. Under which form is...

Q. Under which form is nitrogen fixed by living beings? The Most living beings can't use molecular nitrogen to obtain nitrogen atoms. The Producers fix nitrogen primarily from

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd