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Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain (1) fragments further from the required gene (which are discarded); (2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or (3) fragments from within required gene - the optimal result.
What is the plasma membrane of the cell? What are its main functions? The plasma membrane is the outer membrane of the cell; it delimits the cell itself and a cell interior wit
Some observations seen in this fever are: 1. Massive loss of lean body mass or muscle due to tissue breakdown (250-500 g muscle tissue is lost/day) leading to excessive nitro
Information Processing in Sensory Neuron You have previously seen that the sensory neuron transmits the information it receives, as an action potential along its axon. We desc
disadvantages of protozoa in points
What is Mitosis? Mitosis is a process whereby a cell that is preparing to divide separates the duplicated pairs of chromosomes from each other so that each of the new daughte
Describe the Phylum Echinodermata in details? The Phylum Echinodermata takes its name from two words of Greek origin: "echino," ; which means "prickle" or "spine," and "derma,"
biological significant of a skeleton
Q. What is the difference between temporal summation and spatial summation of muscle fibers? What is tetany? Spatial summation is the recruiting of new muscle fibers to incr
Q. Therapeutic dose of pyridoxine? Therapeutic dose of pyridoxine (lg/day) is usually tried in all patients with hypermethioninernia and homocystinemia. For patients who do not
PSYCHOACTIVE SUBSTANCE USE DISORDERS: Drug: It is derived from a French word 'drogue'. A medical substance used in the treatment of disease. (Taber's Dictionary). 'Drug d
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