Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Microbiology, different applications of microbiology

different applications of microbiology

Similarities between pisces and amphibians, Ask question #Minimuwhat are th...

Ask question #Minimuwhat are the similarities between pisces and amphibians

Advise on rest, Advise on Rest, recreation, sleep The patient should t...

Advise on Rest, recreation, sleep The patient should take enough rest and get good sleep. Restrict the visitors so that the patient can get enough rest. Not to strain th

How can bacteria produce human insulin, How can bacteria produce human insu...

How can bacteria produce human insulin on an industrial scale? What are the other forms of insulin made available by the pharmaceutical industry? Bacteria do not naturally synt

Zoonotic diseases-viral haemorrhagic fevers (vhf), Viral haemorrhagic fever...

Viral haemorrhagic fevers (VHF) Viral haemorrhagic fevers (VHF) are caused by a diverse group of viruses belong to the families Arenaviridae, Bunyaviridae, Filoviridae and Fla

What is signal transduction, Signal transduction occurs when an extracellul...

Signal transduction occurs when an extracellular signaling molecule activates a cell surface receptor. In words, this receptor change intracellular molecules changes a response. Th

Principles of bcc, Principles of BCC · BCC should be integrated with p...

Principles of BCC · BCC should be integrated with program goals from the beginning. BCC is a necessary part of diabetes prevention, care and support programs, and providing li

Viral diseases of domestic animals, Cattle and buffalo diseases Rinde...

Cattle and buffalo diseases Rinderpest: Rinderpest is the most destructive of the virus diseases of cloven-footed animals, viz. cattle, buffaloes, sheep, goats, pigs and wil

Unicellular organisms, How was it proved in the case of Amoeba that the key...

How was it proved in the case of Amoeba that the key to the life of a cell is Nucleus?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd