Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Endomyocardial biopsy, Endomyocardial biopsy helps in understanding that ca...

Endomyocardial biopsy helps in understanding that carditis can cause CCF in patients with rheumatic heart disease but frequency of diagnostic features on EMB is found only in 17 pe

Define tests to measure muscular strength and endurance, Define Tests to Me...

Define Tests to Measure Muscular Strength and Endurance? It is important to first understand the difference between muscular strength and endurance. To know the muscular streng

Agarose gel electrophoresis, Agarose gel electrophoresis  is the method to ...

Agarose gel electrophoresis  is the method to analyze the size of the DNA (or RNA) fragments. In the presence of an electric field, bigger fragments of DNA move through a gel slowe

What are the differences between bacterial and eukaryotic, What are the dif...

What are the differences and similarities between the bacterial and eukaryotic cell membranes?

Define the properties of solutions, Define the properties of solutions ...

Define the properties of solutions Several properties of solutions are particularly important in food preparations. Amongst these are colligative properties, such as vapour pre

What are the benefits of life style modification, What are the Benefits of ...

What are the Benefits of Life Style Modification Life style modification helps in : - reduction of weight. - good sugar control. - good blood pressure control. - re

Define phospholipids, a) Lipoproteins are large molecular compounds that a...

a) Lipoproteins are large molecular compounds that are essential to the transport of cholesterol and triglycerides (TGs) within the blood. They contain a lipid core composed of TG

Molybdenum and vanadium, Molybdenum and Vanadium - Inorganic Nitrogen and S...

Molybdenum and Vanadium - Inorganic Nitrogen and Sulphur Metabolism Molybdenum must be available in nature in order to meet the demand of Mo for the formation of nitrogenase n

Uses of microbes in industry-amino acids and vitamins, Normal 0 ...

Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4

Draw a diagram that shows this arrangement, Please help with the following:...

Please help with the following: Using the letters S for ribose sugar and B for the nitrogeneus base, draw a diagram that shows the arrangement of these components into (a) a sin

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd