Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Hormonal control by insulin, Insulin  is  released  into  the  bloodstream ...

Insulin  is  released  into  the  bloodstream by  the  β  cells  of  the  pancreas  when blood glucose stages are high after feeding and stimulates glycogen synthesis to kept exces

Distinction between breathing and respiration, (a) What is the distinction ...

(a) What is the distinction among 'breathing' and 'respiration'? (b) What part do 'ventilation' and 'gaseous exchange' play in these processes?   (a) Breathing i

Mitral valve replacement -mitral valve disease, Mitral Valve Replacement : ...

Mitral Valve Replacement :  Patients who require surgery and are not candidates for BMV, CMV or OMV should have mitral valve replacement (MVR). Types of Surgery for Mitra

Explain the determination of nicotinic acid, Determination of Nicotinic aci...

Determination of Nicotinic acid The chemical methods of assay are based on colour reactions of pyridine. Nicotinic acid and nicotinamide are converted by cyanogen bromide into

Classification of wastes, Wastes are classified into following categories: ...

Wastes are classified into following categories: 1.      Biodegradable wastes: The waste materials that can be degraded by micro-organisms are called biodegradable wastes. Th

Define nutritional management of neurological disorders, Define Nutritional...

Define Nutritional Management of Neurological Disorders Your friend's aged father, over a period of time has become very confused, forgetful and is unable to do many things he

What is multi-gated equilibrium radionuclide angiography, Q. What is Multi-...

Q. What is Multi-gated equilibrium radionuclide angiography? Multi-gated equilibrium radionuclide angiography (MUGA) is a very accurate method in measuring ejection fraction. R

What is the swinging flashlight test used for, What is the swinging flashli...

What is the swinging flashlight test used for It is done to check the relative afferent pupillary defect in an eye that is blind from optic nerve disease.

Explain water and electrolyte imbalance during kwashiorkor, Explain Water a...

Explain Water and electrolyte imbalance during kwashiorkor? The total body water and especially the extracellular fluid volume are increased in all forms of PEM. At the same ti

Define about the mid-day meal programme, Define about the Mid-day Meal Prog...

Define about the Mid-day Meal Programme? The National Programme of Nutritional Support to Primary Education commonly known as the Mid Day Meal (MDM) Scheme (was launched in Aug

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd