Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Define changes associated with the skeletal system - ageing, Define Changes...

Define Changes associated with the skeletal system - Ageing? Skeletal bone loss occurs with ageing and may have serious consequences among the elderly. With ageing, there is so

What is name for interruptions for myelin sheath, In most axons, myelin she...

In most axons, myelin sheath is interrupted at intervals of about 1 millimeter or more. These interruptions are known as: a) Collaterals b) Nodes of Ranvier (pron: ron-vee-ay)

Express the monomer unit of a protein, Describe the monomer unit of a prote...

Describe the monomer unit of a protein and how monomer units are assembled into peptides.

What do you mean by alpha taxonomy, Q. What do you mean by Alpha Taxonomy? ...

Q. What do you mean by Alpha Taxonomy? This relates to the basic or preliminary classification based almost entirely on external morphology. This can be considered as the empir

How can coacervates be formed of phospholipids, How can coacervates be form...

How can coacervates be formed of phospholipids or polypeptides? Phospholipids are amphipathic molecules, i.e., they present a polar portion and a nonpolar portion. In contact w

What happens to the tsh blood level in hypothyroidism, What happens to the ...

What happens to the TSH (thyroid-stimulating hormone) blood level in hypothyroidism? Why is there enlargement of the thyroid in the endemic goiter disease? When there is low T3

Activity of dna polymerase during the replication process, Which of the fo...

Which of the following is a false statement regarding the activity of DNA polymerase during  the replication process? A. DNA polymerase reads the template strand in the 5' to 3

Define role of lipids in controlling gene expression, Define role of Lipids...

Define role of Lipids in Controlling Gene Expression? In the lipogenic pathway, the genes that encode the enzymes of the fatty acid synthase complex are co-ordinately expressed

Herbage area or vegetation cover, Herbage area or vegetation cover Her...

Herbage area or vegetation cover Herbage area or vegetation cover is an important aspect of vegetation study in understanding the nature of a community particularly in evaluat

What is insect killing jar, Insect killing jar Secure a wide-mouth glas...

Insect killing jar Secure a wide-mouth glass jar with a screw top or single which closes very tightly. Place a wad of cotton in the bottom and cover it with a round piece of ca

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd