Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Ecological adaptation in animals to aquatic environment, Ecological adaptat...

Ecological adaptation in animals to aquatic environment In the aquatic environment animals are confronted with the problem of excess water. Freshwater and marine animals try to

Obstetric ultrasound , Title Legal aspects in obstetrical ultrasound  ...

Title Legal aspects in obstetrical ultrasound  Introduction Obstetric ultrasound is an essential component of antenatal care and it is widely perceived to be associated

Calculate the molar concentration of illinic acid, Calculate the molar conc...

Calculate the molar concentration of illinic acid and of its conjugate base illinate ion (in moles/L; M) in a 0.002 M illinate buffer at pH 12.0. The pKa of illinic acid is 6.7. En

Floristic composition - qualitative characters, Floristic Composition - Qua...

Floristic Composition - Qualitative Characters One of the important qualitative characteristics of a community is its floristic composition. This broadly refers to the kind o

What are compound eyes, Q. What are compound eyes? Arthropods have comp...

Q. What are compound eyes? Arthropods have compound eyes made of several visual units called as ommatidia. Each ommatidium transmits visual information through the optic nerve

What a cell with a euploid number of chromosomes contains, A cell with a eu...

A cell with a euploid number of chromosomes contains: A.one half of a complete set of chromosomes B.several complete sets of chromosomes C.the correct number of chromosomes D.two c

Show the model of behaviour change, Behavior Change Communication (BCC) int...

Behavior Change Communication (BCC) interventions that address diabetes mellitus are designed to promote behaviors that prevent diabetes and complications of diabetes. Behavior cha

What do you mean by ventricular arrhythmias, Q. What do you mean by Ventric...

Q. What do you mean by Ventricular Arrhythmias? Considerable disagreement exists regarding the significance of resting ventricular ectopic beats. In study comparing the coronar

What do you mean by congenital long qt syndrome, Q. What do you mean by Con...

Q. What do you mean by Congenital Long QT Syndrome? There is a rare group of young patients who suddenly pass out due to a spontaneous ventricular tachycardia and often have fa

Explain the use of chlamydia in pregnancy, Use of Chlamydia in Pregnancy  ...

Use of Chlamydia in Pregnancy  Doxycycline, other tetracyclines and the flour quinolones generally should not be used during pregnancy. Azithromycin appears to be safe in pregn

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd