Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Hirudinea - feeding and digestion in annelids, Hirudinea - Feeding and Dige...

Hirudinea - Feeding and Digestion in Annelids Hirudinea involves free living and ectoparasitic leeches. Leeches are blood suckers. The digestive system contains a preoral cham

Define the visual accommodation, Q. What is visual accommodation? Visua...

Q. What is visual accommodation? Visual accommodation is the phenomenon of varying the curvature of the crystalline lens to make possible the difference of its refractivity to

Explain the occurrence of nictoinic acid, Explain the Occurrence of Nictoin...

Explain the Occurrence of Nictoinic acid Nictoinic acid occurs widely in the animal and vegetable kingdom in free as well as in bound form (in enzymes). Several animal organs

What are taenias and diseases caused by them, Q. What are taenias? What are...

Q. What are taenias? What are the diseases caused by them? The Taenias, as well know as tapeworms, are platyhelminth animals (flatworms). The major diseases caused by taenias a

Prognosis, The course and ultimate prognosis of ARF is usually directly rel...

The course and ultimate prognosis of ARF is usually directly related to the severity of carditis. The course and prognosis also depends upon recurrence of rheumatic fever. In pre-p

Evolution of man, diffrentiate between javaman and peckingman

diffrentiate between javaman and peckingman

Explain the urinary system in human body, Explain the Urinary System in hum...

Explain the Urinary System in human body? The urinary system removes the waste materials produced as a result of all the metabolic process required to sustain life. The process

How dynamic biological processes represented as network, How dynamic biolog...

How dynamic biological processes represented as network? Many dynamic biological processes throughout a wide range of ecological scales are easily represented as dynamical netw

Internal structure of the heart of man, Internal structure of the heart of ...

Internal structure of the heart of man Internally there are four chambers in the heart. The upper two chambers are called auricles and the lower two chambers are called vent

Explain difference between fats and oils, Explain the molecular difference ...

Explain the molecular difference between fats and oils. How do the differences affect their physical properties?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd