Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

What is monohybridism, What is monohybridism? Monohybridism is the stud...

What is monohybridism? Monohybridism is the study of only one feature in the crossing of two pure individuals (hybridization) for that characteristic.

Prophase, Prophase This is the first and longest phase of mitosis .At i...

Prophase This is the first and longest phase of mitosis .At its beginning  all  10 nm segments   of chromatids (= chromonemata)  of the  duplicated  chromatin fibres of interph

Male reproductive disorders-congenital impotentia genarandi, Congenital imp...

Congenital impotentia genarandi Some bulls which are otherwise normal and healthy produce semen containing spermatozoa with specific morphological abnormalities together with

Hepatitis, He p atitis Hepatitis is defined as degenerative/ inflamma...

He p atitis Hepatitis is defined as degenerative/ inflammatory processes of the liver. The clinical manifestations associated with hepatic dysfunctions results from impairmen

Combination of meat products, C o mbination of meat products Combinin...

C o mbination of meat products Combining meats and byproducts of different species to produce value added products results in complementation and supplementation of their qua

What do you mean by acute pericarditis, What do you mean by Acute Pericardi...

What do you mean by Acute Pericarditis? Ans. Acute pericarditis is defined as acute inflammation of the pericardium and is clinically characterized by chest pain, fever, t

Water pollution, Water Pollution Water is one of the most essential r...

Water Pollution Water is one of the most essential requirements for the survival of all living organisms. Water is used for household, agricultural, industrial and recreation

Determine the structural classification of bone, Structural classification ...

Structural classification of bone Macroscopically, bone tissue can be classified into two types, compact and trabecular bone. Compact bone is dense, corticated and makes up the

Tubercular meningitis , Tubercular Meningitis (TBM) Tubercular meningi...

Tubercular Meningitis (TBM) Tubercular meningitis is a serious complication of childhood tuberculosis. It usually occurs secondarily to primary infection with tuburculosi

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd