Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Zoology, classification mollusca

classification mollusca

Use of sulphur dioxide and sulphites in microorganisms, Q. Use of Sulphur d...

Q. Use of Sulphur dioxide and sulphites in microorganisms? Sulphur dioxide as a preservative in wine preparation has been in use since ancient times. It is also used in other f

Diagnosis of acute myelogenous leukemia, The most recent blood work of a pa...

The most recent blood work of a patient with a diagnosis of acute myelogenous leukemia (AML) reveals thrombocytopenia. Where is the patient most likely to experience abnormal bleed

Anti lipid drugs-peri operative problems, Anti Lipid Drugs :  The current ...

Anti Lipid Drugs :  The current thinking is that it is very important to keep lipid levels low. It helps in preventing atherosclerotic changes in venous grafts and the long-term p

Relationship of ecology with other disciplines of biology, Relationship of ...

Relationship of Ecology with Other Disciplines of Biology In order to understand the scope and relevance of ecology let us consider its position in relation to other biological

Conduction system - heart, In this unit, you have learnt that heart is a mu...

In this unit, you have learnt that heart is a muscular organ situated in thorax covering with pericardium and consist of four chambers i.e. right atrium, left atrium, right ventric

Define ailing and failing, Define ailing and failing Clinically unhealt...

Define ailing and failing Clinically unhealthy implants are classified as "ailing" or "failing". It is necessary to distinguish between an ailing versus a failing implant to de

Obelia, what is obelia write its external feature and mainly economic impo...

what is obelia write its external feature and mainly economic important

How the average number of offspring raised to adulthood, Researchers (Helle...

Researchers (Helle et al., 2004) analyzed rates of twin births in the Sami population of Northern Scandinavia during the eighteenth and nineteenth centuries. They found that (1) a

Mechanoreceptors - receptors, Mechanoreceptors - Receptors Mechanorece...

Mechanoreceptors - Receptors Mechanoreceptors involve those receptors involved in perception of touch, pressure, tension, hearing, vibration, gravity, muscle tension etc. Th

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd