Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Endocrine glands - kidney, KIDNEY S - Origin . They develop from the ...

KIDNEY S - Origin . They develop from the mesoderm of the embryo. The kidneys secrete three hormones: renin, erythropoetin and calcitriol. (i) Renin . Whenever the rat

Cells, what are golgi apparatus

what are golgi apparatus

What is arteriole diameter, The axons of all the baroreceptors in the body ...

The axons of all the baroreceptors in the body were destroyed at 2 AM.  All else is normal.  Which of the following statements is true for the system at 2:10 AM when compared to th

Procedures for diagnosis - electron microscopy, Direct demonstration of the...

Direct demonstration of the causative agent by electron microscopy (EM): Where facilities for electron microscopy are available and a viral disease is suspected, presence o

.excretion, name the blood vessel which bring waste product to kidney

name the blood vessel which bring waste product to kidney

Protozoa, disadvantages of protozoa in points

disadvantages of protozoa in points

Is nitrogen is important plant nutrients, Is nitrogen is important plant nu...

Is nitrogen is important plant nutrients Nitrogen is an important plant nutrient which is assimilated by most of the plants as nitrate and ammonium ions. Organic matter is the

Nutritional management for patient of alzheimer''s disease, Define Feeding ...

Define Feeding and Nutritional Management for patient of alzheimer's disease? Keeping the clinical manifestations of Alzheimer's disease in mind, treatment involves personaliz

Creating a zoobook, Animal class....phylum arthropoda subphylum arthropoda

Animal class....phylum arthropoda subphylum arthropoda

Minimum difference in height among any two people, Suppose that there are s...

Suppose that there are six pairs of alleles which control height and that every dominant allele adds 5cm to the stature. Assume also that the average height of an adult (with equal

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd