Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Fertilization, Fertilization is the fusion of the two gametes (sperm and o...

Fertilization is the fusion of the two gametes (sperm and ovum) to produce a zygote which develops into the new individual with a genetic heritage derived from both the parents. S

Pathogenesis of acute rheumatic fever, You have learnt about the epidemiolo...

You have learnt about the epidemiology, etiology and pathogenesis of acute rheumatic fever. Revised Jones criteria, which have major and minor criteria, are helping to diagnosis of

What are the body fat measurements, What are the Body Fat Measurements? ...

What are the Body Fat Measurements? Obesity is best classified in adults based on Body Mass Index (BMI) classification. BMI, you already know, is a measure of body jut based on

What is allele frequency, What is allele frequency? The Allele frequenc...

What is allele frequency? The Allele frequency is the percentage of appearances of an allele in the genotypes of a given population (compared to the other alleles of the studie

Explain cis-trans isomers, Explain Cis-trans isomers Atoms or groups a...

Explain Cis-trans isomers Atoms or groups are called  cis or  trans to one another when they project respectively on the same or on opposite sides of a reference plane  identi

Chemical energy to be used by the living beings on earth, Q. How is the lig...

Q. How is the light from the sun transformed into chemical energy to be used by the living beings on earth? Light from the sun is converting into chemical energy contained in o

How do you determine if a molecule is polar or non-polar, How do you determ...

How do you determine if a molecule is polar or non-polar? A polar molecule is a molecule that has a net dipole moment because of its having unsymmetrical polar bonds

Enumerate about the diseases insomnia, Enumerate about the diseases Insomni...

Enumerate about the diseases Insomnia The results from studies of people, who claim that they do not sleep, or wake up frequently from sleep show that their insomnia can have m

Molecular biology, how biochemical evidence proof DNA as a genetic material...

how biochemical evidence proof DNA as a genetic material?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd