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Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain (1) fragments further from the required gene (which are discarded); (2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or (3) fragments from within required gene - the optimal result.
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Consider the evolution of metabolic pathways. Some biologists believe that these pathways evolved from?
Circulatory Assist Devices : Intra aortic balloon pump (IAUP) was introduced by Kantrowitz (19hX). It is also known as Counter pulsation or Diastolic augmentation.
Q. How do antibodies work to neutralize antigens? The immunoglobulins or antibodies act to facilitate the destruction of antigens: they attract phagocytic leukocytes, they dire
Formation of cocoon in earthworm: In earthworm segments from 14 to 17 are swollen. Skin on these segments is thick and glandular. This is called clitellum. When ovaries ma
Plants are the source of a large variety of biochemicals which are metabolites of both primary and secondary metabolism. But secondary metabolites are of much greater interest s
Role of cell death As development of the limb proceeds waves of death or necrosis of large masses of mesodermal cells occur in certain regions at different stages. This has be
Endocarditis usually occurrs more frequently in men, gender derived ratios range from 1.6 to 2.5. The age specific incidence of endocarditis increased progressively after 30 years
Chloroplasts Like mitochondria, chloroplasts are also distinctive organelles of eucaryotic cell. But they are found only in plant cells. Chloroplasts contain membranes forming
How do homeotic genes regulate development in Drosophila? Homeotic genes code for regulatory proteins that are thought to control the rate of cell division in various body area
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