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Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain (1) fragments further from the required gene (which are discarded); (2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or (3) fragments from within required gene - the optimal result.
Adverse Effects The most common adverse effects of itraconazole are dose-related nausea and abdominal discomfort. Rash and serious hepatic toxicity can happen. The drug can ca
Barker’s in Utero Hypothesis The developmental origins of adult disease, often called as the ‘Barker hypothesis’ states that adverse influences early in development, particula
ADAP T A TIO N - Characters that make an organism to adjust well and suited to its way of life. Variation occur in living organism due to change in environment. Th
Mechanism of Stomatal Opening It has been known for over a century that stomata open because of reversible turgor changes in the guard cells. Stomata open when turgor in the g
When a fatty acid reacts with glycerol, the result is- Select one: a. Formation of an amide b. Formation of an ester c. Formation of hydrocarbon d. Formation of a th
Q. Causes of oesophagitis? The causes include tissue erosion by hydrocliloric acid (EIC1) and pepsin, with symptoms of substernal burning, cramping, pressure sensation or sever
HYOI D BONE - Also called tongue bone as lies at the base of the tonuge. One in number. Muscles of tongue and throat are attached to it. Not e :- Except
Precautions to prevent from HIV To avoid HIV infection one should practice safe sex (use of condoms). Besides a few simple precautions are given for protection against HIV inf
What is the Importance of Fungi? Fungi are widely distributed in nature. It is estimated that there are about 1.5 million species of fungi on earth. Fungi are both beneficial a
What are the values of DPD for plant cells under hypertonic, isotonic and hypotonic media? In plant cells under hypertonic medium there is loss of water for the exterior, SF >
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