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Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain (1) fragments further from the required gene (which are discarded); (2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or (3) fragments from within required gene - the optimal result.
With the help of reaction briefly explain the oxidative phase of the pentose phosphate pathway. The oxidative branch of the pathway generates NADPH and pentose-5 phosphate, th
Why did giraffes develop long necks? 1) Describe an experiment to test this hypothesis. Be explicit about the methods you will use, the setting, the time that the experiment wil
Management In case of small defects surgical treatment is not indicated because spontaneous closure may occur before one to two years of age. Patient is treated for conges
Explain the Interaction of Riboflavin with other Nutrients? Riboflavin, as already discussed under the functions, interrelates with other B vitamins, notably niacin, which r
Embryo-sac : Embryo-sac is formed from megaspore mother cell. In embro-sac, there are 7 cells arranged in 3 groups. The 7 cells are one egg (female gamete), 2 synergids,
Q. Medical Management of mitral regurgitation? Vasodilator therapy to reduce afterload may be beneficial in patients with chronic mitral regurgitation, but there is no evidence
The normal flow pattern cross-mitral valve is a tall E wave where is due to early rapid filling and small A-wave which is due to atrial contraction. E/A ratio >1. Pulmonary
Q. Is the ventricle lumen larger during diastole or during systole? During diastole the opposite occurs. The muscle fibers of the ventricles relax and the lumen of these chambe
What is the significance of Axial skeleton? The bones which make up skeleton of the main body axis of vertebrates. It comprise the cranium, vertebral column, and rib cages, How
Double Vessel Disease (DVD) : Percutaneous intervention with stetting is usually advised for these patients. However if it is left main equivalent disease or when block is close
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