Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Rigid fixation to evaluate osseointegration, Q. Rigid fixation to evaluate ...

Q. Rigid fixation to evaluate osseointegration? Is a clinical term that means absence of observed mobility. Rigid fixation indicates the absence of clinical mobility of an impl

Explain working of dietitians and nutritionists, Dietitians and nutritionis...

Dietitians and nutritionists Dietitians and nutritionists, who are associated with hospitals and clinics generally have regular work hours. At times, they may be required to wo

Can you illustrate animal and plant cells, Q. What is the name of the cytop...

Q. What is the name of the cytoplasm division in the end of mitosis and what are the differences in this process between animal and plant cells? Cytoplasm division occurs afte

Etiological factors involved in short bowel syndrome, Q. Etiological factor...

Q. Etiological factors involved in short bowel syndrome? The etiological factors involved in this disease are: • Anaemia • Osteoporosis • Stone formation • Decrease

Zoology, type study of polystomella

type study of polystomella

Do the membranes form only the outer wrapping of cells, Q. Do the membranes...

Q. Do the membranes form only the outer wrapping of cells? Lipid membranes do not form only the outer cover of cells. Cell organelles, such as the Golgi complex, lysosomes, chl

Define the role of riboflavin in antioxidant activity, Define the role of r...

Define the role of riboflavin in Antioxidant Activity? Flavoproteins also have powerful antioxidant activity from their role as precursors to FMN and FAD. Among the FAD-requiri

What is facial prosthesis, Q. What is facial prosthesis? Dental implant...

Q. What is facial prosthesis? Dental implants have prosthesis also been used for facial prosthesis which includes nasal, orbital or auricular prosthesis. Implant and bar retain

Tissue culture, Note on production of haploid by tissue culture.

Note on production of haploid by tissue culture.

Why protein requirements of athletes get increased, Why Protein requirement...

Why Protein requirements of athletes get increased? Protein requirements of athletes, particularly those engaged in strength and power events, may be increased above those of s

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd