Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Ultrasonography, Ultrasonography: Ultrasounds are sound waves wit...

Ultrasonography: Ultrasounds are sound waves with a frequency of higher than the upper range of human hearing i.e., approximately 20,000 cycles per second (20 kilohertz).

Significance of the uterine glycogen- producing glands, Q. What is the sign...

Q. What is the significance of the uterine glycogen- producing glands? The uterine glands produce glycogen that able to degrade into glucose to nourish the embryo before the co

What are the temporal factors of abnormality, What are the Temporal Factors...

What are the Temporal Factors of Abnormality Given the on going schedule of postnatal neurodevelopment, the age of the child at the time of exposure and the behaviour can have

Explain the working of human visual system, Q. Which is the part of the hum...

Q. Which is the part of the human visual system where the receptors that sense light, i.e., the photoreceptor cells, are located? How do those cells work? The photoreceptor cel

Advantages of pyramid of energy, Advantages of Pyramid of Energy A pyr...

Advantages of Pyramid of Energy A pyramid of energy must be based on determination of the actual amounts of energy that individuals take in, how much they burn up during metab

What is microtubules, What is Microtubules? Microtubules are the largest...

What is Microtubules? Microtubules are the largest intracellular fibers, with a diameter of about 25 nm (2.5 x 10-8 meters). They consist of hollow fibers composed of a protein

Inter specific incompatibility, Inter specific Incompatibility This t...

Inter specific Incompatibility This type of incompatibility is characterized by the prevention of fusion of gametes between members of different species. The incompatibility

Evolution of man, EVOLUTION OF MAN - Mammals evolved from primitive...

EVOLUTION OF MAN - Mammals evolved from primitive reptiles (therapsida) in Triassic period, about 210 million years ago. Mammals existed as inconspicuous group of small

What is the phellogen? what its function, What is the phellogen? What its f...

What is the phellogen? What its function? The Phellogen also called as cork cambium is the meristematic plant tissue responsible for the formation of the periderm (the covering

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd