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Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain (1) fragments further from the required gene (which are discarded); (2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or (3) fragments from within required gene - the optimal result.
A biologist examines a series of cells and counts 140 cells in interphase, 10 cells in metaphase, 4 cells in anaphase and 7 cells in telophase. if complete cell cycle requires 24 h
A brief history of heart surgery : The dawn of Paediatric cardiac surgery was on August 26, 1938 when Robert, Gross, at the boston Children's Hospital, ligated ductus arteriosus
Define about the Chemotherapy - Cancer? Chemotherapy results in lot of side effects. This is because the drug effects are not specific to cancer cells alone. Even the host cell
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Q. Long-term treatment of maple syrup urine disease? Special feeds containing energy and proteins without the branched chain amino acids can be given to the infants. In some in
Do fats with one or more 'kinky' tail fatty acids tend to be solid or liquid at room temperature? These are found in triglycerides forming what? Solid fats or oils? Is it opposite
Q. Show Clinical symptoms of galactosemia? Clinical symptoms of galactosemia deficiency is found to appear early in infancy. Some infants are born with cataract, jaundice and
Assessment On assessment a child with ventricular septal defect will show clinical manifestations depending upon the size of the defect. The small defects are usually asympt
Does an increase of H+ cause the hemaglobin oxygen binding curve to shift to the left or right? Explain.
Ask quesIn Cross 1, pure-breeding colored, starchy kernel plants (C1Wx/C1Wx) were crossed to plants pure-breeding for colorless, waxy kernels (c1 wx/c1 wx). The F1 of this cross we
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