Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Things to do during a cyclone, (a)   For any individual :               ...

(a)   For any individual :                  ·          We should check house, doors and windows and have them repaired whenever necessary.                  ·          We shou

Exchange transfusion, Exchange transfusion An exchange transfusion is ...

Exchange transfusion An exchange transfusion is the serial withdrawal and injection of small amounts of blood through a central vein-usually umbilical until the required volu

Devonian, Devonian  is the period of geologic time from 410 - 360 million y...

Devonian  is the period of geologic time from 410 - 360 million years before the present. Life on land diversified, with amphibians appearing late in this period of time. Plants we

Evolution of human kind, The evolution of human kind can be regarded as the...

The evolution of human kind can be regarded as the climax of phylogenic history of organisms. In the previous units of this block as well as the previous block we have detailed for

Historical example for scaling from individual to ecosystems, Define Histor...

Define Historical example for scaling from individual to ecosystems? Biological oceanographers have long utilized physiologically based models like the Droop model, which reduc

Mechanism of phloem transport, Mechanism of Phloem Transport The effic...

Mechanism of Phloem Transport The efficiency and magnitude of translocation of food material are evident from the annual yields of various crops and fruits. Now, the question

Planning of the nursing care, Planning of the Nursing Care 1) Educa...

Planning of the Nursing Care 1) Educate and teach the parents 2) Provide preoperative and postoperative care. Educate an Teach the Parents The parents may be

Explain leptospirosis, Leptospirosis It is a bacterial disease that oc...

Leptospirosis It is a bacterial disease that occurs in many domestic and wild animals, is endemic worldwide, but the highest incidence is in tropical and subtropical areas. Tr

Coordination, how does impuses reaches the brain

how does impuses reaches the brain

Do the membranes form only the outer wrapping of cells, Q. Do the membranes...

Q. Do the membranes form only the outer wrapping of cells? Lipid membranes do not form only the outer cover of cells. Cell organelles, such as the Golgi complex, lysosomes, chl

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd