Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

The accident or incident theory - accident causation, The Accident or Incid...

The Accident or Incident Theory - Accident Causation Peterson when reiterating the significance of human factors added such factors as ergonomic traps, the decision to err and

Describe cytokinesis in a plant cell, Describe cytokinesis in a plant cell....

Describe cytokinesis in a plant cell. Vesicles produced by the Golgi apparatus fuse at  the midline of the cell to form the cell plate, a  cell wall that elongates to divide th

How are living beings divided into two groups?, Q According to the cellular...

Q According to the cellular organization how are living beings divided into two groups? Cellular beings are divided into two groups, unicellular beings and the prokaryotes whos

Mode of hormone action through extracellular receptors, MOD E OF HORMONE A...

MOD E OF HORMONE ACTION THROUGH EXTRACELLULAR RECEPTORS - The molecules of amino acid derivatives, peptides or polypeptide (protein) hormones bind to specific receptor molecul

How does sexual reproduction take place in bacteria, Q. How does sexual rep...

Q. How does sexual reproduction take place in bacteria? How dissimilar are the modalities of bacterial sexual reproduction? Sexual reproduction occurs when bacteria incorporate

What is the etiological agent of cutaneous leishmaniasis, What is the etiol...

What is the etiological agent of cutaneous leishmaniasis? How is the disease transmitted and what are its typical manifestations? The etiological agent of cutaneous leishmanias

Porifera, Diagrams of organisms in phylum porifera

Diagrams of organisms in phylum porifera

Under which form is nitrogen fixed by living beings, Q. Under which form is...

Q. Under which form is nitrogen fixed by living beings? The Most living beings can't use molecular nitrogen to obtain nitrogen atoms. The Producers fix nitrogen primarily from

Physical and physiological changes - geriatric nutrition, Define Physical a...

Define Physical and Physiological Changes? Every stage has its unique requirements due to different changing needs. With respect to nutrition and health, four different basic a

Explain th eobjective of intensive care, Explain th eobjective of intensive...

Explain th eobjective of intensive care? After reading this unit, you should be able to: • know how to organize an intensive care unit; • practice effective cardio pulmonary

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd