Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Explain first and second degree burn -classification of burn, Explain First...

Explain First and second degree burns - Classification of Burns? First- and second-degree burns heal in days to weeks without scarring. Deep second- degree and small (less than

Tissue culture, Note on production of haploid by tissue culture.

Note on production of haploid by tissue culture.

Pets, Pets, Medical Research and Zoos - Wildlife Animals and plants ar...

Pets, Medical Research and Zoos - Wildlife Animals and plants are gathered throughout the world for zoos, private collectors, pet shops and researchers in biology and medicine

How are cnidarian characterized, Q. Cnidarian identity card. How are they c...

Q. Cnidarian identity card. How are they characterized according to instance of representing beings, basic morphology, kind of symmetry, germ layers and coelom, digestive system, r

Give three examples of artificial selection, Give three examples of artific...

Give three examples of artificial selection. Include examples of both animals and plants.  Answers will vary, but could include domestic cats, domestic dogs, cattle, sheep, an

Elaborate the internal vascular circulation of an eye, Elaborate the intern...

Elaborate the internal vascular circulation of an eye. Retinal vessels are derived from central retinal artery and are distributed within the inner two-third of retina. Outer o

Explain the process of determination of vitamin C, Determination of vitamin...

Determination of vitamin c Majority of chemical methods of determination is based on the rapid oxidation of ascorbic acid and therefore not too highly specific. Titration of

How do birds reproduce, How do birds reproduce? Birds, like each verteb...

How do birds reproduce? Birds, like each vertebrate, have sexual reproduction. Their embryos develop within shelled eggs having extraembryonic membranes and outside the mother'

Define the stability of your favourite protein kinase, You measure the stab...

You measure the stability of your favourite protein kinase and find that half of the protein is degraded every 10 minutes. How might you test whether the protein is degraded throug

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd