Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Consider a ph scale while answering, What is the relationship of hydrogen i...

What is the relationship of hydrogen ion concentration in tomato juice relative to lemon juice and to pure water? Be as quantitative as you can (i.e., use numbers to describe the m

Explain functional properties of food lipids, Functional properties of food...

Functional properties of food lipids Chemically, fats and oils, as you may already know by now, are a combination of glycerol and fatty acids. The glycerol molecule has three s

Define water balance - hormonal control of fluid balance, Define Regulation...

Define Regulation of Water Balance - Hormonal Control of Fluid Balance? Hormonal control of fluid balance: When water intake is insufficient or water loss is excessive, the kid

Lymph, LYMPH - Lymph is a mobile connective tissue comprising lymph pla...

LYMPH - Lymph is a mobile connective tissue comprising lymph plasma (fluid) and lymphcorpuscles (cells).   COMPOSITIO N - (i )      Lymph Plasma - It is simil

Evolution, what is ontogeny recapitulates phyloeny

what is ontogeny recapitulates phyloeny

Determine the term - neuropsychological approach, Determine the term - Neur...

Determine the term - Neuropsychological approach The neuropsychological approach relies on the use of tests in which poor performance may indicate either focal (localised) or d

Important concepts in developmental biology, DEFINITIONS E mbryolog...

DEFINITIONS E mbryology - Study of embryo is called as embryology. Zygote to emrbyo in uterus Developmental biology - Study of pre natal period & post natal period

What are the symptoms of dyslipidemia, Q. What are the Symptoms of dyslipid...

Q. What are the Symptoms of dyslipidemia? The main symptom is presence of xanthoma: This is a yellowish swelling, nodule or plaque in the skin resulting from deposits of fat. T

Endocine organ, #question.endocrine organ in crustaceans

#question.endocrine organ in crustaceans

What is the constitution of the cartilaginous matrix, What is the constitut...

What is the constitution of the cartilaginous matrix? The cartilaginous matrix is made of collagen fibers, mostly collagen type II, and of proteoglycans, proteins associated to

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd