Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Digestive system, I want to know how does our digestive system work

I want to know how does our digestive system work

Describe pathophysiology of tetralogy of fallots, Describe Pathophysiology ...

Describe Pathophysiology of tetralogy of fallots ? The PS causes concentric hypertrophy of right ventricle without enlargement. The right ventricular pressure are equal to or h

Describe the phylum chordata in animal kingdom, Describe the Phylum Chordat...

Describe the Phylum Chordata in animal kingdom? This is the other group of animals along with the Echinodermata whose anus develops prior to the mouth's development in the embr

Define traditional methods of food processing, Define Traditional Methods o...

Define Traditional Methods of Food Processing? Because food is so important to survival and most foods remain edible for only a brief period of time, people as the initial ages

What is protein targeting, The Protein targeting or protein sorting is the ...

The Protein targeting or protein sorting is the mechanism by that a cell transports proteins to the appropriate positions in the cell or outside of it. A Sorting targets can be the

Theory of embryology - baer''s law, BAER' S LAW - It was given by K.E....

BAER' S LAW - It was given by K.E. Von Baer. Von Baer was the first scientist who studied the embryology systematically. According to it, in the embryonic development of an

Define the food sources of thiamin, Define the Food Sources of Thiamin? ...

Define the Food Sources of Thiamin? Thiamin is present in many food products and depending on the amount of vitamin present, we have categorized the foods as rich, good or fair

Why haploid cell attempted to perform meiosis, What problem would most like...

What problem would most likely to occur if a haploid cell attempted to perform meiosis? a.The cell could not replicate its DNA prior to meiosis. b.The cell could not pair hom

State about the lengthy administration of test battery, State about the len...

State about the lengthy administration of test battery The lengthy administration of test battery may be unsuitable for some individuals (such as demented or psychiatric patien

What is meant by the peripheral nervous system, Q. What is meant by the per...

Q. What is meant by the peripheral nervous system (PNS)? The peripheral nervous system comprehends the ganglia and nerves of the body.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd