Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

What is mitosis, What is Mitosis? Mitosis is a process whereby a cell...

What is Mitosis? Mitosis is a process whereby a cell that is preparing to divide separates the duplicated pairs of chromosomes from each other so that each of the new daughte

BIN Report, Ask plquestion #Minimum 100 words accepted#

Ask plquestion #Minimum 100 words accepted#

Define points to keep in mind while feeding a preschooler, Define Points to...

Define Points to Keep in Mind while feeding a preschooler? 1. Do not force-feed the child. 2. Children naturally eat a variety of foods. Their sensory-specific satiety ensur

For the biological diversity is mitosis or meiosis, For the biological dive...

For the biological diversity is mitosis or meiosis the more important process? Meiosis is the cell division process that permits the formation of gametes to sexual reproduction

Structure of chromosome, STRUCTURE Each chromosome composed of two i...

STRUCTURE Each chromosome composed of two interwoven (coiled) threads called Chromonema (Chromonemata) embeded in a matrix of semisolid protein. Surface of matrix is in

How to load glycogen, How to load glycogen? Over the past fifty years, ...

How to load glycogen? Over the past fifty years, the biggest breakthrough was the discovery of how to load glycogen and sophistication in the methods of glycogen loading. Nitro

Explain the life cycle of the gymnosperms, Q. What is the life cycle of the...

Q. What is the life cycle of the gymnosperms? As all plants they present a diplobiontic life cycle that is alternation of generations with haploid and diploid stages and the la

Explain chronic infections fever, Explain Chronic Infections Fever Chr...

Explain Chronic Infections Fever Chronic  Infections Fever: These are generally of longer and sustained duration. The patients have a past history of repeated episodes or con

Determine about the sense of contrast, Determine about the Sense of  Contr...

Determine about the Sense of  Contrast It is  the ability to  perceive  slight changes  in  luminance between  regions which  are not  separated by  definite borders. This  is

How to prevent hiv-infection, HIV-Infected patients Because TB therapy ...

HIV-Infected patients Because TB therapy is complicated by co-infection with HIV, testing for HIV infection is recommended for all patients with active tuberculosis. To minimiz

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd