Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

What is cloning, What is cloning? The Cloning is the making of an organ...

What is cloning? The Cloning is the making of an organism genetically identical to another by means of genetic engineering. The foundation of cloning is the nucleus transpla

#amphibia, amphibia class characteristics

amphibia class characteristics

Explain potts shunt in palliative operations, Explain Potts Shunt in pallia...

Explain Potts Shunt in palliative operations ? This is a similar shunt done through a left thoracotomy. Anastomosis is done between left pulmonary artery aid descending thoraci

Which functional group ionization is stabilized by resonance, In which of t...

In which of the following functional groups ionization is stabilized by resonance? Select one: a. Carboxyl b. Hydroxyl c. Amine d. Aldehyde e. All of the above

Asexual reproduction, Which type of asexual reproduction takes place in mon...

Which type of asexual reproduction takes place in monocystis?

Explain significance of mitosis for embryonic development, Q. What is the s...

Q. What is the significance of mitosis for the embryonic development? Every embryo grows from a single cell that bears mitosis and generates other cells that also divide themse

Animals - rapidly flowing waters, Animals - Rapidly Flowing Waters In ...

Animals - Rapidly Flowing Waters In the exposed rock surface habitats only those organisms are found which have efficient mechanisms for staying in one place. In fact despite

Determine the nature and degree of abnormality, Determine the Nature and De...

Determine the Nature and Degree of Abnormality The nature and degree of abnormality will effect normal neural growth and maturational outcome. For example, in an adult damage t

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd