Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Define frequency of the dominant allele in this population, Industrial mela...

Industrial melanism refers to the dark pigmentation that evolved in some insects giving them protective coloration on vegetation darkened by soot in heavily industrialized areas pr

Haemorrhagic septicaemia, H a e m o r r ha g i c septicaemia ...

H a e m o r r ha g i c septicaemia It is also known as septicemic pasteurellosis or barbone and the disease is clinically characterized by high fever, excessive saliv

Importance of mitosis, Equal Distribution of Hereditary Material: In mit...

Equal Distribution of Hereditary Material: In mitosis the heredity material is equally distributed in the daughter cell. 2.No Change in Genetic Information: As there is no

Name the enzyme included in the continuous replication, Mention the informa...

Mention the information that the health workers get by measuring BOD of a water Body. a) Name the enzyme included in the continuous replication of DNA strand. Mention the Polar

Pesticides - danger to wildlife, Pesticides - Danger to Wildlife Anoth...

Pesticides - Danger to Wildlife Another recently realised danger to wildlife in many parts of the world has come from the development of more effective pesticides. As agricult

Rituals , Rituals: The social life of  the earliest human groups or tri...

Rituals: The social life of  the earliest human groups or tribes revolved around food gathering. To begin with, they must have collected anything they could eat-seeds,  nuts, f

Floating stage - hydrarch, Floating Stage - Hydrarch The pond is now c...

Floating Stage - Hydrarch The pond is now colonised by plant species which are rooted in mud but their leaves reach water surface and float. These are species of Nelumbo, Nymp

Skin., What is the epidermis..

What is the epidermis..

Continuous wave doppler, When a ventricQlar septa1 defect (VSD) is present,...

When a ventricQlar septa1 defect (VSD) is present, with no aortic stenosis, the peak velocitgr  across the defect reflects the difference in pressure between the right ventricle an

Transpiration the only way through which leaves lose water, Is the transpir...

Is the transpiration the only way through which leaves lose water? The Plants don't only lose water as vapor as by transpiration. Leaves also lose liquid water by a phenomenon

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd