Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Explain about the alzheimer''s disease, Explain about the Alzheimer's Disea...

Explain about the Alzheimer's Disease? Named after the German neurologist who first described it, Alzheimer's disease is the most common cause of progressive dementia, due to t

What are the amylase inhibitors, What are the Amylase Inhibitors? Inhib...

What are the Amylase Inhibitors? Inhibitors of the enzyme a-amylase are found in wheat, rye, beans, mango, legumes, potatoes, sorghum (jowar) and oats. Most amylase inhibitors

What is biomaterial, What is Biomaterial Biomaterial is defined, in the...

What is Biomaterial Biomaterial is defined, in the broader sense, as any pharmacologically inert material that is capable of interacting with a living organism without causing

Explain the nutrition of fungi, Explain the Nutrition of Fungi? Fungi g...

Explain the Nutrition of Fungi? Fungi grow in moist environment and are chemoorganoheterotrophs. What do we mean by chemoorganoheterotrophs? The term chemotroph describes organ

Describe the maturity stages in fish, Question 1: (a) Describe the mat...

Question 1: (a) Describe the maturity stages in fish. (b) "k" and "r" selection strategies are commonly used to describe the response of fish to biotic and abiotic cond

Define the hydrogen ion concentration in red blood cells, Which of the foll...

Which of the following processes help bring oxygen to the body cells that are in a leg? A. Net flux of oxygen from blood plasma into red blood cells in the body capillaries in

Can obesity causes the cardiovascular disease, Q. Can Obesity causes the ca...

Q. Can Obesity causes the cardiovascular disease? Obesity is established as a leading predictor of CAD and is associated with several cardiovascular risk factors like cholester

Explain rectangular full mucoperiosteal flaps, Explain Rectangular Full Muc...

Explain Rectangular Full Mucoperiosteal Flaps - Endodontic Surgery      a. Releasing and relaxing "vertical" incisions, with the Horizontal incision, b. Causes re

Alive and something that is a living organism, Is there a difference betwee...

Is there a difference between something that is alive and something that is a living organism?

Minimal distance between the implants or an implant, What should be the min...

What should be the minimal distance between the implants or an implant and a natural tooth. The minimal distance between the implant and the adjacent tooth should be 1.5 -2 mm

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd