Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Which starch is being broken down by an enzyme, In an investigation to comp...

In an investigation to compare the rates at which starch is being broken down by an enzyme    (a) what test is used    (b) how do you know when the reaction

Clinical manifestations of infective endocarditis, Clinical Manifestations ...

Clinical Manifestations i) Evidence of Systemic Infection Fever, chills, rigor, night sweat, loss of weight, arthralgia, arthritis, backache, muscle pain.  ii) Ev

Kiva, briefly explain pinocytosis

briefly explain pinocytosis

Explain advantages of using fungi as a source of protein, Organism:-Fungi  ...

Organism:-Fungi  Advantages:- Easy to harvest from culture medium. Texture of the fungi improves the functional properties of proteins. Disdvantages:-

Explain the objective of cardiac rehabilitation, Explain the OBJECTIVE of C...

Explain the OBJECTIVE of Cardiac Rehabilitation ? After going through this unit, you should be able to: 1 identifies the eligible candidate for cardiac rehabilitation and be

Zoology, what is hydrostatic skeleton?

what is hydrostatic skeleton?

Discuss about electric field, Discuss about electric field The electric...

Discuss about electric field The electric field is a vector quantity whose magnitude is the force per unit charge and points in the direction of the force on the positive test

Cut-off points to judge on failures - root canal treatment, Determine cut-o...

Determine cut-off points to judge on failures - Root Canal Treatment a)  Persistent of signs and/or symptom. b)  If in one year there is no decrease in lesion size. c)  I

Explain about folic acid, Explain about Folic acid Folic acid occurs as...

Explain about Folic acid Folic acid occurs as a yellow or orange-yellow, microcrystalline powder, almost without odour and taste. Water content of folic acid is up to 8.5%. Fol

Shrub stage - xerarch, Shrub Stage - Xerarch Sufficient soil is formed...

Shrub Stage - Xerarch Sufficient soil is formed in the herbs stage, for supporting the woody plants or the shrubs. They migrate with the help of seeds or rhizomes from the adj

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd