Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Explain pancreatitis, Explain Pancreatitis Pancreatitis :- Inflammati...

Explain Pancreatitis Pancreatitis :- Inflammation of the pancreas.

What are the hormones secreted by the adrenal medulla, What are the hormone...

What are the hormones secreted by the adrenal medulla? What are their respective functions? The medullary portion of the adrenals secretes hormones of the catecholamine group:

Principles of animal nutrition, Food Chain The land mass, water bod...

Food Chain The land mass, water bodies and atmosphere are the three endowments of nature on which the living beings have to depend for their nourishment and sustenance. The

Integrated approach plus mastering, I recently rented Physiology, An Integr...

I recently rented Physiology, An Integrated Approach and I was looking online because I have to also get the A&P access code and realize I could have rented it too with my book. Is

Post removal technique -roto-pro bur, Post removal Technique -Roto-pro bur ...

Post removal Technique -Roto-pro bur - Roto-pro bur is a taper bur having are six-sided, non-cutting flutes used a high-speed hand-piece around the circumference of the post t

Excretion, living organisms and their excretory products

living organisms and their excretory products

Proteins requirements for ulcerative colitis, Q. Proteins requirements for ...

Q. Proteins requirements for ulcerative colitis? Proteins: Patients with ulcerative colitis lose about 4-8 g fecal N2 as compared to the normal excretion of 2 g. In severe ulce

Explain about the physiology of eyelid movements, Explain about the physiol...

Explain about the physiology of eyelid movements. Physiology of Eyelid Movements: It is quoted that the eyelids move more than any other part of the body. The major movem

What is classic blalock-taussig bt shunt in shunt operations, What is Class...

What is Classic Blalock-Taussig BT Shunt in Shunt Operations ? Subclavian artery, which arises from innominate artery, is anastomosed to pulmonary artery. In a patient with lef

Define procedure for testing the presence of starch in milk, Define Procedu...

Define Procedure for Testing the Presence of Starch in Milk 1. Take 1 ml of milk sample in a test tube. 2. Add few drops of iodine solution. (2.5 gm of iodine is dissolved i

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd