Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Describe Fatty acids, In chemistry and particularly in biochemistry the fat...

In chemistry and particularly in biochemistry the fatty acid is a carboxylic acid with a long aliphatic tail (chain) that is either saturated / unsaturated. Many obviously occurrin

Which cells is the nervous tissue constituted, Q. Of which cells is the ner...

Q. Of which cells is the nervous tissue constituted? How is the generic function of this tissue related to the characteristics of the main cell type that forms it? The nervous

Sequencing of dna fragments, Q. If a fragment of nucleic acid has a nucleot...

Q. If a fragment of nucleic acid has a nucleotide sequence TAC can one assert that it is an anticodon or a codon? A nucleic acid having a TAC sequence surely is not tRNA it is

Define miscellaneous functions of protein, Define Miscellaneous Functions o...

Define Miscellaneous Functions of Protein? Besides the functions enumerated above certain other important miscellaneous functions of proteins are included herewith. These inclu

Explain about the weight imbalance, Explain about the Weight Imbalance? ...

Explain about the Weight Imbalance? You are aware that obesity is one of the major public health problems of the world, Earlier a problem of the developed nations; it is now in

Contamination of the implant body before insertion, Contamination of the Im...

Contamination of the Implant Body before Insertion The implant may be contaminated by manufacturing error, by the operator, from non titanium instrumentation and by the bacteri

Aortic allograft -biological valves, Aortic Allograft (Homograft) :  ...

Aortic Allograft (Homograft) :  In the earlier years fresh antibiotic preserved aortic allografts were tried. As the shelf life is limited, availability of all sizes at all t

Vegetative Development - Differentiation, Vegetative Development - Differen...

Vegetative Development - Differentiation It is referred to as qualitative changes that lead to increased specialisation. For example, the formation of cells and tissues of roo

Patterns of ageing and death, Patterns of Ageing and Death Plants and...

Patterns of Ageing and Death Plants and their parts develop continuously from germination until death. The latter part of the developmental process, which leads from maturity

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd