Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Reaction wood - root and shoot morphogenesis, Reaction Wood - Root and Shoo...

Reaction Wood - Root and Shoot Morphogenesis As a plagiotropic branch elongates, it might be expected to bend, downwards because of its increased weight and distance from the

Explain dietetics, Explain Dietetics Dietetics  has been defined as  t...

Explain Dietetics Dietetics  has been defined as  the science and art of feeding individuals based  on the principles of  nutrition. It can also be  said  to  be  the "science

Bty100, 1. (a) Which physicochemical properties need to be regulated by the...

1. (a) Which physicochemical properties need to be regulated by the cell? Define chemical equilibrium and discuss how it is maintained by the cell. (b) Differentiate between facili

Define nutrient requirements during emergencies, Define Nutrient Requiremen...

Define Nutrient Requirements during Emergencies? The nutritional requirements of the people do change during conditions of unforeseen stress and/or any calamity. Certain recomm

Induction of defensive barriers in plants, Induction of Defensive Barriers ...

Induction of Defensive Barriers in Plants Several polymers deposited near surface of plants form an effective barrier against invasion or stress. Cuticle (which consists of a

Prevention from infective endocarditis, Prevention of endocardial infection...

Prevention of endocardial infection by the use of antimicrobial agents, although desirable, is not always possible. By identifying the patients at  risk, the causative bacteria and

Find percentage of daughters body received first degree, The Jones family w...

The Jones family was caught in a fire but escaped. Unfortunately the father and daughter suffered burns. The father had second degree burns on his chest, abdomen, and both arms, an

Explain about the cancer, Explain about the Cancer? The word 'cancer' c...

Explain about the Cancer? The word 'cancer' comes from the Latin for crab. It refers 90 any malignant growth or tumor caused by abnormal and uncontrolled cell division. Body ce

Zone of polarizing activity (zpa), Zone of Polarizing Activity (ZPA) T...

Zone of Polarizing Activity (ZPA) The A-P axis is the 1 st axis to be fixed in the presumptive limb mesoderm at a very early stage. On the basis of results of a series of cur

Biogeochemical cycling - nutrient cycles, Biogeochemical Cycling - Nutrient...

Biogeochemical Cycling - Nutrient Cycles The energy flows through ecosystems enabling the organisms to perform various kinds of work, and is ultimately lost as heat. It is gon

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd