Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

What are the secondary roots, What are the secondary roots? In origin how t...

What are the secondary roots? In origin how the secondary roots differentiate from shoots? The Secondary roots are ramifications of the primary (major) root. The secondary root

Alleles and possible causative candidate alleles, Genome wide association s...

Genome wide association studies must account for the fact that covering the entire genome with marker loci will produce ______ associations between linked marker alleles and possib

Entamoeba histolytica, Entamoeba Histolytica Losch (1875), for the fir...

Entamoeba Histolytica Losch (1875), for the first time, described the disease symptoms of infection of Entamoeba histolytica. However, it was only in 1903 that Schaudin gave t

Explain about the celiac disease, Explain about the Celiac Disease? Cel...

Explain about the Celiac Disease? Celiac disease (also called gluten enteropathy) is an intestinal disorder that results from an abnormal  immunological reaction to gluten. u p

Proteins, what is proteins?properties of protein

what is proteins?properties of protein

Define advantages of using the plate counts method, Define Advantages of Us...

Define Advantages of Using the Plate Counts Method? 1. It is simple and sensitive method. 2. It provides viable count as only live cells will grow and produce the colony.

What is glycolysis, What is glycolysis? What are the products of this proce...

What is glycolysis? What are the products of this process? Glycolysis, the first stage of the aerobic cell respiration, is a process in which glucose is degraded (broken) to fo

Mature embryo, Mature Embryo A typical dicotyledonous embryo, as seen ...

Mature Embryo A typical dicotyledonous embryo, as seen in a median longitudinal section, consists of an embryonal axis having two broad cotyledons. The portion of embryonal ax

Describe ecosystem diversity, Q. Describe Ecosystem Diversity? Ecosyste...

Q. Describe Ecosystem Diversity? Ecosystem diversity means the variation between different types of ecosystems. Different species of animals, plants and micro-organisms interac

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd