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Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain (1) fragments further from the required gene (which are discarded); (2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or (3) fragments from within required gene - the optimal result.
There are several anaplerotic reactions required to replenish intermediates of the TCA cycle. All of the following compounds can be used for these anaplerotic reaction except: -
taxonomy of phylum echinodermata
The disease has a high morbidity and low mortality Genital disease: Affected cow develop fever, depression and stand apart, with tail held away from vulva, urination is freq
SELF - MEDICATION - Self medication refers to the use of medicines without consulting a physician. Self medication may be harmful, rather dangerous. It must be avoided. (i)
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In genetic recombination by crossing over what is the difference between parental gametes and recombinant gametes? Parental gametes are those gametes that keep the original lin
Was there molecular oxygen in the earth's primitive atmosphere? How has that molecule become abundant? The presence of the molecular oxygen in the primitive atmosphere was prob
Role of exercise in the management of diabetes mellitus Exercise is another important component of life style modification. Like diet control, regular exercise is important in
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