Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Explain about the fructnns as food ingredients, Explain about the Fructnns ...

Explain about the Fructnns as Food Ingredients? Oligosaccharides have several functional/technological attributes that give them a potential for incorporation into foods. They

Oxygen cycle, Oxygen is a major component of all living organisms. All the ...

Oxygen is a major component of all living organisms. All the organisms and plants required oxygen for aerobic respiration which they absorb from environment. Only plants release ox

Transport of macromolecules, Nuclear transport is an energy-dependent proce...

Nuclear transport is an energy-dependent process mediated through saturable receptors. Export and Import receptors are by to distinguish and bind to nuclear localization signals or

What is elongation cycle , At the starting of the first round of elon...

At the starting of the first round of elongation, the initiation codon (AUG) is positioned in the P site with fMet-tRNAfMet bound to it by codon-anticodon base pairing.  In The nex

Show the ph range of natural honey, Q. Show the pH range of natural honey? ...

Q. Show the pH range of natural honey? The pH of natural honey ranges from 3.4 to 6.1. Acidity of honey is primarily due to presence of acids such as gluconic acid, pyruvic a

Biogeochemical cycling - nutrient cycles, Biogeochemical Cycling - Nutrient...

Biogeochemical Cycling - Nutrient Cycles The energy flows through ecosystems enabling the organisms to perform various kinds of work, and is ultimately lost as heat. It is gon

How would contrast single covalent bonds, 1. In modern blimps, the gas of c...

1. In modern blimps, the gas of choice used to inflate them is helium rather than hydrogen. Hydrogen would be lighter, but helium is safer. Compare and contrast the atomic structur

draw the cell at metaphase, Consider cell with a diploid chromosome number...

Consider cell with a diploid chromosome number of 4 (2n=4), one pair of the chromosomes is metacentric,the other is acrocentric. The metacentric is labeled a 1 a 1 while the acr

1, what are the alpha taxonomy?

what are the alpha taxonomy?

Describe in detail about the unicellular eukaryotes, Describe in detail abo...

Describe in detail about the unicellular eukaryotes Animal cel1.s and many types of unicellular eukaryotes contain centrioles, which are cylindrical in structure, about 0.15 m

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd