Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Effects of flow limiting stenosis on blood flow, 1) The presence of epicar...

1) The presence of epicardial coronary artery stenosis caused by artherosclerotic plaques is by far the most frequent angiographic finding in any cardiac ischaemic syndrome. 2)

Zoology , phylum platyhelminthes

phylum platyhelminthes

In what ways is water lost from the body, In what ways is water lost from t...

In what ways is water lost from the body? Water is lost from the body by a) Evaporation (lungs and skin), b) Urination and defaecation (faeces always have water).

Organs involved in the digestion process, The various organs involved  in...

The various organs involved  in  the digestion process are: Alimentary tract which  includes mouth, pharynx, esophagus stomach, small intestine, large intestine, appendix,  rec

Determine the concept of digestion of fats, Which of the following assist i...

Which of the following assist in the digestion of fats? A. Production of bile salts in the liver and the secretion of those bile salts into the small intestine. B. Emulsific

List four common exercises you will recommend to a patient, List four commo...

List four common exercises you will recommend to a patient. Common exercises are: - brisk walking - cycling - swimming - playing tennis - dancing - rope skip

Kangroo rat, Kangroo Rat Kangroo rat Dipodornys merriami, a native of ...

Kangroo Rat Kangroo rat Dipodornys merriami, a native of South-West America is a classical example of how small mammals survive in desert. It exhibits all the osmoregulatoryad

Health promotion for the general population, Q. Health Promotion for the Ge...

Q. Health Promotion for the General Population? Targeted to have a healthy, risk free population and involves development of an effective communication strategy to modify indiv

Biota of lakes, Biota of Lakes Lakes exhibit life zones. So far you h...

Biota of Lakes Lakes exhibit life zones. So far you have been reading about the vertical zonation of lakes. The lakes can be divided into horizontal zones as well. This divis

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd