Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

What in genetics is hybridization, What in Genetics is hybridization? T...

What in Genetics is hybridization? The Hybridization in Genetics is the crossing of individuals from "pure" and different lineages in relation to a given trait that is the cros

What property of the dna fragments permits this separation, DNA can be divi...

DNA can be divide into fragments using restriction enzymes.    (a) Outline the technique used to separate these fragments.    (b) What property of the DNA f

Illustrate about insulin devices - insulin pen, Insulin Devices - Insulin P...

Insulin Devices - Insulin Pen Insulin pen is an insulin injection system. A pen consists of disposable needle, a vial of insulin and a pen. There are two pen systems replac

Main manifestations of cholera, Q. What is the etiological agent and the ma...

Q. What is the etiological agent and the main manifestations of cholera? The Cholera is a bacterial disease caused by the Vibrio cholerae. The disease is spread by fecal-oral r

Natural and artificial ecosystem, Natural and Artificial Ecosystem i) N...

Natural and Artificial Ecosystem i) Natural ecosystems are those which are mostly free from human disturbances, such as tropical forests, grasslands, oceans, lakes and deserts.

How is the skin involved in the regulation of temperature, Q. How is the sk...

Q. How is the skin involved in the regulation of body temperature? Skin is one of various organ systems participating in maintaining a core temperature, meaning the temperature

Loading and unloading of sieve tubes, Loading and Unloading of Sieve Tubes ...

Loading and Unloading of Sieve Tubes In order to understand the loading of food from manufacturing leaf cells to sieve tubes we must examine the anatomy of a minor vein shown

Nutritional management of food allergies & food intolerance, Define Nutriti...

Define Nutritional Management of Food Allergies and Food intolerance? In this unit we will be discussing the adverse reactions associated with food. You may have read or heard

Genotypically and phenotypically, 1. In the human, normal pigmentation ( A ...

1. In the human, normal pigmentation ( A ) is dominant to albinism ( a ). What results would be expected from the following matings, both genotypically and phenotypically? AA x

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd