Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Role of echocardiography, Echocardiography is a very important tool in diag...

Echocardiography is a very important tool in diagnosis of cardiovascular diseases and is used  virtually in all categories of cardiovascular diseases. There are certain areas where

Infectious bovine rhinotracheitis (ibr), Infectious bovine rhinotracheitis ...

Infectious bovine rhinotracheitis (IBR) The disease is caused by a Bovine Herpesvirus -I belonging to the family Herpesviridae and subfamily Alphaherpesvirinae. It is a DNA vir

Why dietary supplements do not speed up a child''s growth, Why Dietary supp...

Why Dietary supplements do not speed up a child's growth? Dietary supplements do not "speed up" a child's growth and development: There is no scientific evidence that me

Explain dose-scaling, Dose-scaling Toxicological equivalent doses in a...

Dose-scaling Toxicological equivalent doses in animals and humans are a debatable issue. The Joint FAOIWHO Expert Committee on Food Additives (JECFA) and Joint FA01 WHO Meetin

Maintenance in the continuing care cycle, Maintenance in the Continuing Car...

Maintenance in the Continuing Care Cycle Impaired dexterity: Any impairment of dexterity, even if it is temporary, may be detrimental to dental implants because home maintena

Define the risk reduction in cardiovascular disease, Q. Define the Risk red...

Q. Define the Risk reduction in cardiovascular disease? Ans. Weight loss by caloric restriction diets has been shown to decrease plasma CRP levels. Additional data indicat

Biodeterioration, is paper broken down by microorganisms

is paper broken down by microorganisms

Is there chloroplasts in cyanobacteria, Q. Is there chloroplasts in cyanoba...

Q. Is there chloroplasts in cyanobacteria? In cyanobacteria there is no chloroplast and the chlorophyll layers are dispersed in cytosol.

What is the gross primary production of an ecosystem, What is the gross pri...

What is the gross primary production of an ecosystem? How does GPP relate to photosynthesis? Gross primary production of an ecosystem, or GPP, is the amount of organic material

What is inharmonious ecological interaction, What is inharmonious ecologica...

What is inharmonious ecological interaction? Inharmonious, or negative, ecological interaction is that in which at least one of the participating beings is harmed.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd