Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Define mid root perforation - types of root perforation, Define Mid root (l...

Define Mid root (latral) perforation? Perforation through latral wall of the root canal during cleaning and shaping or during post space preparation

Hypomagnesaemic tetany of calves, Hypomagnesaemic tetany of calves You...

Hypomagnesaemic tetany of calves Young calves in the age group of 2-8 weeks and fed whole milk or milk replacer are more likely to develop hypomagnesaemia due to inadequate ma

What are the differentiations of the cell membrane, Q. What are the differe...

Q. What are the differentiations of the cell membrane? In some kind of cells, the cell membrane presents differentiations that are necessary for the specific functions of the c

What is an example of intraspecific competition, Q. What is an example of i...

Q. What is an example of intraspecific competition? The Intraspecific competition occurs in practically all species, for instance, the competition of humans for a job.

What is mass transportation across the cell membrane, Mass transportation i...

Mass transportation is the access or the exiting of substances in or from the cell engulfed by portions of membrane. The fusion of internal substance-having membranous vesicles wit

Describe microtubular cytoskeleton in protozoans, Protozoans have endoskele...

Protozoans have endoskeletons formed from microtubular cytoskeleton of the exoskeletons or cytoplasm secreted as shells or tests. Some of these single-cell organisms are capable of

Endocrine glands - prostaglandins, PROS T AGLANDIN S (PGS) - Beca...

PROS T AGLANDIN S (PGS) - Because they were first found in semen (which is produced partly by the prostate gland), they were named prostaglandins. Prostaglandins are d

Describe cytokinesis in a plant cell, Describe cytokinesis in a plant cell....

Describe cytokinesis in a plant cell. Vesicles produced by the Golgi apparatus fuse at  the midline of the cell to form the cell plate, a  cell wall that elongates to divide th

Usefulness of fungi for some industries, Q What is the usefulness of fungi ...

Q What is the usefulness of fungi for some industries? Fungi are industrially used in the production of fermented beverage, cheese, bread, and so on. A few fungi are very impor

Fermentation, what is steroid production by microbial metabolism

what is steroid production by microbial metabolism

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd