Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Explain epimerism, Epimerism:- Another type of stereo isomerism known ...

Epimerism:- Another type of stereo isomerism known as epimerism occurs with respect to a single asymmetric carbon atom of a monosaccharide possessing more than one asymmetric

What is the effect of physical activity on health, What is the effect of ph...

What is the effect of physical activity on health? The Surgeon General's report (1996) summarizes the effects of physical activity on health as follows. Overall Mortality: H

Explain the nervous system characterized in echinoderms, How are the symmet...

How are the symmetry and the nervous system characterized in echinoderms? Adult echinoderms, with cnidarians, are the animals that present radial symmetry, i.e., their body str

Explain emulsifying properties of proteins, Emulsifying properties of prote...

Emulsifying properties of proteins  Proteins are the surface-active substances, which are extensively used in the food industry as emulsifiers to manufacture products such as d

Are all pneumonias caused by bacteria, Q. Are all pneumonias caused by bact...

Q. Are all pneumonias caused by bacteria? The Pneumonia is the generic name of inflammation of the lungs. Moreover bacterial pneumonias, there are pneumonias caused by fungi, v

What is different about identical length and centromere, Two chromosomes in...

Two chromosomes in a cell have identical length and centromere position yet are not homologous, what is different about them.

Are there living beings without cells, Q Are there living beings without ce...

Q Are there living beings without cells? Viruses are considered the only living beings that do not have cells. Viruses are constituted by genetic material RNA or DNA enwrapped

Formation of gametes, In his experiments, Mendel noted that when two traits...

In his experiments, Mendel noted that when two traits are involved in a genetic cross, they are inherited independently of each other. The reason for this is that A. genes on the s

Haemoglobin, Haemoglobin Among the respiratory pigments we shall consi...

Haemoglobin Among the respiratory pigments we shall consider haemoglobin in some detail as this is the most familiar, widespread as well as the most efficient respiratory pigm

How can the formation of sperm cells from germ cells, Indicating the name a...

Indicating the name and respective ploidy of each involved cell how can the formation of sperm cells from germ cells be described? The formation of sperm cells, or spermatogene

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd