Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Define drug effects on food intake - anorexic effect, Define Drug Effects o...

Define Drug Effects on Food Intake - Anorexic Effect? Have an anorexic effect, either as a direct effect of the drug on appetite e.g., some antibiotics or because of side-effec

What is the importance of vitamin B6, What is the Importance of vitamin B 6...

What is the Importance of vitamin B 6 In the human and animal organisms, vitamin B 6 acts in the form of pyridoxal. In the form of 5'-orthophosphate (Pyridoxal-5'-phosphate),

Social health insurance systems, Normal 0 false false false...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Describe cell-mediated immunity, Cell-mediated immunity:  The immune reacti...

Cell-mediated immunity:  The immune reaction directed against the body cells which have been infected by viruses and bacteria; and are controlled by T cells.

Histogenesis and organogenesis, Histogenesis and Organogenesis After t...

Histogenesis and Organogenesis After the octant stage numerous cell divisions occur in various planes. The proembryo become globular or bulb-shaped. As a general rule, some ta

Amino acids and peptide bonds-protein structure, Amino Acids and Peptide Bo...

Amino Acids and Peptide Bonds, Protein Structure - The graduate can construct models of the structure and function of amino acids and peptide bonds, predict ionization of an amin

Upwelling zones of high biological productivity, Upwelling zones of high bi...

Upwelling zones of high biological productivity are found along the western coasts of the major continents. What causes this upwelling? a- cold currents moving from the equator tow

Discuss briefly the color reactions of proteins, Question 1 List various m...

Question 1 List various methods used for determination of blood glucose. Explain the principle of each test. Add a note on advantages and disadvantages of each method Question

Carbohydrates, CARBOHYDR A TES Carbohydrate = hydrate of carbo...

CARBOHYDR A TES Carbohydrate = hydrate of carbon. Hydroxyl group present. Aldehyde group or keto group may present. Carbohydrates are polyhydroxy aldehydes

What do you mean by zoological nomenclature, What do you mean by Zoological...

What do you mean by Zoological Nomenclature? This trust is housed in the British Museum, London and is responsible for some of the most important literature in Zoological Nomen

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd