Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

What are the main degenerative diseases of the heart, Q. What are the main ...

Q. What are the main degenerative diseases of the heart? The major degenerative diseases of the heart are heart failure, arrhythmias, valvular heart diseases, coronary insuffic

What are the hexoses, Q. What are the hexoses? What are some examples of he...

Q. What are the hexoses? What are some examples of hexoses with vital biological functions? Hexoses are carbohydrates whole of six carbons. Galactose, fructose and Glucose are

Health hazards with poor management of bio-medical waste, Health Hazards wi...

Health Hazards with poor management of Bio-medical waste Health hazards associated with poor management of Bio-medical waste are: - Injury from sharps to staff and waste han

Sickle Cell, Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin...

Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In de

Why plant cycle know as alternation of generations, Q. Why is the plant lif...

Q. Why is the plant life cycle known as alternation of generations? The plant life cycle is called as alternation of generations because in this cycle there are two different f

Main components of blood plasma, Main Components of Blood Plasma You w...

Main Components of Blood Plasma You would recall the various types of cells found in blood. The composition of human blood plasma is given in Table. The very structure of bloo

Carbohydrate digestion, Carbohydrate Digestion Simple sugars like gluc...

Carbohydrate Digestion Simple sugars like glucose and fructose can be absorbed and metabolised directly but disaccharides such as sucrose or lactose and polysaccharides such a

Explain about the acesulfame k - artificial sweeteners, Explain about the A...

Explain about the Acesulfame K - Artificial Sweeteners? Acesulfame-K (potassium salt of 6-methyl-1, 2, 3-oxathazin-4(3H)-one 2, 2 dioxide) is a sweetener which is commonly used

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd