Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Materials handling and storage, Materials Handling and Storage Materi...

Materials Handling and Storage Material handling is a very significant process in working place. The materials are handled in not finished, semi finished and finished states.

What do ypu know about conduction disturabances, Q. What do ypu know about ...

Q. What do ypu know about Conduction Disturabances? During exercise there is an increase in the sympathetic drive and a withdrawal of vagal tone. Sympathetic enhancement of con

Admission to the hospital - nursing, Admission to  the Hospital The ...

Admission to  the Hospital The  philosophy of  childcare, whether in the home, hospital, or  other community agency, should be consistently one of concern and support for the

Tagmatization, sample assignment on tagmatizatio

sample assignment on tagmatizatio

Human heart is partially non-functional, If due to some injury the chordae ...

If due to some injury the chordae tendinae of the tricuspid valve of the human heart is partially non-functional, what will be the immediate effect? 1. The flow of blood into t

Determine the biologic response, Determine the biologic response The bi...

Determine the biologic response The biologic response can include: i) Metabolic disturbance. ii) Inflammatory response iii) Immune response iv) Mutagenesis v) Ca

Biological significance of incompatibility, Biological Significance of Inco...

Biological Significance of Incompatibility Both interspecific and intraspecific incompatibility determines the degree of inbreeding and out breeding of plants. Self-incompati

Soil pollution, Soil is upper crust of earth which support land plants and ...

Soil is upper crust of earth which support land plants and animals. It is defined as addition of substances to the soil, which adversely affect physical, chemical? And biologica

Results of mitral valve replacement-mitral valve replacement, Results o...

Results of Mitral Valve Replacement: The risk of mitral valve replacement is reported as 3-5 per cent. It also depends on multiple factors like age, functional clas

State the term in broad - lunule, State the term in broad - Lunule. In ...

State the term in broad - Lunule. In sand dollars, notches or holes which pass through the body of the animal. Their function is not fully understood though may be involved in

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd