Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Why haploid cell attempted to perform meiosis, What problem would most like...

What problem would most likely to occur if a haploid cell attempted to perform meiosis? a.The cell could not replicate its DNA prior to meiosis. b.The cell could not pair hom

Explain serum lipoprotiens, Explain Serum lipoprotiens Serum lipoprot...

Explain Serum lipoprotiens Serum lipoprotiens:- spherical  or  ellipsoidal  particles containing  proteins, cholesterol esters  and  triacylglycerols, encased  within  a mon

Describe circulatory system, Circulatory system:  One of the eleven major b...

Circulatory system:  One of the eleven major body organ systems in animals; carbon dioxide, nutrients, transports oxygen, and waste products between the cells and the respiratory s

Control of pollution, Control of Pollution We have seen that pollution...

Control of Pollution We have seen that pollution affects human health, 'vegetation, crop yield, trees, fisheries, forests, buildings, archaeological monuments, tourism. These

Tolrance, geographical range graph on minimum and maximum range of toleranc...

geographical range graph on minimum and maximum range of tolerance

State cryptobiosis and explain the function of it, State Cryptobiosis and e...

State Cryptobiosis and explain the function of it. A dormant, or suspended, state of animation which allows some animals to survive severe conditions like extremely low tempera

Tricuspid valve - heart, It is made up of three cusps, anterior, posterior ...

It is made up of three cusps, anterior, posterior and septal. The septal cusp is attached to the medial margin. The anterior cusp is attached to the superior-lateral part of the ma

How are the concepts of the dna, Q How are the concepts of the DNA, gene, a...

Q How are the concepts of the DNA, gene, and proteins characteristics of living beings related? Characteristics of organisms depend on chemical reactions that take place in the

Explain about listeria monocytogenes infection, Explain about Listeria mono...

Explain about Listeria monocytogenes infection Listeria monocytogenes is a gram-positive, motile, non-spore forming rod. It is widely distributed in nature and can be found on

Explain about the deuteromycota - fungi, Explain about the Deuteromycota - ...

Explain about the Deuteromycota - Fungi? Deuteromycota - Deuteromycetes or fungi imperfecti reproduce by means of conidia. These have either lost the capacity for sexual reprod

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd