Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Explain about precautionary principle, Q. Explain about precautionary princ...

Q. Explain about precautionary principle? The ethical values of biodiversity highlights the intrinsic value of biodiversity for its own sake and it is independent of the varied

Define ergogenic and for training and competition, Define Ergogenic and for...

Define Ergogenic and for training and competition? There is always our desire to work with the body more .than its capability. This is more so in case of athletes. They wish to

Upwelling zones of high biological productivity, Upwelling zones of high bi...

Upwelling zones of high biological productivity are found along the western coasts of the major continents. What causes this upwelling? a- cold currents moving from the equator tow

Why is a balanced frequency of different alleles of a gene, Why is a balanc...

Why is a balanced frequency of different alleles of a gene in a population more useful for the survival of that population facing environmental changes? For the trait condition

Define nutritional requirements for young and older children, Define Nutrit...

Define Nutritional requirements for Young and Older Children? Young children need 3 en%, which would be easily met from 8-10 g of oil. However, more visible oil is needed to im

Yersinia pestis, what the advantage of yersinia pestis

what the advantage of yersinia pestis

Disability evaluations after injuries, Disability evaluations after injurie...

Disability evaluations after injuries: (a) Explain the following terms: "duration of disability" and "degree of disability". (b) Explain how degrees of disability after injur

Female reproductive system - graffian follicle, GRAFFIAN FOLLICLE - ...

GRAFFIAN FOLLICLE - It appears as knob or stigma in medulla. It is round, discovered by Graff. It is covered by 2 layers - thecae externa & theca interna. From theca i

Compare and contrast covalent and ionic bonds, Compare and contrast covalen...

Compare and contrast covalent and ionic bonds in molecules, give an example of each.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd