Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Determine the expected genotypic and phenotypic results, 1. In guinea pigs,...

1. In guinea pigs, black coat color (B) is dominant to white (b), and a rough coat (R) is dominant to smooth (r). What are the expected genotypic and phenotypic results of the foll

Simple precautions to prevent injuries, When resheathing needles, simple pr...

When resheathing needles, simple precautions to prevent injuries are to: 1. use only one hand to scoop the cap 2. hold the sheath with a hemostat (suggested but will require

Commensalism, #quesWhat benefits can commensalism offer to a species..

#quesWhat benefits can commensalism offer to a species..

Explain the Synthetic and natural materials of suturing, Explain the Synthe...

Explain the Synthetic and natural materials of suturing 1. Most common are synthetic fibers: nylon, polyester, polyglactin (PG), and polyglycolic acid (PGA). 2. Natural: sil

World conservation strategy proposes various steps , WORL D CONSERVATION S...

WORL D CONSERVATION STRATEGY PROPOSES THE FOLLOWING STEPS - 1.       Preservation of critical habitats. 2.       Protection of wild life in situ (in natural habitats) as we

Fertilization in earthworm, In earthworms, when the ovaries mature, the cli...

In earthworms, when the ovaries mature, the clitellum secretes a viscous substance in the form of a girdle. This girdle hardens in to a cocoon around the clitellum. The ova are dis

What is short bowel syndrome, Q. What is Short Bowel Syndrome? Short bo...

Q. What is Short Bowel Syndrome? Short bowel syndrome is a group of problems affecting people who have /had half or more of their small intestine removed. The massive resection

What are the major types of lipids, Q. What are the major types of lipids? ...

Q. What are the major types of lipids? The main types of lipids are phospholipids, triglycerides (fats and oils), waxes and steroids.

About ribosome, Which type Ribosome occurs exclusivley in Mitocondria?

Which type Ribosome occurs exclusivley in Mitocondria?

Briefly describe about the micro minerals, Briefly Describe about the Micro...

Briefly Describe about the Micro Minerals? The last unit focused on the macro minerals. Now in this unit we will study about the micro minerals, namely, iron, zinc, copper, sel

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd