Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Basic principles involved ark, Q. Basic principles involved ark? The ba...

Q. Basic principles involved ark? The basic principles involved ark: The individual must be treated as such and for that careful initial history - daily living situation, a

Classification, list the major species of echinodermata

list the major species of echinodermata

What are the two divisions of the autonomic nervous system, What are the tw...

What are the two divisions of the autonomic nervous system? The autonomic nervous system is separated into the sympathetic nervous system and the parasympathetic nervous system

What are the two groups of defense mechanisms of the body, What are the two...

What are the two groups of defense mechanisms of the body against foreign or harmful agents? What is the difference between them? The body has many defense mechanisms against f

Heterospermy, What is heterospermy?also give its significance?

What is heterospermy?also give its significance?

What do adp and atp mean, Q. What do ADP and ATP mean? What are the functio...

Q. What do ADP and ATP mean? What are the functions of these molecules for the cellular energetic metabolism? ADP is an short form of adenosine diphosphate, two molecules of ph

Name the process in that substances carry across membrane, Substances which...

Substances which are insoluble in a membrane are carried across membrane with concentration gradient by means of a carrier molecule in a process termed as: a) Diffusion. b)

Define pacinian corpuscules, Q. Define Pacinian corpuscules? Pacinian ...

Q. Define Pacinian corpuscules? Pacinian corpuscules are an example of sensory receptors scattered deep in the subcutaneous tissue underlying skin or in viscera.  These mech

Define about the zinc deficiency, Define about the Zinc Deficiency? Evi...

Define about the Zinc Deficiency? Evidence suggests that nearly one-third of preschool children in lower-income countries have stunted growth, and that a considerable proportio

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd