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Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain (1) fragments further from the required gene (which are discarded); (2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or (3) fragments from within required gene - the optimal result.
Please help with the following: Using the letters S for ribose sugar and B for the nitrogeneus base, draw a diagram that shows the arrangement of these components into (a) a sin
Solitary and Colonial Forms Animals may lead their lives either like individuals or in groups. While they exist as individuals, they are termed as solitary, but if they live i
Q. Mismatch and Recombinational repair? Mismatch repair: 1. Mismatches can take place when DNA polymerase inserts wrong nucleotide during replication 2. Mismatch repair is
Define Clinical Manifestations and Nutritional Problems Associated with Cancer? In the previous section we learnt that cancer results in several changes in the metabolism of ca
Explain the Conveyor (or Band) Dryers? In the conveyor (or band) dryer, the product is distributed on a moving belt, typically of a perforated plate, that passes through a tunn
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What is pleiotropy? Pleiotropy (or pliotropy) is the occurrence in which a single gene conditions several dissimilar phenotypical traits. Some phenotypical traits might be s
The disease has a high morbidity and low mortality Genital disease: Affected cow develop fever, depression and stand apart, with tail held away from vulva, urination is freq
NERV E FIBRES - Axon or dendrite of a nerve cell covered with one, two or three sheaths is called nerve fibre. Dendrites are surrounded only by one sheath. An axon may b
Q. Consequences on the bony structures? Basal bone forms the dental skeletal structure. Wolff's law states that the bone remodels in relationship to the forces applied. With a
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