Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Statistical investigation, Meaning of Statistical Investigation: An inv...

Meaning of Statistical Investigation: An investigation means a systematic search for the knowledge or the truth. In statistical investigation the search for the knowledge is do

Explain restaurant deep fat frying evaluation, Restaurant deep fat frying e...

Restaurant deep fat frying evaluation A number of factors are studied when evaluating frying oils. During deep fat frying, the fat is exposed continuously to elevated temperat

Procaryotic structure and diversity, Procaryotic Structure and Diversity ...

Procaryotic Structure and Diversity The first organisms which did not have well defined nucleus, called procaryotes, (pro = earlier, caryon = nucleus) were probably anaerobic a

Why immune response involves the activities of proteins, The immune respons...

The immune response involves the activities of proteins, cells, and the lymphatic system.

What are the main events of the first mitotic period, What are the main eve...

What are the main events of the first mitotic period? The first mitotic period is prophase. During prophase the following events happen: migration of each centriole pair (centr

What are the aerobic and anaerobic exercises, Aerobic and Anaerobic Exercis...

Aerobic and Anaerobic Exercises Generally, there are two types of exercises: - Aerobic - Anaerobic Aerobic exercises are those in which the patient spends calories fro

Available and non-available water, Available and Non-available Water Yo...

Available and Non-available Water You have seen above that water is present even in the apparently dry soils but it is of not much use as far as the plants are concerned. They

Organs involved in the digestion process, The various organs involved  in...

The various organs involved  in  the digestion process are: Alimentary tract which  includes mouth, pharynx, esophagus stomach, small intestine, large intestine, appendix,  rec

Nutrition - heterotrophic nutrition, HETEROTROPHI C NUTRITION Animals ...

HETEROTROPHI C NUTRITION Animals derive organic food materials by consuming products of plants - Heterotrophic nutrition. T ype s of Heterotrophic Nutrition (i ) H

Biochemical changes associated with senescence, Biochemical Changes Associa...

Biochemical Changes Associated with Senescence When senescence begins many physiological and biochemical changes take place. For example, one of the important changes observed

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd