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Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain (1) fragments further from the required gene (which are discarded); (2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or (3) fragments from within required gene - the optimal result.
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How is extracellular digestion related to cellular and tissue specialization? Several of specialized cells and tissues appeared with extracellular digestion to give enzymes and
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What is the etiological agent of visceral leishmaniasis? How is the disease transmitted and what are its typical manifestations? Visceral leishmaniasis is caused by the protozo
Q. How to investigate aortic stenosis by Exercise Testing? Exercise testing is relatively contraindicated in patients with aortic stenosis. Its diagnostic accuracy to pick up a
Define Dietary and Non Dietary Factors - Causation of Cancer? Several dietary and non-dietary factors (including genetics) can increase the risk in the causation of cancer. Som
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Triacylglycerols, cholesterol and phospholipids are associatively insoluble in aqueous solution. Thus, they are transported around the body in the blood as parts of lipoproteins.
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