Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Male reproductive disorders-preputial prolapse, Preputial prolapse Thi...

Preputial prolapse This deformity is seen in some of the tropical zebu breeds but is not uncommon in European breeds. Initially, it begins as a temperory eversion of a small p

Zoonotic diseases-yellow fever, Yellow fever Yellow fever also known a...

Yellow fever Yellow fever also known as Black Vomit and American plaque is a viral disease primarily of monkeys and transmitted to man by female Aedes mosquitoes. It is caused

What is increase in the second messenger, When glucagon binds its receptor ...

When glucagon binds its receptor there is an increase in the second messenger, cAMP. cAMP levels can be decrease by which of the following enzymes? -adenylate cyclase -PDK1

Explain eicosanoids, Explain Eicosanoids Eicosanoids are the  local h...

Explain Eicosanoids Eicosanoids are the  local hormones formed  by  body  tissues during self-healing responses  to  stimuli.  Eicosanoids are  a family  of  compounds  deriv

Test tube baby, TEST TUBE BABY - Ova are fertilized in laboratory di...

TEST TUBE BABY - Ova are fertilized in laboratory dish (in vitra) containing a nutrient broth . It may be artificial insemination donor (AID) / Artificial insemination h

Define features of male and female ascaris lumbricoides, Define Features of...

Define Features of male and female ascaris lumbricoides? i)  Ascaris  lumbricoides is  commonly called  round worm. ii)  Body  is elongated, cylindrical,  tapering at  bot

Patent ductus arteriosus , Patent Ductus Arteriosus  (PDA)   PDA is one...

Patent Ductus Arteriosus  (PDA)   PDA is one of  the most common cardiac anomalies. It occurs twice as frequently in girls as in boys.  In patent ductus Arteriosus there is

How are reptilia characterized, Q. Class Reptilia identity card. How are th...

Q. Class Reptilia identity card. How are they characterized according to examples of representing beings, basic morphology, skin, respiration, circulation, nitrogen waste, thermal

Explain the acid fast staining, Explain the Acid Fast Staining? Acid fa...

Explain the Acid Fast Staining? Acid fast staining is a type of differential staining used for identification of certain bacteria, e.g. Mycobacteria which cannot be stained rea

Atoms, the mass number is used to calculate the number of _________in one a...

the mass number is used to calculate the number of _________in one atom of an elemement. In order to calculate the number of neutrons you must subtract the _______from the ______.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd