Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Define vapor-pressure lowering and osmotic pressure, Define Vapor-pressure ...

Define Vapor-pressure lowering and Osmotic pressure? 1. Vapor-pressure lowering: the decrease in the vapor pressure of a solution containing nonvolatile solutes, compared to th

Pennetula, identifying characters of pennetula

identifying characters of pennetula

Functions of endosperm, Functions of Endosperm The tissue of young en...

Functions of Endosperm The tissue of young endosperm is rich in food materials and various growth hormones. It regulates the precise mode of embryo development and nourishes

Gastro epiploic artery and inferior epigastric artery, Gastro Epiploic arte...

Gastro Epiploic artery GEA is seldom used now. Patency has been reported as 94 per cent at one year, 88 per cent at five years and 83 per cell1 at ten years. Inferior Epiga

Hypertension, Define hypertension, discuss its causes and explain its effec...

Define hypertension, discuss its causes and explain its effects on the body. What role, if any, does medical imaging play in hypertensive patients? Explain and give examples.

Can you explain yersinia enterocolitica gastroenteritis, Q. Can you explain...

Q. Can you explain Yersinia Enterocolitica Gastroenteritis? Yersiniosis is an infectious disease caused by a bacterium of the genus Yersinia. Most human illness is caus

Cyanide - enzyme-activity control, Cyanide - Enzyme-activity Control P...

Cyanide - Enzyme-activity Control Plants generate cyanide from cyanogenic glucides and histidines. Ethylene biosynthesis is also accompanied by cyanide production. Nitrate red

Express the term - amnion, Express the term - Amnion One of the extraem...

Express the term - Amnion One of the extraembryonic membranes found in terrestrial vertebrate. The amnion is filled with fluid and the developing embryo of reptiles, birds, and

Explain japanese encephalitis, Japanese encephalitis  Japanese encephal...

Japanese encephalitis  Japanese encephalitis is an uncommon but potentially fatal mosquito-borne viral disease that occurs in rural Asia, especially near pig farms and rice pad

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd