Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Penetrating injury, Penetrating Injury Open pneumothorax (sucking c...

Penetrating Injury Open pneumothorax (sucking chest wound)  Hemothorax  Tracheobrochiaf injury  Pulmonary contusion  Mediastinal injury

What would be its final volume, Consider a simple spherical model cell that...

Consider a simple spherical model cell that consists of cytoplasm and a plasma membrane. The cell's initial volume is 2 nL and contains 0.2 M protein. The cell is placed in a la

Father, who is the father of science

who is the father of science

Coarctation of aorta, Careful palpation of the upper and lower limb pulses ...

Careful palpation of the upper and lower limb pulses would make one suspect coarctation as the cause of hypertension. The lower limb pulses are weak and delayed. Confirmation ca

Illustrate the major events of the final mitotic period, Q. What are the ma...

Q. What are the major events of the final mitotic period? The final mitotic phase is the telophase. In the telophase the following events occur decondensation of chromosomes ea

Changes in animal life during xerosere, Changes in Animal Life during Xeros...

Changes in Animal Life during Xerosere Just like the hydrosere, there occur successive changes in animal life during the xerosere. A few mites are usually found associated wi

Merits and demerits of system classification, Q. Merits and Demerits of sys...

Q. Merits and Demerits of system classification? Merits The merits of this system\are as under: • Careful observation and original description of the genera from living

Floral apex, Floral Apex Each plant must pass through a minimal 'ripe...

Floral Apex Each plant must pass through a minimal 'ripeness to flower' stage. That is, even to perceive and respond to a specific photoperiodic regime, a plant must be ready

Ttt, respiration.

respiration.

What are the causes of obesity - etiology, What are the causes of obesity -...

What are the causes of obesity - Etiology? However simple the question may sound, the answer to it is not all that simple. We cannot deny that excess weight results from positi

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd