Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Show the embryological evidence, Q. Show the Embryological Evidence? Em...

Q. Show the Embryological Evidence? Embryology is the study of the successive stages of sporogencsis , gametogenesis and the growth and development of the embryo. The number o

What is endocytosis, Which of the following is true for endocytosis? A....

Which of the following is true for endocytosis? A. During endocytosis of GLUT4 transporters in fat cells, there is removal of GLUT4 transporters from plasma membranes. B. Du

Adrenocortical steroids - vertebrates, Normal 0 false false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Explain chronic infections fever, Explain Chronic Infections Fever Chr...

Explain Chronic Infections Fever Chronic  Infections Fever: These are generally of longer and sustained duration. The patients have a past history of repeated episodes or con

Metabolism, The main constituents of food are carbohydrates, lipids, and pr...

The main constituents of food are carbohydrates, lipids, and proteins but they are found in complex forms that cannot be directly utilized by the body. Hence, they are broken down

Explain phylum tracheophyta, Phylum Tracheophyta Tracheophytes mean vas...

Phylum Tracheophyta Tracheophytes mean vascular plants. Tracheophyta includes ferns, the gymnosperms and the flowering plants. They have appeared some 400 million years ago, an

Flavour of food product, Q. Flavour of food product? Flavour factors in...

Q. Flavour of food product? Flavour factors include both sensations perceived by the tongue, which include sweet, salty, sour and bitter tastes and aromas perceived by the tong

Fertilization in earthworm, In earthworms, when the ovaries mature, the cli...

In earthworms, when the ovaries mature, the clitellum secretes a viscous substance in the form of a girdle. This girdle hardens in to a cocoon around the clitellum. The ova are dis

Structure of the vascular cambium, Structure of the Vascular Cambium T...

Structure of the Vascular Cambium This meristem, in the anatomical sense of the term usually includes two histologically distinct kinds of cells: i) Fusiform Initials, i

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd