Children with infective endocarditis, Biology

Assignment Help:

Among neonates, IE typically involves the tricuspid valve of structurally normal hearts and is associated with very high mortality rates.  It is likely that many of these episodes arise as a consequence of infected intra venous and right heart catheters as well as cardiac surgery. The vast majority of children with IE occurring after the neonatal period have identifiable structural cardiac abnormalities. Rheumatic heart disease is the major predisposition for IE in developing countries. Congenital heart abnormalities, particularly those involving the aortic valve; ventricular septal defects; tetralogy of Fallot; and other complex structural anomalies associated with cyanosis (TGA, single ventricle) are found in remaining cases. Of children with IE on congenital defects, 50 per cent develop infection after cardiac surgery; in these children, infection frequently involves prosthetic valves, valved conduits, or synthetic patches. Mitral valve prolapse generally in association with a regurgitant murmur has been recognized to predispose to IE in children.

Endocarditis among neonates is caused primarily by S.aureus, coagulase-negative staphylococci, and group B streptococci.  Occasionally infection is caused by  gram- negative bacilli and candida species. Among older children, streptococci, the predominant cause account for at least 40 per cent of cases, and S. aureus occurring as a nosocomial or community acquired  acute infection is the second most common cause of IE.

The clinical features and echocardiographic findings of IE in children are similar to those noted among adults with NVE or PVE, respectively. In contrast, IE among neonates is more cryptic; the clinical  picture is dominated  by  bacteremia, and classical signs of  IE  are  rare.


Related Discussions:- Children with infective endocarditis

How bone implant interface can be evaluated, How bone implant interface can...

How bone implant interface can be evaluated 1) Evaluation of the bone - implant interface can be done by following: i) Implant mobility and discomfort a)  Clinical implan

Non migrainous vascular headaches, Non Migrainous Vascular Headaches Th...

Non Migrainous Vascular Headaches This headache associated with dilation of the cranial arteries and can be induced by a wide variety of diseases and conditions. The most commo

What is the need of monitoring and surveillance, What is the need of Monito...

What is the need of Monitoring and Surveillance? Monitoring, we know, is the act of observing something and sometimes keeping a .record of it while surveillance is a repeated s

Elaborates congenital aortic stenosis in details, Elaborates Congenital Aor...

Elaborates Congenital Aortic Stenosis in details? More common in males (4: 1). High incidence of Bicuspid Aortic valve. Murmur present from early infancy and sometimes at birth

Procaryotes to eucaryotes, PROCARYOTES TO EUCARYOTES Procaryotes are th...

PROCARYOTES TO EUCARYOTES Procaryotes are the simple, unicellular organisms which do not have well defined nucleus, whereas eucaryotes are the complex;multicellular organisms w

Define pseudo-yeasts, Q. What are the Pseudo-yeasts? These are like tru...

Q. What are the Pseudo-yeasts? These are like true yeasts but do not form spores. All the members of this group are particularly unsuitable for fermentation purposes as they p

Define osseointegration and its theories, Q. Define osseointegration and it...

Q. Define osseointegration and its theories? Osseointegration implies that "it is a contact established without interposition of non bony tissue between normal remodeled bone a

What is the estimated percentage of water in the human body, Q. What is the...

Q. What is the estimated percentage (in mass) of water in the human body? Is this percentage expected to be larger in the adult or in the old individual? Approximately 65% of t

Reproduction, Which are the larval stages of Porifera?

Which are the larval stages of Porifera?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd