Children with infective endocarditis, Biology

Assignment Help:

Among neonates, IE typically involves the tricuspid valve of structurally normal hearts and is associated with very high mortality rates.  It is likely that many of these episodes arise as a consequence of infected intra venous and right heart catheters as well as cardiac surgery. The vast majority of children with IE occurring after the neonatal period have identifiable structural cardiac abnormalities. Rheumatic heart disease is the major predisposition for IE in developing countries. Congenital heart abnormalities, particularly those involving the aortic valve; ventricular septal defects; tetralogy of Fallot; and other complex structural anomalies associated with cyanosis (TGA, single ventricle) are found in remaining cases. Of children with IE on congenital defects, 50 per cent develop infection after cardiac surgery; in these children, infection frequently involves prosthetic valves, valved conduits, or synthetic patches. Mitral valve prolapse generally in association with a regurgitant murmur has been recognized to predispose to IE in children.

Endocarditis among neonates is caused primarily by S.aureus, coagulase-negative staphylococci, and group B streptococci.  Occasionally infection is caused by  gram- negative bacilli and candida species. Among older children, streptococci, the predominant cause account for at least 40 per cent of cases, and S. aureus occurring as a nosocomial or community acquired  acute infection is the second most common cause of IE.

The clinical features and echocardiographic findings of IE in children are similar to those noted among adults with NVE or PVE, respectively. In contrast, IE among neonates is more cryptic; the clinical  picture is dominated  by  bacteremia, and classical signs of  IE  are  rare.


Related Discussions:- Children with infective endocarditis

What is biotic potential, Q. What is biotic potential? The Biotic poten...

Q. What is biotic potential? The Biotic potential is the capability of growth of a given population under hypothetical optimum conditions, i.e., in an environment without limit

Tranquillizers - psychological drug dependence, TRANQUILLIZER S - Thes...

TRANQUILLIZER S - These are the drugs that reduce tension and anxiety, bring calmness without inducing sleep. (i) Phenothiazines - These are anti psychotic drugs.

Elaborates congenital aortic stenosis in details, Elaborates Congenital Aor...

Elaborates Congenital Aortic Stenosis in details? More common in males (4: 1). High incidence of Bicuspid Aortic valve. Murmur present from early infancy and sometimes at birth

Determine about the nervous system and behaviour, Determine about the Nervo...

Determine about the Nervous System and Behaviour Damage to certain parts of the brain will be reflected as behaviour deficits. For example, damage to the temporal lobe may affe

What are organic chemical groups that divide carbohydrates, What are the or...

What are the organic chemical groups that characterize carbohydrates? How are carbohydrates classified according to the presence of those groups? Carbohydrates are also called

Define information required for management of emergencies, Define Informati...

Define Information Required for Management of Emergencies? Management or intervention needs accurate information about the actual situation and includes many non-nutritional co

Difference in sympathetic and parasympathetic nervous system, Difference be...

Difference between Sympathetic and Parasympathetic Nervous System - S.NO . SYM P A THETIC PERASYM P A THETIC 1.

How cereal and bread important for human -nutritional factor, How Cereal an...

How Cereal and Bread important for Human -Nutritional Factor? Cereals form the staple of the Indian diet. These grains are the main source of energy in the Indian diet

Point mutations are caused by substances mutagens explain, Point mutations ...

Point mutations are often caused by substances called mutagens explain? Point mutations are often caused by substances called mutagens. Base analogs, such as 5-bromouracil, a t

Potential disadvantages - digitalis glycosides, Arrhythmias especially in p...

Arrhythmias especially in presence of hypokalemia, lack of mortality benefit. However, their efficacy in reducing the symptoms of heart failure has been established. Digoxin should

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd