Children with infective endocarditis, Biology

Assignment Help:

Among neonates, IE typically involves the tricuspid valve of structurally normal hearts and is associated with very high mortality rates.  It is likely that many of these episodes arise as a consequence of infected intra venous and right heart catheters as well as cardiac surgery. The vast majority of children with IE occurring after the neonatal period have identifiable structural cardiac abnormalities. Rheumatic heart disease is the major predisposition for IE in developing countries. Congenital heart abnormalities, particularly those involving the aortic valve; ventricular septal defects; tetralogy of Fallot; and other complex structural anomalies associated with cyanosis (TGA, single ventricle) are found in remaining cases. Of children with IE on congenital defects, 50 per cent develop infection after cardiac surgery; in these children, infection frequently involves prosthetic valves, valved conduits, or synthetic patches. Mitral valve prolapse generally in association with a regurgitant murmur has been recognized to predispose to IE in children.

Endocarditis among neonates is caused primarily by S.aureus, coagulase-negative staphylococci, and group B streptococci.  Occasionally infection is caused by  gram- negative bacilli and candida species. Among older children, streptococci, the predominant cause account for at least 40 per cent of cases, and S. aureus occurring as a nosocomial or community acquired  acute infection is the second most common cause of IE.

The clinical features and echocardiographic findings of IE in children are similar to those noted among adults with NVE or PVE, respectively. In contrast, IE among neonates is more cryptic; the clinical  picture is dominated  by  bacteremia, and classical signs of  IE  are  rare.


Related Discussions:- Children with infective endocarditis

Organic molecules, Organic Molecules Some organic molecules in life...

Organic Molecules Some organic molecules in life are Carbohydrates and Lipids à C, H and O Proteins à C, H, O, N & sometimes S Nucleic acids à C, H, O, N & P

Isolation techniques, Differentiate between spread plating and streaking?

Differentiate between spread plating and streaking?

What is the salivary digestive enzyme, What is the salivary digestive enzym...

What is the salivary digestive enzyme? Which type of food does it digest and into which smaller molecules does it transform the food? The salivary hydrolase is called as saliva

Atypical distribution of pleural fluid, Q. Atypical Distribution of Pleural...

Q. Atypical Distribution of Pleural Fluid? i) Lamellar effusion: These are shallow collections of fluid between the chest wall and the lung surface. ii) Subpulmonic

Sequencing of dna fragments, Q. If a fragment of nucleic acid has a nucleot...

Q. If a fragment of nucleic acid has a nucleotide sequence TAC can one assert that it is an anticodon or a codon? A nucleic acid having a TAC sequence surely is not tRNA it is

Why is the aids treatment often done with a drug cocktail, Q. Why is the AI...

Q. Why is the AIDS treatment often done with a drug cocktail? The treatment of obtain immune deficiency syndrome is often done with one or more anti-retroviral drugs of differe

Recurrent type, Recurrent Type In this type, euspory (seen in normal ...

Recurrent Type In this type, euspory (seen in normal cases) is replaced by aneuspory (Diplospory) because of irregular meiosis. When the spore mother ceIl functions directly

Respiratory system, whats the difference in respiratory system in mammals,r...

whats the difference in respiratory system in mammals,reptilia and amphibian?

Explain the importance of human genome project, Question 1: Explain the...

Question 1: Explain the importance of Human Genome Project in Research and list the different methods available for Gene sequencing Mention the importance of Human Genome

Explain in brief about baby blues, Regarding the article "Baby Blues" which...

Regarding the article "Baby Blues" which of the following is a false statement? A. Children, whose mothers underwent severe stressful episodes during pregnancy, have higher tha

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd