Causes of oesophagitis, Biology

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Q. Causes of oesophagitis?

The causes include tissue erosion by hydrocliloric acid (EIC1) and pepsin, with symptoms of substernal burning, cramping, pressure sensation or severe pain. These symptoms are related to:

• Anincompetent gastroesophageal sphincter,

• frequency and duration of the acid reflux, and

• Inability of the oesophagus to produce normal peristaltic waves to prevent prolonged contact of the oesophageal mucosa with the acid pepsin.


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