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Q. Causes of oesophagitis?
The causes include tissue erosion by hydrocliloric acid (EIC1) and pepsin, with symptoms of substernal burning, cramping, pressure sensation or severe pain. These symptoms are related to:
• Anincompetent gastroesophageal sphincter,
• frequency and duration of the acid reflux, and
• Inability of the oesophagus to produce normal peristaltic waves to prevent prolonged contact of the oesophageal mucosa with the acid pepsin.
Consider an axon of a neuron. At time=t1, its voltage is at threshold for an action potential; at time=t2, its voltage is at 0 millivolts prior to the peak of that action potential
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