Causes of heart failure, Biology

Assignment Help:

It is important to recognise underlying causes and precipitating factors of heart failure for its appropriate management. That would also help in prevention and treatment of heart failure. The causes could be broadly classified as those due to myocardial damage or volume overload or pressure overload or arrhythmias.

Myocardial Damage  

Coronary artery disease (myocardial ischemia or infarction), myocarditis, cardiomyopathies could lead to myocardial dysfunction.

Volume Overload Conditions

Valvular diseases (e.g. aortic regurgitation, mitral regurgitation) and congenital heart diseases (e.g. ventricular septal defect, patent ductus arteriosus)

Pressure Overload Conditions

Hypertension, aortic stenosis, coarctation of aorta impose pressure overload on the heart.

Precipitating Causes of Heart Failure

In majority of the cases one is often able to identify a precipitating cause of heart failure.

Arrhythmias

Cardiac arrhythmias are common in patients with various types of heart diseases and may precipitate or worsen heart failure through several mechanisms:

a) Tachyarrhythmias reduce ventricular filling, increase myocardial oxygen demand and in patients with coronary artery disease aggravate myocardial ischemia. This results in both systolic and diastolic dysfunction. If persistent it may cause a reversible cardiomyopathy (tachyarrhythmias induced cardiomyopathy).

b) Marked bradycardia in patients with underlying heart disease depresses cardiac output.

c) Atrioventricular dissociation results in loss of atrial boost leading to impaired ventricular filling, lower cardiac output and raised atrial pressure.

d) Abnormal intraventricular conduction impairs myocardial performance due to asynchronous ventricular contraction.


Related Discussions:- Causes of heart failure

Total arterial re-vascnlarisation, Total Arterial Re-vascnlarisation :  In...

Total Arterial Re-vascnlarisation :  In total arterial re-vascularisalion (TAR) end of the right internal mammary artery (RIMA) or radial arlery (RA) is anastomosed to the side of

Define aerobic respiration, Where in mitochondria does the process called r...

Where in mitochondria does the process called respiratory chain happen? Which are the products of the Krebs cycle used in that final phase of the aerobic respiration? Respirat

Potassium sparing diuretics, The potassium-sparing agents spironolactone, t...

The potassium-sparing agents spironolactone, triamterene, and amiloride are often useful in combination with the loop diuretics and thiazides. Triamterene and amiloride act on the

The emergency department due to the babys persistent, A mother has brought ...

A mother has brought her 2-week-old infant to the emergency department due to the baby's persistent and increasing jaundice. Blood testing reveals that the infant's unconjugated bi

Radial artery , Radial artery: Carpentier used radial aartc14y us a condui...

Radial artery: Carpentier used radial aartc14y us a conduit for CABG in 197 1. He had 30 percent early occlusion of the graft and it was given up. The mail1 problem was radi

Explain transfer of culture from one liquid media to another, Explain Trans...

Explain Transfer of Culture from One Liquid Media to another Liquid Media? 1. Inoculating loop is to be held in the right hand. It is sterilized by incineration in the inner bl

Nitrogen assimilation, The next step in the nitrogen cycle is the assimilat...

The next step in the nitrogen cycle is the assimilation of inorganic nitrogen in the type of ammonia into organic nitrogen-having compounds. Total organisms assimilate  ammonia  by

Which are plant tissues that form the plant roots, Which are plant tissues ...

Which are plant tissues that form the plant roots? Roots have a central portion called medulla made of vascular tissue outer phloem and inner xylem. Medulla is delimited by per

Describe the factors that affect cardiac, Describe the factors that affect ...

Describe the factors that affect cardiac output in a female athlete who is speed skating toward the finish line in an Olympic race.

Alive and something that is a living organism, Is there a difference betwee...

Is there a difference between something that is alive and something that is a living organism?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd