Causes of heart failure, Biology

Assignment Help:

It is important to recognise underlying causes and precipitating factors of heart failure for its appropriate management. That would also help in prevention and treatment of heart failure. The causes could be broadly classified as those due to myocardial damage or volume overload or pressure overload or arrhythmias.

Myocardial Damage  

Coronary artery disease (myocardial ischemia or infarction), myocarditis, cardiomyopathies could lead to myocardial dysfunction.

Volume Overload Conditions

Valvular diseases (e.g. aortic regurgitation, mitral regurgitation) and congenital heart diseases (e.g. ventricular septal defect, patent ductus arteriosus)

Pressure Overload Conditions

Hypertension, aortic stenosis, coarctation of aorta impose pressure overload on the heart.

Precipitating Causes of Heart Failure

In majority of the cases one is often able to identify a precipitating cause of heart failure.

Arrhythmias

Cardiac arrhythmias are common in patients with various types of heart diseases and may precipitate or worsen heart failure through several mechanisms:

a) Tachyarrhythmias reduce ventricular filling, increase myocardial oxygen demand and in patients with coronary artery disease aggravate myocardial ischemia. This results in both systolic and diastolic dysfunction. If persistent it may cause a reversible cardiomyopathy (tachyarrhythmias induced cardiomyopathy).

b) Marked bradycardia in patients with underlying heart disease depresses cardiac output.

c) Atrioventricular dissociation results in loss of atrial boost leading to impaired ventricular filling, lower cardiac output and raised atrial pressure.

d) Abnormal intraventricular conduction impairs myocardial performance due to asynchronous ventricular contraction.


Related Discussions:- Causes of heart failure

Describe the concept of the gene, Through the year of 1960s, the gene was c...

Through the year of 1960s, the gene was clearly explained as the region of DNA which gives increase to a single polypeptide or to a one RNA for genes whose final product is RNA not

Define about traumatic needles, Define about Traumatic needles Traumat...

Define about Traumatic needles Traumatic needles are needles with holes or eyes which are supplied to the hospital separate from their suture thread. The suture must be thread

Formation of vegetative and generative cells, Formation of Vegetative and G...

Formation of Vegetative and Generative Cells The division of a pollen grain results in two unequal cells-the vegetative cell and the generative cell. The pollen grain is herea

Define adverse effect - itraconazole, Adverse Effects  The most common ...

Adverse Effects  The most common adverse effects of itraconazole are dose-related nausea and abdominal discomfort. Rash and serious hepatic toxicity can happen. The drug can ca

Functions of gluconeogenesis, Functions of Gluconeogenesis The signifi...

Functions of Gluconeogenesis The significance of gluconeogenesis include: 1)  During starvation or during periods of  limited  carbohydrate intake, when  the levels of liv

Modification of carbohydrate intake for specific disorder, Define Modificat...

Define Modification of Carbohydrate Intake for Specific Disorder? In our daily diet almost 60-7096' of energy is contributed by carbohydrates. Majority of them are comprised of

Rbc & wbc, difference between RBC and WBC for homework

difference between RBC and WBC for homework

How can the binding of two amino acids, Q. How can the binding of two amino...

Q. How can the binding of two amino acids for the peptide formation be explained? A peptide is formed when a carbon from the carboxyl group of one amino acid is connected to th

Eye drops, Eye Drops Medication is instilled in the form of drops or ...

Eye Drops Medication is instilled in the form of drops or ointment.   Purpose To dilate pupil e.g. Atropine 1 per cent, drosyn 5 per cent or 10 per cent  To c

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd