Causes of heart failure, Biology

Assignment Help:

It is important to recognise underlying causes and precipitating factors of heart failure for its appropriate management. That would also help in prevention and treatment of heart failure. The causes could be broadly classified as those due to myocardial damage or volume overload or pressure overload or arrhythmias.

Myocardial Damage  

Coronary artery disease (myocardial ischemia or infarction), myocarditis, cardiomyopathies could lead to myocardial dysfunction.

Volume Overload Conditions

Valvular diseases (e.g. aortic regurgitation, mitral regurgitation) and congenital heart diseases (e.g. ventricular septal defect, patent ductus arteriosus)

Pressure Overload Conditions

Hypertension, aortic stenosis, coarctation of aorta impose pressure overload on the heart.

Precipitating Causes of Heart Failure

In majority of the cases one is often able to identify a precipitating cause of heart failure.

Arrhythmias

Cardiac arrhythmias are common in patients with various types of heart diseases and may precipitate or worsen heart failure through several mechanisms:

a) Tachyarrhythmias reduce ventricular filling, increase myocardial oxygen demand and in patients with coronary artery disease aggravate myocardial ischemia. This results in both systolic and diastolic dysfunction. If persistent it may cause a reversible cardiomyopathy (tachyarrhythmias induced cardiomyopathy).

b) Marked bradycardia in patients with underlying heart disease depresses cardiac output.

c) Atrioventricular dissociation results in loss of atrial boost leading to impaired ventricular filling, lower cardiac output and raised atrial pressure.

d) Abnormal intraventricular conduction impairs myocardial performance due to asynchronous ventricular contraction.


Related Discussions:- Causes of heart failure

Asymptomatic or mildly symptomatic patients, Q. Asymptomatic or Mildly Symp...

Q. Asymptomatic or Mildly Symptomatic Patients? The treatment is controversial. Some give them betablockers/or calcium channel blockers like verapamil, in the hope of preventin

Classification of living organisms – species, Classification of Living Orga...

Classification of Living Organisms – Species You have by now already come across the word 'species'. The word has a definite meaning in biology. Although the living world is v

Define the equilibrium potential for potassium ions, A complete motor neuro...

A complete motor neuron is removed from a frog and placed in a large volume of normal physiological saline.  The neuron is healthy; it has a stable resting voltage of -70 millivolt

How is heart contraction triggered, Q. How is heart contraction triggered? ...

Q. How is heart contraction triggered? Heart contraction is independent from neuronal stimulus although it can be modulated by the autonomous nervous system in the heart there

What is the purpose to use hydrocolloids, Hydrocolloids are extremely versa...

Hydrocolloids are extremely versatile and are used for many other purposes including: (a) Production of pseudoplasticity  (i.e. fluidity under shear) at high temperatures to ea

Symptoms and signs of diabetes mellitus, Symptoms refer to the problems exp...

Symptoms refer to the problems expressed by the patients. Signs are obtained by a health professional from the patients by interacting with him, by conducting tests, etc. The sympt

What is the prevention of perinatal transmission, Prevention of perinatal t...

Prevention of perinatal transmission  Zidovudine alone, started at 14-34 weeks of gestation and continued in the infant for the first 6 weeks of life, reduced HIV transmission

Are there chloroplasts in cyanobacteria, Are there chloroplasts in cyanobac...

Are there chloroplasts in cyanobacteria? In cyanobacteria there are no chloroplasts and the chlorophyll layers are dispersed in cytosol. Which chemical element is central in

Explain the catabolic responses, Explain the Catabolic Responses? Hormo...

Explain the Catabolic Responses? Hormonal responses during the hyper inetabolic phase of infection are same as in case of injury. Serum cortisol levels are elevated, glycogen i

Working glucagon and insulin for the blood glucose control, Q. What are the...

Q. What are the functions of glucagon and insulin for the blood glucose control? Glucagon increases insulin and glycemia reduces it. They are antagonistic pancreatic hormones.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd