Causes of heart failure, Biology

Assignment Help:

It is important to recognise underlying causes and precipitating factors of heart failure for its appropriate management. That would also help in prevention and treatment of heart failure. The causes could be broadly classified as those due to myocardial damage or volume overload or pressure overload or arrhythmias.

Myocardial Damage  

Coronary artery disease (myocardial ischemia or infarction), myocarditis, cardiomyopathies could lead to myocardial dysfunction.

Volume Overload Conditions

Valvular diseases (e.g. aortic regurgitation, mitral regurgitation) and congenital heart diseases (e.g. ventricular septal defect, patent ductus arteriosus)

Pressure Overload Conditions

Hypertension, aortic stenosis, coarctation of aorta impose pressure overload on the heart.

Precipitating Causes of Heart Failure

In majority of the cases one is often able to identify a precipitating cause of heart failure.

Arrhythmias

Cardiac arrhythmias are common in patients with various types of heart diseases and may precipitate or worsen heart failure through several mechanisms:

a) Tachyarrhythmias reduce ventricular filling, increase myocardial oxygen demand and in patients with coronary artery disease aggravate myocardial ischemia. This results in both systolic and diastolic dysfunction. If persistent it may cause a reversible cardiomyopathy (tachyarrhythmias induced cardiomyopathy).

b) Marked bradycardia in patients with underlying heart disease depresses cardiac output.

c) Atrioventricular dissociation results in loss of atrial boost leading to impaired ventricular filling, lower cardiac output and raised atrial pressure.

d) Abnormal intraventricular conduction impairs myocardial performance due to asynchronous ventricular contraction.


Related Discussions:- Causes of heart failure

Biomolecules, How do you explain in the absence of aldehyde group in the pe...

How do you explain in the absence of aldehyde group in the pentaacetate of D-glucose? Ans) when you react glucose with acetic anhydrate it forms pentaacetate with 5 OH grops it tel

Measurement of solar energy input-radiation instruments, Measurement of sol...

Measurement of solar energy input A variety of instruments have been designed to measure the energy of solar radiations of all wavelengths as well as of a particular range of w

Iodine - mineral elements, IODINE The element is available is drinking ...

IODINE The element is available is drinking water, vegetables and fish. Table salts are also compulsorily iodized to provide iodine in the diet. All sea foods are rich in

Proteins, assignment on the topic proteins

assignment on the topic proteins

Acupunture-osteopathy-herbal therapy, Alternative Therapies Assignment 1...

Alternative Therapies Assignment 1. A. Acupunture, B.  Osteopathy, C.  Herbal therapy For each one of alternative therapies above, answers the three questions below! 1. Th

What is clinical deficiency presented by hemophilic people, What is the cli...

What is the clinical deficiency presented by hemophilic people? What is the genetic cause of that deficiency? The Hemophilia is a disease characterized by impaired blood clotti

Define systematic botany - taxonomy, Define Systematic Botany - Taxonomy? ...

Define Systematic Botany - Taxonomy? We will now learn something mare about systematic botany. The early recognition of harmful and useful plants was the beginning of systemati

Phosphodiesterase inhibitors, Phosphodiesterase Inhibitors and Other Agents...

Phosphodiesterase Inhibitors and Other Agents Amrinone and Milrinone are prototypes of type III PDE inhibitors. They decrease the breakdown of cyclic AMP in the myocardium and i

Explain briefly about vitamin B12, Vitamin B 12 (Cyanocobalamin) Vitam...

Vitamin B 12 (Cyanocobalamin) Vitamin B 12 refers to a group of Cobalt-containing corrinoids known as cobalamins. It is also called antipernicious- anemia factor, extrinsic f

Define about the paracellular route - calcium, Define about the Paracellula...

Define about the Paracellular Route - Calcium? It involves passive Ca transport through the tight junctions between mucosal cells. The salient features include: It is in

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd