Causes of heart failure, Biology

Assignment Help:

It is important to recognise underlying causes and precipitating factors of heart failure for its appropriate management. That would also help in prevention and treatment of heart failure. The causes could be broadly classified as those due to myocardial damage or volume overload or pressure overload or arrhythmias.

Myocardial Damage  

Coronary artery disease (myocardial ischemia or infarction), myocarditis, cardiomyopathies could lead to myocardial dysfunction.

Volume Overload Conditions

Valvular diseases (e.g. aortic regurgitation, mitral regurgitation) and congenital heart diseases (e.g. ventricular septal defect, patent ductus arteriosus)

Pressure Overload Conditions

Hypertension, aortic stenosis, coarctation of aorta impose pressure overload on the heart.

Precipitating Causes of Heart Failure

In majority of the cases one is often able to identify a precipitating cause of heart failure.

Arrhythmias

Cardiac arrhythmias are common in patients with various types of heart diseases and may precipitate or worsen heart failure through several mechanisms:

a) Tachyarrhythmias reduce ventricular filling, increase myocardial oxygen demand and in patients with coronary artery disease aggravate myocardial ischemia. This results in both systolic and diastolic dysfunction. If persistent it may cause a reversible cardiomyopathy (tachyarrhythmias induced cardiomyopathy).

b) Marked bradycardia in patients with underlying heart disease depresses cardiac output.

c) Atrioventricular dissociation results in loss of atrial boost leading to impaired ventricular filling, lower cardiac output and raised atrial pressure.

d) Abnormal intraventricular conduction impairs myocardial performance due to asynchronous ventricular contraction.


Related Discussions:- Causes of heart failure

Why deficiency of folate take place, Why Deficiency of Folate take place? ...

Why Deficiency of Folate take place? If there is inadequate dietary folate, the activity of both the DNA and the methylation cycles, described above, will be reduced. A decrea

Two major causes of severe protein energy malnutrition, Explain Two major c...

Explain Two major causes of severe Protein Energy Malnutrition? Two major causes of severe PEM are diluted milk formulae and infections, especially diarrhoea in poor communiti

Show imbalances of basal nuclei, Q. Show Imbalances of basal nuclei? BA...

Q. Show Imbalances of basal nuclei? BASAL NUCLEI - Gray matter "islands" located deep within cerebral white matter. These nuclei process a variety of descending motor informat

Explain the term blood, Explain the term Blood Blood is a fluid and con...

Explain the term Blood Blood is a fluid and consists of plasma and blood cells. More than 90 percent of plasma is water. Other constituents of plasma are plasma proteins i.e. a

Syngamy - protozoan, Syngamy - Protozoan The two gametes may be morpho...

Syngamy - Protozoan The two gametes may be morphologically similar (isogametes) or dissimilar (anisogametes). The gametes also vary in form, they may be flagellated or amoeboi

Reproduction, write about asexual reproduction in mucor

write about asexual reproduction in mucor

How does parafunctional habits lead to implant failure, How does parafuncti...

How does parafunctional habits lead to implant failure Parafunctional habits like bruxism and clenching create mechanical and biological problems due to overloading and is cons

State about bone physiology, State about Bone physiology Bone physiolog...

State about Bone physiology Bone physiology that is most relevant to the study of mechanically mediated bone adaptation and its relevance in implant dentistry. These aspects in

What are the symptoms of dyslipidemia, Q. What are the Symptoms of dyslipid...

Q. What are the Symptoms of dyslipidemia? The main symptom is presence of xanthoma: This is a yellowish swelling, nodule or plaque in the skin resulting from deposits of fat. T

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd