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This innovative, pacemaker-based approach to the treatment of patients with heart failure who have a wide QRS complex (>140 ms) on 12-lead ECG aims at providing electromechanical coordination and improved ventricular synchrony in symptomatic patients who have severe systolic dysfunction and clinically significant intraventricular conduction defects, particularly left bundle-branch block. A percutaneous, three-lead, biventricular pacemaker system is used; one lead is placed in the right atrium, one is placed in the right ventricle, and a third is passed through the right atrium, through the coronary sinus, and into a cardiac vein on the lateral wall of the left ventricle.
Beneficial effects include reverse remodeling, resulting in decreased heart size and ventricular volumes, improved ejection fraction, and decreased mitral regurgitation. Clinical improvements in exercise tolerance, quality of life, and the rate of hospitalization have been documented. However resynchronization therapy has not been shown to enhance survival.
The long term adaptive mechanisms involve myocardial hypertrophy and remodeling which occurs slowly over weeks to months. The capacity of these adaptive mechanisms meant to sust
The bar-tailed godwit, Limosa lapponica baueri, or kuaka, is a wading shorebird seen on marshy estuaries and wetlands during the New Zealand summer. Populations of this species emb
Biologists established that new cells Consequent to this doctrine, biologists established that new cells are formed by cell division and by the end of the nineteenth century, t
How is claimant need to make balance of probability? When there is no loss suffered through a person after that there cannot be a civil proceeding not like under criminal law t
Catecholamines increase activation of Ca 2+ via beta-adrenergic receptors and the adenyl cyclase system. Dopamine has both alpha and beta and dopaminergic effects. Its beta ef
Homologous Recombination is the exchange of the sequence between two associated but different DNA (or RNA) molecules, with the result that a new "chimeric" molecule is obtained. S
Adenosine triphosphate (ATP) is a general form in which the energy is stored in living systems; comprises of a nucleotide (with ribose sugar) with three phosphate groups. Energy c
What are risk factors for diseases? Risk factors for a disease are everything that contributes to enhance the risk of the disease to appear. For instance, for most cardiovascul
Excretory organ of crustaceans and agama lizard
Immunogenicity The safety and immunogenicity of the new vaccine was evaluated in two unpublished studies that are summarized in the package insert. Among 1280 adults (18-55 ye
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