Cardiac resynchronization therapy, Biology

Assignment Help:

This innovative, pacemaker-based approach to the treatment of patients with heart failure who have a wide QRS complex (>140 ms) on 12-lead ECG aims at providing electromechanical coordination and improved ventricular synchrony in symptomatic patients who have severe systolic dysfunction and clinically significant intraventricular conduction defects, particularly left bundle-branch block. A percutaneous, three-lead, biventricular pacemaker system is used; one lead is placed in the right atrium, one is placed in the right ventricle, and a third is passed through the right atrium, through the coronary sinus, and into a cardiac vein on the lateral wall of the left ventricle. 

Beneficial effects include reverse remodeling, resulting in decreased heart size and ventricular volumes, improved ejection fraction, and decreased mitral regurgitation. Clinical improvements in exercise tolerance, quality of life, and the rate of hospitalization have been documented. However resynchronization therapy has not been shown to enhance survival.


Related Discussions:- Cardiac resynchronization therapy

State in brief about the macronutrients, State  in brief about the Macronut...

State  in brief about the Macronutrients  Each element is specific in its function in plant metabolism, however, the exact functions for a number of them are still not known. T

Threshold for an action potential in neuron a, Neuron A is a healthy neuron...

Neuron A is a healthy neuron with all the usual ion channels.  When at rest with a membrane voltage of R millivolts, neuron A produces no action potentials.  The voltage thresh

Indication of exchange transfusion, Indication of Exchange Transfusion ...

Indication of Exchange Transfusion i) Early exchange transfusion is indicated in the presence of hydrops and is often indicated by a history of previously severely aff

Complications in dyslipidemia, Q. Complications in dyslipidemia? The co...

Q. Complications in dyslipidemia? The complications include: • Pancreatitis • Progressive atherosclerosis or asymptomatic coronary. Excess of triglycerides (hypertrigl

Explain endonucleases, Explain Endonucleases Endonucleases  are  nucle...

Explain Endonucleases Endonucleases  are  nucleases present  in  the pancreatic juice like RNAase  andDNAase. These hydrolyze internal phosphodiester bonds which are located m

Explain the frenal and muscle attachments, Frenal and Muscle Attachments: ...

Frenal and Muscle Attachments: Frenal attachment at the site of implant placement has to be evaluated. A high frenal attachment may have a definite pull on the gingival surroun

Comparison to healthy lungs, The nature of the sounds produced by percussio...

The nature of the sounds produced by percussion (tapping) a patient's chest can tell a physician a great deal about the condition of the organs within the thoracic cavity. Healthy,

Explain about carrier proteins transport substances, How do carrier protein...

How do carrier proteins transport substances across cell membranes? Carrier proteins bind to a molecule of the substance on single side of the membrane, change shape, transpor

Explain the term - migraine, Explain the term - Migraine Perhaps the mo...

Explain the term - Migraine Perhaps the most common neurological disorder, migraine afflicts some 5% to 20% of the population at some time in their lives. The World Federation

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd