Camptotheca acuminata, Biology

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This species is an ornamental tree in China, and has yielded the clinically active agents topotecan, irinotecan, and 9 -aminocamptothecin, which are semisynthetically derived from camptothecin. Camptothecin is now marketed under the generic name ‘Topotecan' and the brand name ‘Navelbine' by SKB.


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